Search Results - "Park, Jae Il"

Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex by Jung, Youn-Sang, Park, Jae-Il

“…Wnt/β-catenin signaling is implicated in many physiological processes, including development, tissue homeostasis, and tissue regeneration. In human cancers,…”
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TMEM9‐v‐ATPase Activates Wnt/β‐Catenin Signaling Via APC Lysosomal Degradation for Liver Regeneration and Tumorigenesis by Jung, Youn‐Sang, Stratton, Sabrina A., Lee, Sung Ho, Kim, Moon‐Jong, Jun, Sohee, Zhang, Jie, Zheng, Biyun, Cervantes, Christopher L., Cha, Jong‐Ho, Barton, Michelle C., Park, Jae‐Il

“…Background and Aims How Wnt signaling is orchestrated in liver regeneration and tumorigenesis remains elusive. Recently, we identified transmembrane protein 9…”
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Wnt signaling in liver regeneration, disease, and cancer by Zou, Gengyi, Park, Jae-Il

“…The liver exhibits the highest recovery rate from acute injuries. However, in chronic liver disease, the long-term loss of hepatocytes often leads to adverse…”
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Robust PEDOT:PSS Wet‐Spun Fibers for Thermoelectric Textiles by Kim, Youngseok, Lund, Anja, Noh, Hyebin, Hofmann, Anna I., Craighero, Mariavittoria, Darabi, Sozan, Zokaei, Sepideh, Park, Jae Il, Yoon, Myung‐Han, Müller, Christian

“…To realize thermoelectric textiles that can convert body heat to electricity, fibers with excellent mechanical and thermoelectric properties are needed…”
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PTPN14 is required for the density-dependent control of YAP1 by Wang, Wenqi, Huang, Jun, Wang, Xin, Yuan, Jingsong, Li, Xu, Feng, Lin, Park, Jae-Il, Chen, Junjie

“…Through an shRNA-mediated loss-of-function screen, we identified PTPN14 as a potential tumor suppressor. PTPN14 interacts with yes-associated protein 1 (YAP1),…”
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GPx3-mediated redox signaling arrests the cell cycle and acts as a tumor suppressor in lung cancer cell lines by An, Byung Chull, Choi, Yoo-Duk, Oh, In-Jae, Kim, Ju Han, Park, Jae-Il, Lee, Seung-Won

“…Glutathione peroxidase 3 (GPx3), a major scavenger of reactive oxygen species (ROS) in plasma, acts as a redox signal modulator. However, the mechanism…”
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LIG4 mediates Wnt signalling-induced radioresistance by Jun, Sohee, Jung, Youn-Sang, Suh, Han Na, Wang, Wenqi, Kim, Moon Jong, Oh, Young Sun, Lien, Esther M., Shen, Xi, Matsumoto, Yoshihisa, McCrea, Pierre D., Li, Lei, Chen, Junjie, Park, Jae-Il

“…Despite the implication of Wnt signalling in radioresistance, the underlying mechanisms are unknown. Here we find that high Wnt signalling is associated with…”
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A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia by Shen, Xi, Wang, Rui, Kim, Moon Jong, Hu, Qianghua, Hsu, Chih-Chao, Yao, Jun, Klages-Mundt, Naeh, Tian, Yanyan, Lynn, Erica, Brewer, Thomas F., Zhang, Yilei, Arun, Banu, Gan, Boyi, Andreeff, Michael, Takeda, Shunichi, Chen, Junjie, Park, Jae-il, Shi, Xiaobing, Chang, Christopher J., Jung, Sung Yun, Qin, Jun, Li, Lei

“…Impaired DNA crosslink repair leads to Fanconi anemia (FA), characterized by a unique manifestation of bone marrow failure and pancytopenia among diseases…”
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Bone Remodeling: Histone Modifications as Fate Determinants of Bone Cell Differentiation by Yi, Sun-Ju, Lee, Hyerim, Lee, Jisu, Lee, Kyubin, Kim, Junil, Kim, Yeojin, Park, Jae-Il, Kim, Kyunghwan

“…The bone tissue is a dynamic complex that constitutes of several interdependent systems and is continuously remodeled through the concerted actions of bone…”
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PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness by Wang, Xin, Jung, Youn-Sang, Jun, Sohee, Lee, Sunhye, Wang, Wenqi, Schneider, Andrea, Sun Oh, Young, Lin, Steven H., Park, Bum-Joon, Chen, Junjie, Keyomarsi, Khandan, Park, Jae-Il

“…Cancer stem cells (CSCs) contribute to tumour heterogeneity, therapy resistance and metastasis. However, the regulatory mechanisms of cancer cell stemness…”
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Dyrk2-associated EDD-DDB1-VprBP E3 Ligase Inhibits Telomerase by TERT Degradation by Jung, Hae-Yun, Wang, Xin, Jun, Sohee, Park, Jae-Il

“…Telomerase maintains the telomere, a specialized chromosomal end structure that is essential for genomic stability and cell immortalization. Telomerase is not…”
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Quiescence Exit of Tert+ Stem Cells by Wnt/β-Catenin Is Indispensable for Intestinal Regeneration by Suh, Han Na, Kim, Moon Jong, Jung, Youn-Sang, Lien, Esther M., Jun, Sohee, Park, Jae-Il

“…Fine control of stem cell maintenance and activation is crucial for tissue homeostasis and regeneration. However, the mechanism of quiescence exit of Tert+…”
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Tetracycline Analogs Inhibit Osteoclast Differentiation by Suppressing MMP-9-Mediated Histone H3 Cleavage by Kim, Yeojin, Kim, Jinman, Lee, Hyerim, Shin, Woo-Ri, Lee, Sheunghun, Lee, Jisu, Park, Jae-Il, Jhun, Byung Hak, Kim, Yang-Hoon, Yi, Sun-Ju, Kim, Kyunghwan

“…Osteoporosis is a common disorder of bone remodeling, caused by the imbalance between bone resorption by osteoclasts and bone formation by osteoblasts…”
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Effect of Ishophloroglucin A Isolated from Ishige okamurae on In Vitro Osteoclastogenesis and Osteoblastogenesis by Cho, Su-Hyeon, Kim, Hyun-Soo, Jung, Hye-Yeon, Park, Jae-Il, Jang, You-Jee, Ahn, Juhee, Kim, Kil-Nam

“…The balance between bone-resorbing osteoclasts and bone-forming osteoblasts is essential for the bone remodeling process. This study aimed to investigate the…”
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CRACD loss induces neuroendocrine cell plasticity of lung adenocarcinoma by Kim, Bongjun, Zhang, Shengzhe, Huang, Yuanjian, Ko, Kyung-Pil, Jung, Youn-Sang, Jang, Jinho, Zou, Gengyi, Zhang, Jie, Jun, Sohee, Kim, Kee-Beom, Park, Kwon-Sik, Park, Jae-Il

“…Tumor cell plasticity contributes to intratumoral heterogeneity and therapy resistance. Through cell plasticity, some lung adenocarcinoma (LUAD) cells…”
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TMBIM6 deficiency leads to bone loss by accelerating osteoclastogenesis by Yi, Sun-Ju, Jang, You-Jee, Lee, Seokchan, Cho, Sung-Jin, Kang, Kyuho, Park, Jae-Il, Chae, Han-Jung, Kim, Hyung-Ryong, Kim, Kyunghwan

“…TMBIM6 is an endoplasmic reticulum (ER) protein that modulates various physiological and pathological processes, including metabolism and cancer. However, its…”
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Effects of Alginate Oligosaccharide on Testosterone-Induced Benign Prostatic Hyperplasia in Orchiectomized Rats by Jang, You-Jee, Jung, Hye-Yeon, Myeong, Ju-Yeong, Song, Kwang Hoon, Kwon, Joseph, Kim, Duwoon, Park, Jae-Il

“…Benign prostatic hyperplasia (BPH) is an age-related disease of the urinary system that affects elderly men. Current treatments for BPH are associated with…”
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Dynamic mucus secretion in ventral surfaces of toe pads of the tree frog (Dryophytes japonica) by SEOL, Jae‐Uk, PARK, Jung Su, LIM, Jae‐Hong, HWANG, Hyeon Su, KIM, Eun‐Bin, KIM, Seob‐Gu, PARK, Jae‐Il, SUNG, Ha‐Cheol, KIM, Joon Heon, KIM, Eung‐Sam

“…The tree frog is a prominent amphibian among terrestrial vertebrates known for its ability to adhere to various surfaces through the capillary forces of water…”
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High-glucose-induced CARM1 expression regulates apoptosis of human retinal pigment epithelial cells via histone 3 arginine 17 dimethylation: Role in diabetic retinopathy by Kim, Dong-il, Park, Min-jung, Lim, Seul-ki, Choi, Joo-hee, Kim, Jong-choon, Han, Ho-jae, Kundu, Tapas K., Park, Jae-il, Yoon, Kyung-chul, Park, Sang-woo, Park, Jong-sung, Heo, Young-ran, Park, Soo-hyun

“…•The pathophysiological role of CARM1 in high-glucose-induced RPE cell apoptosis.•The epigenetic modification of histone 3 arginine 17 in RPE cell…”
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Hybrid manufacturing in micro/nano scale: A Review by Chu, Won-Shik, Kim, Chung-Soo, Lee, Hyun-Taek, Choi, Jung-Oh, Park, Jae-Il, Song, Ji-Hyeon, Jang, Ki-Hwan, Ahn, Sung-Hoon

“…In this paper, a total of 57 micro and nano scale hybrid manufacturing processes are reviewed. These processes are categorized in terms of process timing and…”
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