Search Results - "Park, Eunice"

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression by Brady, Colleen A., Jiang, Dadi, Mello, Stephano S., Johnson, Thomas M., Jarvis, Lesley A., Kozak, Margaret M., Broz, Daniela Kenzelmann, Basak, Shashwati, Park, Eunice J., McLaughlin, Margaret E., Karnezis, Anthony N., Attardi, Laura D.

“…The molecular basis for p53-mediated tumor suppression remains unclear. Here, to elucidate mechanisms of p53 tumor suppression, we use knockin mice expressing…”
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Examining aid fragmentation and collaboration opportunities in Cambodia's health sector by Lee, Suyeon, Park, Eunice Y

“…Cambodia's health sector faces significant challenges exacerbated by aid fragmentation, where development aid is dispersed among numerous small, uncoordinated…”
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Publisher Correction: Examining aid fragmentation and collaboration opportunities in Cambodia's health sector by Lee, Suyeon, Park, Eunice Y

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H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers by Seiler, Michael, Yoshimi, Akihide, Darman, Rachel, Chan, Betty, Keaney, Gregg, Thomas, Michael, Agrawal, Anant A, Caleb, Benjamin, Csibi, Alfredo, Sean, Eckley, Fekkes, Peter, Karr, Craig, Klimek, Virginia, Lai, George, Lee, Linda, Kumar, Pavan, Lee, Stanley Chun-Wei, Liu, Xiang, Mackenzie, Crystal, Meeske, Carol, Mizui, Yoshiharu, Padron, Eric, Park, Eunice, Pazolli, Ermira, Peng, Shouyong, Prajapati, Sudeep, Taylor, Justin, Teng, Teng, Wang, John, Warmuth, Markus, Yao, Huilan, Yu, Lihua, Zhu, Ping, Abdel-Wahab, Omar, Smith, Peter G, Buonamici, Silvia

“…The small molecule H3B-8800 selectively modulates RNA splicing to preferentially kill tumor cells bearing mutations in genes encoding spliceosome components…”
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Experience With Hydroxychloroquine and Azithromycin in the Coronavirus Disease 2019 Pandemic: Implications for QT Interval Monitoring by Ramireddy, Archana, Chugh, Harpriya, Reinier, Kyndaron, Ebinger, Joseph, Park, Eunice, Thompson, Michael, Cingolani, Eugenio, Cheng, Susan, Marban, Eduardo, Albert, Christine M, Chugh, Sumeet S

“…Background Despite a lack of clinical evidence, hydroxychloroquine and azithromycin are being administered widely to patients with verified or suspected…”
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Antibiotic Sensitivity Profiles Determined with an Escherichia coli Gene Knockout Collection: Generating an Antibiotic Bar Code by LIU, Anne, TRAN, Lillian, BECKET, Elinne, LEE, Kim, CHINN, Laney, PARK, Eunice, TRAN, Katherine, MILLER, Jeffrey H

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Harnessing the Electronic Medical Record to Improve the Utilization of Ultrasound Screening for Abdominal Aortic Aneurysms by Park, Eunice M., Yoneoka, Grant M., Yoon, Hyo-Chun

“…The US Preventive Services Task Force recommends one-time ultrasound screening to detect abdominal aortic aneurysms (AAAs) in male smokers. Despite this…”
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H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma by Joshi, Jaya Julie, Coffey, Heather, Corcoran, Erik, Tsai, Jennifer, Huang, Chia-Ling, Ichikawa, Kana, Prajapati, Sudeep, Hao, Ming-Hong, Bailey, Suzanna, Wu, Jeremy, Rimkunas, Victoria, Karr, Craig, Subramanian, Vanitha, Kumar, Pavan, MacKenzie, Crystal, Hurley, Raelene, Satoh, Takashi, Yu, Kun, Park, Eunice, Rioux, Nathalie, Kim, Amy, Lai, Weidong G, Yu, Lihua, Zhu, Ping, Buonamici, Silvia, Larsen, Nicholas, Fekkes, Peter, Wang, John, Warmuth, Markus, Reynolds, Dominic J, Smith, Peter G, Selvaraj, Anand

“…Activation of the fibroblast growth factor receptor FGFR4 by FGF19 drives hepatocellular carcinoma (HCC), a disease with few, if any, effective treatment…”
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Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators by Aird, Daniel, Teng, Teng, Huang, Chia-Ling, Pazolli, Ermira, Banka, Deepti, Cheung-Ong, Kahlin, Eifert, Cheryl, Furman, Craig, Wu, Zhenhua Jeremy, Seiler, Michael, Buonamici, Silvia, Fekkes, Peter, Karr, Craig, Palacino, James, Park, Eunice, Smith, Peter G., Yu, Lihua, Mizui, Yoshiharu, Warmuth, Markus, Chicas, Agustin, Corson, Laura, Zhu, Ping

“…Dysregulation of RNA splicing by spliceosome mutations or in cancer genes is increasingly recognized as a hallmark of cancer. Small molecule splicing…”
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Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex by Teng, Teng, Tsai, Jennifer HC, Puyang, Xiaoling, Seiler, Michael, Peng, Shouyong, Prajapati, Sudeep, Aird, Daniel, Buonamici, Silvia, Caleb, Benjamin, Chan, Betty, Corson, Laura, Feala, Jacob, Fekkes, Peter, Gerard, Baudouin, Karr, Craig, Korpal, Manav, Liu, Xiang, T. Lowe, Jason, Mizui, Yoshiharu, Palacino, James, Park, Eunice, Smith, Peter G., Subramanian, Vanitha, Wu, Zhenhua Jeremy, Zou, Jian, Yu, Lihua, Chicas, Agustin, Warmuth, Markus, Larsen, Nicholas, Zhu, Ping

“…Pladienolide, herboxidiene and spliceostatin have been identified as splicing modulators that target SF3B1 in the SF3b subcomplex. Here we report that PHF5A,…”
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Self-reported hearing loss and health during a pandemic: Findings from a cross-sectional analysis using a 2021 household survey by Park, Eunice Y., Nelson-Bakkum, Erin R., Schultz, Amy A., Dillard, Lauren K.

“…The COVID-19 pandemic differentially impacted individuals with hearing loss, likely in part due to increased communication difficulties from masking, a…”
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Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis by Beaudry, Veronica G, Jiang, Dadi, Dusek, Rachel L, Park, Eunice J, Knezevich, Stevan, Ridd, Katie, Vogel, Hannes, Bastian, Boris C, Attardi, Laura D

“…Dysregulated cell-cell adhesion plays a critical role in epithelial cancer development. Studies of human and mouse cancers have indicated that loss of adhesion…”
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Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages by Jiang, Dadi, Brady, Colleen A, Johnson, Thomas M, Lee, Eunice Y, Park, Eunice J, Scott, Matthew P, Attardi, Laura D

“…Over half of all human cancers, of a wide variety of types, sustain mutations in the p53 tumor suppressor gene. Although p53 limits tumorigenesis through the…”
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Regulation of ion channel localization and phosphorylation by neuronal activity by Misonou, Hiroaki, Mohapatra, Durga P, Park, Eunice W, Leung, Victor, Zhen, Dongkai, Misonou, Kaori, Anderson, Anne E, Trimmer, James S

“…Voltage-dependent Kv2.1 K(+) channels, which mediate delayed rectifier Kv currents (I(K)), are expressed in large clusters on the somata and dendrites of…”
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Seasonal COVID-19 surge related hospital volumes and case fatality rates by Ebinger, Joseph E, Lan, Roy, Driver, Matthew, Sun, Nancy, Botting, Patrick, Park, Eunice, Davis, Tod, Minissian, Margo B, Coleman, Bernice, Riggs, Richard, Roberts, Pamela, Cheng, Susan

“…Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by…”
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Sense of community and mental health: a cross-sectional analysis from a household survey in Wisconsin by Park, Eunice Y, Oliver, Thomas R, Peppard, Paul E, Malecki, Kristen C

“…In the USA, one in five adults live with a mental illness, and researchers have estimated that nearly half of the population will have a mental illness over…”
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The diagnostic and prognostic utility of positron emission tomography/computed tomography‐based follow‐up after radiotherapy for head and neck cancer by Kao, Johnny, Vu, Ha Linh, Genden, Eric M., Mocherla, Bharat, Park, Eunice E., Packer, Stuart, Som, Peter M., Kostakoglu, Lale

“…BACKGROUND: The detection of subclinical head and neck cancer recurrence or a second primary tumor may improve survival. In the current study, the authors…”
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Systems Thinking Is Vital to Long-Term Equitable COVID-19 Response and Recovery in Wisconsin by Davis, Sarah, Park, Eunice Y, Morgen, Maria, Khan, Baila, Donovan, Kylie, Kaur, Manpreet, Hackett, Margaret B

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Improvement in the detection of locoregional recurrence in head and neck malignancies: F-18 fluorodeoxyglucose-positron emission tomography/computed tomography compared to high-resolution contrast-enhanced computed tomography and endoscopic examination by Rangaswamy, Balasubramanya, Fardanesh, M. Reza, Genden, Eric M., Park, Eunice E., Fatterpekar, Girish, Patel, Zara, Kim, Jongho, Som, Peter M., Kostakoglu, Lale

“…Objectives/Hypothesis To compare the diagnostic efficacy of positron emission tomography (PET) with F‐18 fluorodeoxyglucose (FDG‐PET)/computed tomography (CT)…”
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E-cigarette Use Among Middle and High School Students — United States, 2020 by Wang, Teresa W, Neff, Linda J, Park-Lee, Eunice, Ren, Chunfeng, Cullen, Karen A, King, Brian A

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