Search Results - "Park, Hong Keun"

Regulation and function of SOX9 during cartilage development and regeneration by Song, Haengseok, Park, Keun-Hong

“…Chondrogenesis is a highly coordinated event in embryo development, adult homeostasis, and repair of the vertebrate cartilage. Fate decisions and…”
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Multimodal Magnetic Nanoclusters for Gene Delivery, Directed Migration, and Tracking of Stem Cells by Park, Ji Sun, Park, Wooram, Park, Sin‐jung, Larson, Andrew C., Kim, Dong‐Hyun, Park, Keun‐Hong

“…This study develops multimodal magnetic nanoclusters (M‐MNCs) for gene transfer, directed migration, and tracking of human mesenchymal stem cells (hMSCs). The…”
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In Situ Supramolecular Assembly and Modular Modification of Hyaluronic Acid Hydrogels for 3D Cellular Engineering by Park, Kyeng Min, Yang, Jeong-A, Jung, Hyuntae, Yeom, Junseok, Park, Ji Sun, Park, Keun-Hong, Hoffman, Allan S, Hahn, Sei Kwang, Kim, Kimoon

“…A facile in situ supramolecular assembly and modular modification of biocompatible hydrogels were demonstrated using cucurbit[6]uril-conjugated hyaluronic acid…”
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Multi-modal transfection agent based on monodisperse magnetic nanoparticles for stem cell gene delivery and tracking by Park, Wooram, Yang, Han Na, Ling, Daishun, Yim, Hyeona, Kim, Kyoung Sub, Hyeon, Taeghwan, Na, Kun, Park, Keun-Hong

“…Abstract Directing the controlled differentiation and tracking of stem cells is essential to achieve successful stem cell therapy. In this work, we describe a…”
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Bone morphogenic protein-2 (BMP-2) loaded nanoparticles mixed with human mesenchymal stem cell in fibrin hydrogel for bone tissue engineering by Park, Keun-Hong, Kim, Hyemin, Moon, Sumi, Na, Kun

“…Recent tissue engineering efforts have been focused on the use of natural or synthetic matrices which combine the characteristics of biodegradable properties…”
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Sunflower-type nanogels carrying a quantum dot nanoprobe for both superior gene delivery efficacy and tracing of human mesenchymal stem cells by Park, Ji Sun, Yi, Se Won, Kim, Hye Jin, Kim, Seong Min, Shim, Sung Han, Park, Keun-Hong

“…Abstract Sunflower-type nanogels carrying the QD 655 nanoprobe can be used for both gene transfection and bioimaging of hMSCs. The entry of sunflower-type…”
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Magnesium hydroxide-incorporated PLGA composite attenuates inflammation and promotes BMP2-induced bone formation in spinal fusion by Bedair, Tarek M., Lee, Chang Kyu, Kim, Da-Seul, Baek, Seung-Woon, Bedair, Hanan M., Joshi, Hari Prasad, Choi, Un Yong, Park, Keun-Hong, Park, Wooram, Han, InBo, Han, Dong Keun

“…Spinal fusion has become a common surgical technique to join two or more vertebrae to stabilize a damaged spine; however, the rate of pseudarthrosis (failure…”
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Strategies for accelerating osteogenesis through nanoparticle-based DNA/mitochondrial damage repair by Kim, Hye Jin, Cho, Hui Bang, Lee, Sujin, Lyu, Jiyon, Kim, Hye-Ryoung, Lee, Sujeong, Park, Ji-In, Park, Keun-Hong

“…The efficiency of gene therapy is often dictated by the gene delivery system. Cationic polymers are essential elements of gene delivery systems. The relatively…”
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Melatonin loaded PLGA nanoparticles effectively ameliorate the in vitro maturation of deteriorated oocytes and the cryoprotective abilities during vitrification process by Lee, Sujin, Kim, Hye Jin, Cho, Hui Bang, Kim, Hye-Ryoung, Lee, Sujeong, Park, Ji-In, Park, Keun-Hong

“…Almost all cells can be exposed to stress, but oocytes, which are female germ cells, are particularly vulnerable to damage. In this study, melatonin, a…”
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Direct Conversion of Human Dermal Fibroblasts into Cardiomyocyte‐Like Cells Using CiCMC Nanogels Coupled with Cardiac Transcription Factors and a Nucleoside Drug by Kim, Hye Jin, Oh, Hyun Jyung, Park, Ji Sun, Lee, Jung Sun, Kim, Jae‐Hwan, Park, Keun‐Hong

“…Using direct conversion technology, normal adult somatic cells can be routinely switched from their original cell type into specific differentiated cell types…”
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The use of biodegradable PLGA nanoparticles to mediate SOX9 gene delivery in human mesenchymal stem cells (hMSCs) and induce chondrogenesis by Kim, Jae-Hwan, Park, Ji Sun, Yang, Han Na, Woo, Dae Gyun, Jeon, Su Yeon, Do, Hyun-Jin, Lim, Hye-Young, Kim, Jung Mo, Park, Keun-Hong

“…Abstract In stem cell therapy, transfection of specific genes into stem cells is an important technique to induce cell differentiation. To perform gene…”
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Chondrogenic potential of stem cells derived from amniotic fluid, adipose tissue, or bone marrow encapsulated in fibrin gels containing TGF-β3 by Park, Ji Sun, Shim, Myung-Sun, Shim, Sung Han, Yang, Han Na, Jeon, Su Yeon, Woo, Dae Gyun, Lee, Dong Ryul, Yoon, Tae Ki, Park, Keun-Hong

“…Abstract In this study, several types of hMSCs, derived from bone marrow, adipose tissue, or amniotic fluid, were encapsulated in a fibrin hydrogel mixed with…”
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Comparison of the Clinical Outcomes of Single- and Double-row Repairs in Rotator Cuff Tears by Park, Jin-Young, Lhee, Sang-Hoon, Choi, Jin-Hyung, Park, Hong-Keun, Yu, Je-Wook, Seo, Joong-Bae

“…Background: Although research has demonstrated the superiority of double-row rotator cuff repair over single-row methods from a biological and mechanical point…”
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Improved mechanical and biological properties of biodegradable thinner poly(l-lactic acid) tubes by bi-directional drawing by Han, Ginam, Bedair, Tarek M., Kim, Dae Hwan, Park, Keun-Hong, Park, Wooram, Han, Dong Keun

“…Drawbacks in the commercially available fully biodegradable polymeric stents: (I) Thick stent struts suffer from delayed re-endothelialization and high risk of…”
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Gene expression profiling of chondrogenic differentiation by dexamethasone-conjugated polyethyleneimine with SOX trio genes in stem cells by Yi, Se Won, Kim, Hye Jin, Oh, Hyun Jyung, Shin, Heejun, Lee, Jung Sun, Park, Ji Sun, Park, Keun-Hong

“…During differentiation of stem cells, it is recognized that molecular mechanisms of transcription factors manage stem cells towards the intended lineage. In…”
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Osteogenic differentiation of human mesenchymal stem cells using RGD-modified BMP-2 coated microspheres by Park, Ji S, Yang, Han N, Jeon, Su Y, Woo, Dae G, Na, Kun, Park, Keun-Hong

“…Abstract Micro-structured scaffolds formed with poly(lactic- co -glycolic acid) (PLGA) microspheres were composed of adhesion molecules and growth factors…”
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Multiply clustered gold-based nanoparticles complexed with exogenous pDNA achieve prolonged gene expression in stem cells by Yi, Se Won, Park, Ji Sun, Kim, Hye Jin, Lee, Jung Sun, Woo, Dae Gyun, Park, Keun-Hong

“…Development of a stable and prolonged gene delivery system is a key goal in the gene therapy field. To this end, we designed and fabricated a gene delivery…”
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The use of injectable, thermosensitive poly(organophosphazene)–RGD conjugates for the enhancement of mesenchymal stem cell osteogenic differentiation by Chun, ChangJu, Lim, Hye Jin, Hong, Ki-Yun, Park, Keun-Hong, Song, Soo-Chang

“…Abstract An injectable and thermosensitive poly(organophosphazene)–RGD conjugate to enhance functionality was synthesized by a covalent amide linkage between a…”
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Efficient CRISPR-Cas9-based knockdown of RUNX2 to induce chondrogenic differentiation of stem cells by Kim, Hye Jin, Park, Jong Min, Lee, Sujin, Cho, Hui Bang, Park, Ji-In, Kim, Jae-Hwan, Park, Ji Sun, Park, Keun-Hong

“…The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 system recognizes and deletes specific nucleotide sequences in cells for gene…”
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Effect of growth factors on chondrogenic differentiation of rabbit mesenchymal cells embedded in injectable hydrogels by Park, Keun Hong, Na, Kun

“…In this study, a hydrogel scaffold of poly(NiPAAm-co-AAc) was utilized as an injectable delivery carrier containing cell and growth factors for engineering of…”
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