Search Results - "Park, Hyun Ji"
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1
Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms
Published in Nature communications (10-01-2020)“…Challenges in drug development of neurological diseases remain mainly ascribed to the blood–brain barrier (BBB). Despite the valuable contribution of animal…”
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2
Therapeutic use of extracellular mitochondria in CNS injury and disease
Published in Experimental neurology (01-02-2020)“…In the central nervous system (CNS), neuronal functionality is highly dependent on mitochondrial integrity and activity. In the context of a damaged or…”
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Tissue Adhesive Catechol-Modified Hyaluronic Acid Hydrogel for Effective, Minimally Invasive Cell Therapy
Published in Advanced functional materials (01-07-2015)“…Current hyaluronic acid (HA) hydrogel systems often cause cytotoxicity to encapsulated cells and lack the adhesive property required for effective localization…”
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4
High-resolution acoustophoretic 3D cell patterning to construct functional collateral cylindroids for ischemia therapy
Published in Nature communications (20-12-2018)“…The fabrication of functional tissues is essential for clinical applications such as disease treatment and drug discovery. Recent studies have revealed that…”
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Development of a reverse transcription-loop-mediated isothermal amplification as a rapid early-detection method for novel SARS-CoV-2
Published in Emerging microbes & infections (01-01-2020)“…The previous outbreaks of SARS-CoV and MERS-CoV have led researchers to study the role of diagnostics in impediment of further spread and transmission. With…”
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Attenuation of UVB-Induced Photo-Aging by Polyphenolic-Rich Spatholobus Suberectus Stem Extract Via Modulation of MAPK/AP-1/MMPs Signaling in Human Keratinocytes
Published in Nutrients (14-06-2019)“…It is well known that ultraviolet light activates mitogen-activated protein (MAP) kinase by increasing the reactive oxygen species (ROS) in the body, enhancing…”
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3D Printing of Poly‐ε‐Caprolactone (PCL) Auxetic Implants with Advanced Performance for Large Volume Soft Tissue Engineering
Published in Advanced functional materials (01-06-2023)“…A successful 3D printing of a novel 3D architected auxetic for large‐volume soft tissue engineering is reported. The 3D auxetic design is analyzed through…”
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Triboelectric Nanogenerator Accelerates Highly Efficient Nonviral Direct Conversion and In Vivo Reprogramming of Fibroblasts to Functional Neuronal Cells
Published in Advanced materials (Weinheim) (01-09-2016)“…Triboelectric nanogenerators (TENGs) can be an effective cell reprogramming platform for producing functional neuronal cells for therapeutic applications…”
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Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway
Published in Journal of neuroinflammation (11-12-2017)“…Methamphetamine (METH) is a commonly abused drug that may result in neurotoxic effects. Recent studies have suggested that involvement of neuroinflammatory…”
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10
Potential circadian effects on translational failure for neuroprotection
Published in Nature (London) (18-06-2020)“…Neuroprotectant strategies that have worked in rodent models of stroke have failed to provide protection in clinical trials. Here we show that the opposite…”
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Catechol-Functionalized Hyaluronic Acid Hydrogels Enhance Angiogenesis and Osteogenesis of Human Adipose-Derived Stem Cells in Critical Tissue Defects
Published in Biomacromolecules (13-06-2016)“…Over the last few decades, stem cell therapies have been highlighted for their potential to heal damaged tissue and aid in tissue reconstruction. However,…”
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A Surface‐Tailoring Method for Rapid Non‐Thermosensitive Cell‐Sheet Engineering via Functional Polymer Coatings
Published in Advanced materials (Weinheim) (01-04-2020)“…Cell sheet engineering, a technique utilizing a monolayer cell sheet, has recently emerged as a promising technology for scaffold‐free tissue engineering. In…”
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13
Cellulose nanocrystal-based materials: from liquid crystal self-assembly and glass formation to multifunctional thin films
Published in NPG Asia materials (01-01-2014)“…Cellulose nanocrystals (CNCs), produced by the acid hydrolysis of wood, cotton or other cellulose-rich sources, constitute a renewable nanosized raw material…”
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The Ethanolic Extract of Dictyopteris Divaricata Induces Apoptosis in Non-Small Cell Lung Cancer Cells by Inhibiting STAT3 Activity
Published in Nutrition and cancer (2024)“…Dictyopteris divaricata (DD) has been reported to exert diverse pharmacological activities, including anti-inflammatory, antioxidant, and anticancer effects…”
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Bidirectional relationship between cardiac extracellular matrix and cardiac cells in ischemic heart disease
Published in Stem cells (Dayton, Ohio) (01-12-2021)“…Ischemic heart diseases (IHDs), including myocardial infarction and cardiomyopathies, are a leading cause of mortality and morbidity worldwide. Cardiac‐derived…”
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Root Bark of Morus Alba L. Induced p53-Independent Apoptosis in Human Colorectal Cancer Cells by Suppression of STAT3 Activity
Published in Nutrition and cancer (28-05-2022)“…The root bark of Morus alba L. (MA) used in traditional oriental medicine exerts various bioactivities including anticancer effects. In this study, we…”
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Redox transformation of soil minerals and arsenic in arsenic-contaminated soil under cycling redox conditions
Published in Journal of hazardous materials (15-10-2019)“…•Mobility of As increases in the presence of Fe(II) under anoxic conditions•As mobility varies due to the dissolution or re-precipitation of Fe…”
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Root Extract of Trichosanthes kirilowii Suppresses Metastatic Activity of EGFR TKI-Resistant Human Lung Cancer Cells by Inhibiting Src-Mediated EMT
Published in Nutrition and cancer (2023)“…The roots of (TK) have been used in traditional oriental medicine for the treatment of respiratory diseases. In this study, we investigated whether an…”
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Effects of O-GlcNAcylation on functional mitochondrial transfer from astrocytes
Published in Journal of cerebral blood flow and metabolism (01-07-2021)“…Mitochondria may be transferred from cell to cell in the central nervous system and this process may help defend neurons against injury and disease. But how…”
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Hexane Fraction of Adenophora triphylla var. japonica Root Extract Inhibits Angiogenesis and Endothelial Cell-Induced Erlotinib Resistance in Lung Cancer Cells
Published in Molecules (Basel, Switzerland) (25-01-2024)“…The aim of this study was to investigate the anti-angiogenic effects of the hexane fraction of var. root extract (HAT) and its influence on the development of…”
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