Search Results - "Park, Il Ho"
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Glucocorticoids ameliorate TGF-β1-mediated epithelial-to-mesenchymal transition of airway epithelium through MAPK and Snail/Slug signaling pathways
Published in Scientific reports (14-06-2017)“…Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue…”
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2
Inhibitory effect of doxycycline conjugated with deoxycholic acid and polyethylenimine conjugate on nasal fibroblast differentiation and extracellular production
Published in PloS one (16-05-2024)“…Chronic rhinosinusitis (CRS) is an inflammatory disease affecting the sinuses or nose. Persistent inflammatory responses can lead to tissue remodeling, which…”
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3
Eosinophilic Chronic Rhinosinusitis and Pathogenic Role of Protease
Published in International journal of molecular sciences (12-12-2023)“…Chronic rhinosinusitis (CRS) is an inflammation of the nasal and paranasal sinus mucosa, and eosinophilic CRS (eCRS) is a subtype characterized by significant…”
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4
Diesel Exhaust Particles Upregulate Interleukins IL-6 and IL-8 in Nasal Fibroblasts
Published in PloS one (13-06-2016)“…Diesel exhaust particles (DEP) are a major source of air pollution. Nasal fibroblasts are known to produce various cytokines and chemokines. The aim of this…”
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5
Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium
Published in PloS one (01-08-2016)“…Tissue remodeling is believed to cause recalcitrant chronic rhinosinusitis (CRS). Epithelial-mesenchymal transition (EMT) is a novel clinical therapeutic…”
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6
Lipopolysaccharide induces pro-inflammatory cytokines and MMP production via TLR4 in nasal polyp-derived fibroblast and organ culture
Published in PloS one (12-11-2014)“…Nasal polyposis is characterized by persistent inflammation and remodeling in sinonasal mucosa. Toll-like receptors (TLRs) play a role in the innate immune…”
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DNMTs Are Involved in TGF-β1-Induced Epithelial-Mesenchymal Transitions in Airway Epithelial Cells
Published in International journal of molecular sciences (10-03-2022)“…Chronic rhinosinusitis (CRS) pathogenesis is closely related to tissue remodeling, including epithelial-mesenchymal transition (EMT). Epigenetic mechanisms…”
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Comparison of the human microbiome in adults and children with chronic rhinosinusitis
Published in PloS one (02-12-2020)“…We hypothesized that differences in the microbiome could be a cause of the substantial differences in the symptoms of and treatment options for adult and…”
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Changing Trends in the Clinical Characteristics and Treatment Strategies for Odontogenic Sinusitis Over the Past 10 Years
Published in Ear, nose, & throat journal (01-11-2024)“…Objectives The incidence of odontogenic sinusitis has been gradually increasing due to the recent increases in invasive dental procedures. This study aimed to…”
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10
Different Methods and Formulations of Drugs and Vaccines for Nasal Administration
Published in Pharmaceutics (17-05-2022)“…Nasal drug delivery is advantageous when compared with other routes of drug delivery as it avoids the hepatic first-pass effect, blood-brain barrier…”
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11
Proteomic analysis of pure human airway gland mucus reveals a large component of protective proteins
Published in PloS one (23-02-2015)“…Airway submucosal glands contribute to innate immunity and protect the lungs by secreting mucus, which is required for mucociliary clearance and which also…”
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12
Glycolytic reprogramming is involved in tissue remodeling on chronic rhinosinusitis
Published in PloS one (16-02-2023)“…Glycolytic reprogramming is a key feature of chronic inflammatory disease. Extracellular matrix (ECM) produced by myofibroblasts plays an important role in…”
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13
miR-29b Regulates TGF-β1-Induced Epithelial-Mesenchymal Transition by Inhibiting Heat Shock Protein 47 Expression in Airway Epithelial Cells
Published in International journal of molecular sciences (26-10-2021)“…Tissue remodeling contributes to ongoing inflammation and refractoriness of chronic rhinosinusitis (CRS). During this process, epithelial-mesenchymal…”
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14
Stimulator of Interferon Gene Agonists Induce an Innate Antiviral Response against Influenza Viruses
Published in Viruses (27-05-2024)“…The devastating effects of COVID-19 have highlighted the importance of prophylactic and therapeutic strategies to combat respiratory diseases. Stimulator of…”
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15
Ultrasound cavitation: a reliable non-enzymatic method for adipose-derived mesenchymal stem cell (ADSC) isolation
Published in Stem cell research & therapy (06-06-2023)“…Adipose tissue is known to serve as an abundant and readily accessible source of adipose-derived stem cells (ADSCs) as an alternative to bone marrow…”
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Eosinophil-Derived Osteopontin Induces the Expression of Pro-Inflammatory Mediators and Stimulates Extracellular Matrix Production in Nasal Fibroblasts: The Role of Osteopontin in Eosinophilic Chronic Rhinosinusitis
Published in Frontiers in immunology (02-03-2022)“…Eosinophilic chronic rhinosinusitis (ECRS) is a subtype of chronic rhinosinusitis (CRS) and is a refractory or intractable disease. However, a reliable…”
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17
Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation
Published in Journal of otolaryngology-head and neck surgery (24-10-2023)“…Background Biocompatibility and stability of three-dimensional printed polycaprolactone mesh grafts for nasal surgery are proven in both animal and human…”
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18
Decreased expression of CCL17 in the disrupted nasal polyp epithelium and its regulation by IL-4 and IL-5
Published in PloS one (10-05-2018)“…In airway epithelium, thymus and activation-regulated chemokine (CCL17) and macrophage-derived chemokine (CCL22) are induced by defective epithelial barriers…”
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Vitamin D attenuates myofibroblast differentiation and extracellular matrix accumulation in nasal polyp-derived fibroblasts through smad2/3 signaling pathway
Published in Scientific reports (04-08-2017)“…To investigate the potential role of vitamin D (1,25(OH) 2 D 3 ) in preventing the development of nasal polyps, we examined the effect of vitamin D on…”
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Baicalin Down-Regulates IL-1β-Stimulated Extracellular Matrix Production in Nasal Fibroblasts
Published in PloS one (21-12-2016)“…Baicalin, a Chinese herbal medicine, has anti-fibrotic and anti-inflammatory effects. The aims of present study were to investigate the effects of baicalin on…”
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