Search Results - "Park, Il Ho"

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  1. 1

    Glucocorticoids ameliorate TGF-β1-mediated epithelial-to-mesenchymal transition of airway epithelium through MAPK and Snail/Slug signaling pathways by Yang, Hyun-Woo, Lee, Seoung-Ae, Shin, Jae-Min, Park, Il-Ho, Lee, Heung-Man

    Published in Scientific reports (14-06-2017)
    “…Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue…”
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    Journal Article
  2. 2

    Inhibitory effect of doxycycline conjugated with deoxycholic acid and polyethylenimine conjugate on nasal fibroblast differentiation and extracellular production by Shin, Jae-Min, Yang, Hyun-Woo, Lim, Su-Yeon, Jeong, Ji-Hoon, Park, Il-Ho

    Published in PloS one (16-05-2024)
    “…Chronic rhinosinusitis (CRS) is an inflammatory disease affecting the sinuses or nose. Persistent inflammatory responses can lead to tissue remodeling, which…”
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  3. 3

    Eosinophilic Chronic Rhinosinusitis and Pathogenic Role of Protease by Kim, Jaehyeong, Kwak, Sooun, Lee, Juhyun, Park, Il-Ho, Lee, Seung Hoon, Shin, Jae Min, Kim, Tae Hoon

    “…Chronic rhinosinusitis (CRS) is an inflammation of the nasal and paranasal sinus mucosa, and eosinophilic CRS (eCRS) is a subtype characterized by significant…”
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  4. 4

    Diesel Exhaust Particles Upregulate Interleukins IL-6 and IL-8 in Nasal Fibroblasts by Kim, Jin Ah, Cho, Jae Hoon, Park, Il-Ho, Shin, Jae-Min, Lee, Seoung-Ae, Lee, Heung-Man

    Published in PloS one (13-06-2016)
    “…Diesel exhaust particles (DEP) are a major source of air pollution. Nasal fibroblasts are known to produce various cytokines and chemokines. The aim of this…”
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  5. 5

    Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium by Park, Il-Ho, Kang, Ju-Hyung, Shin, Jae-Min, Lee, Heung-Man

    Published in PloS one (01-08-2016)
    “…Tissue remodeling is believed to cause recalcitrant chronic rhinosinusitis (CRS). Epithelial-mesenchymal transition (EMT) is a novel clinical therapeutic…”
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  6. 6

    Lipopolysaccharide induces pro-inflammatory cytokines and MMP production via TLR4 in nasal polyp-derived fibroblast and organ culture by Cho, Jung-Sun, Kang, Ju-Hyung, Um, Ji-Young, Han, In-Hye, Park, Il-Ho, Lee, Heung-Man

    Published in PloS one (12-11-2014)
    “…Nasal polyposis is characterized by persistent inflammation and remodeling in sinonasal mucosa. Toll-like receptors (TLRs) play a role in the innate immune…”
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  7. 7

    DNMTs Are Involved in TGF-β1-Induced Epithelial-Mesenchymal Transitions in Airway Epithelial Cells by Park, Joo-Hoo, Shin, Jae-Min, Yang, Hyun-Woo, Park, Il-Ho

    “…Chronic rhinosinusitis (CRS) pathogenesis is closely related to tissue remodeling, including epithelial-mesenchymal transition (EMT). Epigenetic mechanisms…”
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  8. 8

    Comparison of the human microbiome in adults and children with chronic rhinosinusitis by Park, Il-Ho, Lee, Joong Seob, Park, Joo-Hoo, Kang, Sung Hun, Hong, Seok Min, Park, Il Seok, Yoon, Joo Heung, Hong, Seok Jin

    Published in PloS one (02-12-2020)
    “…We hypothesized that differences in the microbiome could be a cause of the substantial differences in the symptoms of and treatment options for adult and…”
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  9. 9

    Changing Trends in the Clinical Characteristics and Treatment Strategies for Odontogenic Sinusitis Over the Past 10 Years by Shin, Jae-Min, Kim, Su-Jong, Lee, Heung-Man, Park, Il-Ho

    Published in Ear, nose, & throat journal (01-11-2024)
    “…Objectives The incidence of odontogenic sinusitis has been gradually increasing due to the recent increases in invasive dental procedures. This study aimed to…”
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  10. 10

    Different Methods and Formulations of Drugs and Vaccines for Nasal Administration by Tai, Junhu, Han, Munsoo, Lee, Dabin, Park, Il-Ho, Lee, Sang Hag, Kim, Tae Hoon

    Published in Pharmaceutics (17-05-2022)
    “…Nasal drug delivery is advantageous when compared with other routes of drug delivery as it avoids the hepatic first-pass effect, blood-brain barrier…”
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  11. 11

    Proteomic analysis of pure human airway gland mucus reveals a large component of protective proteins by Joo, Nam Soo, Evans, Idil Apak T, Cho, Hyung-Ju, Park, Il-Ho, Engelhardt, John F, Wine, Jeffrey J

    Published in PloS one (23-02-2015)
    “…Airway submucosal glands contribute to innate immunity and protect the lungs by secreting mucus, which is required for mucociliary clearance and which also…”
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  12. 12

    Glycolytic reprogramming is involved in tissue remodeling on chronic rhinosinusitis by Jo, Min-Sik, Yang, Hyun-Woo, Park, Joo-Hoo, Shin, Jae-Min, Park, Il-Ho

    Published in PloS one (16-02-2023)
    “…Glycolytic reprogramming is a key feature of chronic inflammatory disease. Extracellular matrix (ECM) produced by myofibroblasts plays an important role in…”
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  13. 13

    miR-29b Regulates TGF-β1-Induced Epithelial-Mesenchymal Transition by Inhibiting Heat Shock Protein 47 Expression in Airway Epithelial Cells by Shin, Jae-Min, Park, Joo-Hoo, Yang, Hyun-Woo, Moon, Jee Won, Lee, Heung-Man, Park, Il-Ho

    “…Tissue remodeling contributes to ongoing inflammation and refractoriness of chronic rhinosinusitis (CRS). During this process, epithelial-mesenchymal…”
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  14. 14

    Stimulator of Interferon Gene Agonists Induce an Innate Antiviral Response against Influenza Viruses by Lee, Hyun Jung, Park, Joo-Hoo, Park, Il-Ho, Shin, Ok Sarah

    Published in Viruses (27-05-2024)
    “…The devastating effects of COVID-19 have highlighted the importance of prophylactic and therapeutic strategies to combat respiratory diseases. Stimulator of…”
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  15. 15

    Ultrasound cavitation: a reliable non-enzymatic method for adipose-derived mesenchymal stem cell (ADSC) isolation by Park, Joo-Hoo, Choi, Yujin, Shin, Jae-Min, Yang, Hyun-Woo, Jeong, Seong-Ho, Park, Il-Ho

    Published in Stem cell research & therapy (06-06-2023)
    “…Adipose tissue is known to serve as an abundant and readily accessible source of adipose-derived stem cells (ADSCs) as an alternative to bone marrow…”
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  16. 16

    Eosinophil-Derived Osteopontin Induces the Expression of Pro-Inflammatory Mediators and Stimulates Extracellular Matrix Production in Nasal Fibroblasts: The Role of Osteopontin in Eosinophilic Chronic Rhinosinusitis by Yang, Hyun-Woo, Park, Joo-Hoo, Jo, Min-Sik, Shin, Jae-Min, Kim, Dae Woo, Park, Il-Ho

    Published in Frontiers in immunology (02-03-2022)
    “…Eosinophilic chronic rhinosinusitis (ECRS) is a subtype of chronic rhinosinusitis (CRS) and is a refractory or intractable disease. However, a reliable…”
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  17. 17

    Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation by Moon, Jee Won, Choi, Seok-Youl, Kim, Su-Jong, Shin, Jae-Min, Park, Il-Ho

    “…Background Biocompatibility and stability of three-dimensional printed polycaprolactone mesh grafts for nasal surgery are proven in both animal and human…”
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  18. 18

    Decreased expression of CCL17 in the disrupted nasal polyp epithelium and its regulation by IL-4 and IL-5 by Kim, Byoungjae, Lee, Hyun-Ji, Im, Nu-Ri, Lee, Doh Young, Kim, Ha Kyun, Kang, Cha Young, Park, Il-Ho, Lee, Seung Hoon, Lee, Heung-Man, Lee, Sang Hag, Baek, Seung-Kuk, Kim, Tae Hoon

    Published in PloS one (10-05-2018)
    “…In airway epithelium, thymus and activation-regulated chemokine (CCL17) and macrophage-derived chemokine (CCL22) are induced by defective epithelial barriers…”
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  19. 19

    Vitamin D attenuates myofibroblast differentiation and extracellular matrix accumulation in nasal polyp-derived fibroblasts through smad2/3 signaling pathway by Lee, Seoung-Ae, Yang, Hyun-Woo, Um, Ji-Young, Shin, Jae-Min, Park, Il-Ho, Lee, Heung-Man

    Published in Scientific reports (04-08-2017)
    “…To investigate the potential role of vitamin D (1,25(OH) 2 D 3 ) in preventing the development of nasal polyps, we examined the effect of vitamin D on…”
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  20. 20

    Baicalin Down-Regulates IL-1β-Stimulated Extracellular Matrix Production in Nasal Fibroblasts by Shin, Jae-Min, Kang, Ju-Hyung, Lee, Seoung-Ae, Park, Il-Ho, Lee, Heung-Man

    Published in PloS one (21-12-2016)
    “…Baicalin, a Chinese herbal medicine, has anti-fibrotic and anti-inflammatory effects. The aims of present study were to investigate the effects of baicalin on…”
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