Search Results - "Park, Chun–Woong"

Preparation of inhalable N-acetylcysteine-loaded magnetite chitosan microparticles for nitrate adsorption in particulate matter by Oh, Dong–Won, Kang, Ji–Hyun, Kim, Young–Jin, Na, Sang-Beom, Kwan Kwon, Taek, Kim, Seungsu, Hwan Shin, Dae, Jie, Gao, Shin, Myoung-Sook, Sung Kang, Ki, Kim, Ju–Young, Kim, Dong–Wook, Park, Chun–Woong

“…This new approach for adsorption and elimination of toxic substances entering the lung represents an alternative defense mechanism against exposure to nitrates…”
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Characterization of Channeling Effects Applied to Extended-Release Matrix Tablets Containing Pirfenidone by Kang, Ji-hyun, Yoo, Seung-Dong, Han, Ki-Hun, Jeong, So-Jeong, Lee, Hyo-Jung, Yoo, Je Hwa, Shin, Dae Hwan, Kim, Dong-Wook, Park, Eun-Seok, Park, Chun-Woong

“…Pirfenidone (PRF) is an anti-fibrotic agent that has been approved by the Food and Drug Administration (FDA) for the treatment of mild to moderate idiopathic…”
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Advanced spray-dried design, physicochemical characterization, and aerosol dispersion performance of vancomycin and clarithromycin multifunctional controlled release particles for targeted respiratory delivery as dry powder inhalation aerosols by Park, Chun-Woong, Li, Xiaojian, Vogt, Frederick G., Hayes, Don, Zwischenberger, Joseph B., Park, Eun-Seok, Mansour, Heidi M.

“…Respirable microparticles/nanoparticles of the antibiotics vancomycin (VCM) and clarithromycin (CLM) were successfully designed and developed by novel organic…”
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Evaluation of the Physicochemical Properties, Pharmacokinetics, and In Vitro Anticancer Effects of Docetaxel and Osthol Encapsulated in Methoxy Poly(ethylene glycol)- b -Poly(caprolactone) Polymeric Micelles by Jo, Min Jeong, Lee, Yu Jin, Park, Chun-Woong, Chung, Youn Bok, Kim, Jin-Seok, Lee, Mi Kyeong, Shin, Dae Hwan

“…Docetaxel (DTX), a taxane-based anticancer drug, and osthol (OTH), a coumarin-derivative compound, have shown anticancer effects against different types of…”
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Revolutionizing technologies of nanomicelles for combinatorial anticancer drug delivery by Jo, Min Jeong, Jin, Ik Sup, Park, Chun-Woong, Hwang, Bang Yeon, Chung, Youn Bok, Kim, Jin-Seok, Shin, Dae Hwan

“…Insufficient efficacy of current single drug therapy of cancers have led to the advancement of combination drug-loaded formulations. Specifically, polymeric…”
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Optimization and Pharmacokinetic Evaluation of Synergistic Fenbendazole and Rapamycin Co-Encapsulated in Methoxy Poly(Ethylene Glycol)-b-Poly(Caprolactone) Polymeric Micelles by Shin, Hee Ji, Jo, Min Jeong, Jin, Ik Sup, Park, Chun-Woong, Kim, Jin-Seok, Shin, Dae Hwan

“…Purpose: We aimed to develop a nanocarrier formulation incorporating fenbendazole (FEN) and rapamycin (RAPA) with strong efficacy against A549 cancer cells. As…”
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Evaluation of pH-Sensitive Polymeric Micelles Using Citraconic Amide Bonds for the Co-Delivery of Paclitaxel, Etoposide, and Rapamycin by Jo, Min Jeong, Shin, Hee Ji, Yoon, Moon Sup, Kim, Seo Yeon, Jin, Chae Eun, Park, Chun-Woong, Kim, Jin-Seok, Shin, Dae Hwan

“…Paclitaxel (PTX), etoposide (ETP), and rapamycin (RAPA) have different mechanisms, allowing multiple pathways to be targeted simultaneously, effectively…”
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Solid-state characterization and amorphous form identification in a small molecule by Seok, Su Hyun, Kim, Ju-Young, Park, Chun-Woong, Rhee, Yun-Seok, Park, Eun-Seok

“…Amorphous form and its characterization using a wide variety of analytical techniques have been known for decades. However, there is no single superior method…”
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Physicochemical, Pharmacokinetic, and Toxicity Evaluation of Soluplus® Polymeric Micelles Encapsulating Fenbendazole by Jin, Ik Sup, Jo, Min Jeong, Park, Chun-Woong, Chung, Youn Bok, Kim, Jin-Seok, Shin, Dae Hwan

“…Fenbendazole (FEN), a broad-spectrum benzimidazole anthelmintic, suppresses cancer cell growth through various mechanisms but has low solubility and achieves…”
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In vivo pharmacokinetic and pharmacodynamic study of co-spray-dried inhalable pirfenidone microparticles in rats by Kang, Ji-Hyun, Yang, Min-Seok, Kim, Dong-Wook, Park, Chun-Woong

“…Pirfenidone (PRF) is the first FDA-approved API in the treatment of idiopathic pulmonary fibrosis (IPF). However, PRF induces serious side effects, such as…”
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Synergistic Encapsulation of Paclitaxel and Sorafenib by Methoxy Poly(Ethylene Glycol)- b -Poly(Caprolactone) Polymeric Micelles for Ovarian Cancer Therapy by Jin, Chae Eun, Yoon, Moon Sup, Jo, Min Jeong, Kim, Seo Yeon, Lee, Jae Min, Kang, Su Jeong, Park, Chun-Woong, Kim, Jin-Seok, Shin, Dae Hwan

“…Ovarian cancer has a high mortality rate due to difficult detection at an early stage. It is necessary to develop a novel anticancer treatment that…”
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Preliminary bioequivalence of an oral integrating film formulation containing meloxicam with a suspension formulation in beagle dogs by Park, Jong‐Shik, Kim, Sungmin, Lee, Jaeyeon, Choi, Jae‐Cheol, Kim, YoungAh, Park, Chun‐Woong, Lee, Soohan

“…The oral disintegrating film (ODF) has advantages over suspension and tablet. These include convenience of administration, patient compliance, and accurate…”
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Recent Advances and Challenges in Controlling the Spatiotemporal Release of Combinatorial Anticancer Drugs from Nanoparticles by Yoon, Moon Sup, Lee, Yu Jin, Shin, Hee Ji, Park, Chun-Woong, Han, Sang-Bae, Jung, Jae-Kyung, Kim, Jin-Seok, Shin, Dae Hwan

“…To overcome cancer, various chemotherapeutic studies are in progress; among these, studies on nano-formulated combinatorial drugs (NFCDs) are being actively…”
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The Effect of Particle Size and Surface Roughness of Spray-Dried Bosentan Microparticles on Aerodynamic Performance for Dry Powder Inhalation by Kwon, Yong-Bin, Kang, Ji-Hyun, Han, Chang-Soo, Kim, Dong-Wook, Park, Chun-Woong

“…The purpose of this study was to prepare spray dried bosentan microparticles for dry powder inhaler and to characterize its physicochemical and aerodynamic…”
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Preparation and Evaluation of Inhalable Amifostine Microparticles Using Wet Ball Milling by Choi, Jae-Cheol, Kang, Ji-Hyun, Kim, Dong-Wook, Park, Chun-Woong

“…The conventional dosage form of Ethyol (amifostine), a sterile lyophilized powder, involves reconstituting it with 9.7 mL of sterile 0.9% sodium chloride in…”
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Novel Esomeprazole Magnesium-Loaded Dual-Release Mini-Tablet Polycap: Formulation, Optimization, Characterization, and In Vivo Evaluation in Beagle Dogs by Kwon, Taek Kwan, Kang, Ji-Hyun, Kim, Jae Ho, Kim, Yong-Il, Kim, Dong-Wook, Park, Chun-Woong

“…Esomeprazole magnesium (EMP) is a proton pump inhibitor (PPI) that reduces acid secretion. EMP has a short plasma half-life (approximately 1.3 h); hence,…”
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Corrugated surface microparticles with chitosan and levofloxacin for improved aerodynamic performance by Han, Chang-Soo, Kang, Ji-Hyun, Park, Eun hye, Lee, Hyo-Jung, Jeong, So-Jeong, Kim, Dong-Wook, Park, Chun-Woong

“…Corrugated surface microparticles comprising levofloxacin (LEV), chitosan and organic acid were prepared using the 3-combo spray drying method. The amount and…”
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Preparation and characterization of metformin hydrochloride controlled-release tablet using fatty acid coated granules by Kang, Ji-Hyun, Chun, Myung-Hee, Cho, Mi-Seo, Kwon, Yong-Bin, Choi, Jae-Cheol, Kim, Dong-Wook, Park, Chun-Woong, Park, Eun-Seok

“…Metformin hydrochloride (MFM) is often used as a controlled-release (CR) tablet to reduce dosing frequency. However, the MFM CR tablet contains significant…”
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Formulation and Evaluation of a Self-microemulsifying Drug Delivery System Containing Bortezomib by Hong, Eon-Pyo, Kim, Ju-Young, Kim, Su-Hyeon, Hwang, Kyu-Mok, Park, Chun-Woong, Lee, Hyo-Jung, Kim, Dong-Wook, Weon, Kwon-Yeon, Jeong, Seo Young, Park, Eun-Seok

“…The purposes of the present study were to develop a self-microemulsifying drug delivery system (SMEDDS) containing bortezomib, a proteasome inhibitor. The…”
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Preparation and In Vivo Evaluation of a Lidocaine Self-Nanoemulsifying Ointment with Glycerol Monostearate for Local Delivery by Kang, Ji-Hyun, Yoo, Kwang-Hwi, Park, Hyo-Young, Hyun, Seung-Min, Han, Sang-Duk, Kim, Dong-Wook, Park, Chun-Woong

“…Lidocaine, a commonly used local anesthetic, has recently been developed into a number of ointment products to treat hemorrhoids. This study examined its…”
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