Search Results - "Park, ChangHo"

Deep resequencing of 131 Crohn's disease associated genes in pooled DNA confirmed three reported variants and identified eight novel variants by Hong, Sung Noh, Park, Changho, Park, Soo Jung, Lee, Chang Kyun, Ye, Byong Duk, Kim, You Sun, Lee, Seungbok, Chae, Jeesoo, Kim, Jong-Il, Kim, Young-Ho

“…Genome wide association studies (GWAS) and meta-analyses for Crohn's disease (CD) have not fully explained the heritability of CD, suggesting that additional…”
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Prediction of lung cancer using novel biomarkers based on microbiome profiling of bronchoalveolar lavage fluid by Kim, Gihyeon, Park, Changho, Yoon, Young Kwang, Park, Dongil, Lee, Jeong Eun, Lee, Dahye, Sun, Pureum, Park, Shinyoung, Yun, Changhee, Kang, Da Hyun, Chung, Chaeuk

“…There is an unmet need for biomarkers for the diagnosis of lung cancer and decision criteria for lung biopsy. We comparatively investigated the lung…”
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Endophytic Trichoderma citrinoviride isolated from mountain-cultivated ginseng (Panax ginseng) has great potential as a biocontrol agent against ginseng pathogens by Park, Young-Hwan, Chandra Mishra, Ratnesh, Yoon, Sunkyung, Kim, Hoki, Park, Changho, Seo, Sang-Tae, Bae, Hanhong

“…Ginseng (Panax ginseng Meyer) is an invaluable medicinal plant containing various bioactive metabolites (e.g., ginsenosides). Owing to its long cultivation…”
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Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer by Park, Hansoo, Cho, Sung-Yup, Kim, Hyerim, Na, Deukchae, Han, Jee Yun, Chae, Jeesoo, Park, Changho, Park, Ok-Kyoung, Min, Seoyeon, Kang, Jinjoo, Choi, Boram, Min, Jimin, Kwon, Jee Young, Suh, Yun-Suhk, Kong, Seong-Ho, Lee, Hyuk-Joon, Liu, Edison T, Kim, Jong-Il, Kim, Sunghoon, Yang, Han-Kwang, Lee, Charles

“…Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide. Recent high-throughput analyses of genomic alterations revealed several…”
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Bifidobacterial carbohydrate/nucleoside metabolism enhances oxidative phosphorylation in white adipose tissue to protect against diet-induced obesity by Kim, Gihyeon, Yoon, Youngmin, Park, Jin Ho, Park, Jae Won, Noh, Myung-Guin, Kim, Hyun, Park, Changho, Kwon, Hyuktae, Park, Jeong-Hyeon, Kim, Yena, Sohn, Jinyoung, Park, Shinyoung, Kim, Hyeonhui, Im, Sun-Kyoung, Kim, Yeongmin, Chung, Ha Yung, Nam, Myung Hee, Kwon, Jee Young, Kim, Il Yong, Kim, Yong Jae, Baek, Ji Hyeon, Kim, Hak Su, Weinstock, George M, Cho, Belong, Lee, Charles, Fang, Sungsoon, Park, Hansoo, Seong, Je Kyung

“…Comparisons of the gut microbiome of lean and obese humans have revealed that obesity is associated with the gut microbiome plus changes in numerous…”
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Practical prediction model of the clinical response to programmed death-ligand 1 inhibitors in advanced gastric cancer by Noh, Myung-Giun, Yoon, Youngmin, Kim, Gihyeon, Kim, Hyun, Lee, Eulgi, Kim, Yeongmin, Park, Changho, Lee, Kyung-Hwa, Park, Hansoo

“…The identification of predictive biomarkers or models is necessary for the selection of patients who might benefit the most from immunotherapy. Seven…”
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Japanese activities of the R&D on silicon carbide composites in the broader approach period and beyond by Nozawa, Takashi, Ozawa, Kazumi, Park, ChangHo, Park, Joon-Soo, Kohyama, Akira, Hasegawa, Akira, Nogami, Shuhei, Hinoki, Tatsuya, Kondo, Sosuke, Yano, Toyohiko, Shibayama, Tamaki, Tsuchiya, Bun, Shikama, Tatsuo, Nagata, Shinji, Tanaka, Teruya, Iwakiri, Hirotomo, Yamamoto, Yasushi, Konishi, Satoshi, Kasada, Ryuta, Kondo, Masatoshi, Kunugi, Tomoaki, Yokomine, Takehiko, Ueki, Yoshitaka, Okubo, Nariaki, Taguchi, Tomitsugu, Tanigawa, Hiroyasu

“…The R&D on SiC/SiC composites under the broader approach (BA) activities between Japan and the EU for fusion DEMO developed a fundamental database of…”
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Spermidine-induced recovery of human dermal structure and barrier function by skin microbiome by Kim, Gihyeon, Kim, Misun, Kim, Minji, Park, Changho, Yoon, Youngmin, Lim, Doo-Hyeon, Yeo, Hyeonju, Kang, Seunghyun, Lee, Yeong-Geun, Beak, Nam-In, Lee, Jongsung, Kim, Sujeong, Kwon, Jee Young, Choi, Won Woo, Lee, Charles, Yoon, Kyoung Wan, Park, Hansoo, Lee, Dong-Geol

“…An unbalanced microbial ecosystem on the human skin is closely related to skin diseases and has been associated with inflammation and immune responses…”
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Endophytic Trichoderma citrinoviride isolated from mountain-cultivated ginseng (Panax ginseng) has great potential as a biocontrol agent against ginseng pathogens by Park, Young-Hwan, Mishra, Ratnesh Chandra, Yoon, Sunkyung, Kim, Hoki, Park, Changho, Seo, Sang-Tae, Bae, Hanhong

“…Background: Ginseng (Panax ginseng Meyer) is an invaluable medicinal plant containing various bioactive metabolites (e.g., ginsenosides). Owing to its long…”
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Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice by Lee, Se-Hoon, Cho, Sung-Yup, Yoon, Youngmin, Park, Changho, Sohn, Jinyoung, Jeong, Jin-Ju, Jeon, Bu-Nam, Jang, Mongjoo, An, Choa, Lee, Suro, Kim, Yun Yeon, Kim, Gihyeon, Kim, Sujeong, Kim, Yunjae, Lee, Gwang Bin, Lee, Eun Ju, Kim, Sang Gyun, Kim, Hong Sook, Kim, Yeongmin, Kim, Hyun, Yang, Hyun-Suk, Kim, Sarang, Kim, Seonggon, Chung, Hayung, Moon, Myeong Hee, Nam, Myung Hee, Kwon, Jee Young, Won, Sungho, Park, Joon-Suk, Weinstock, George M., Lee, Charles, Yoon, Kyoung Wan, Park, Hansoo

“…The gut microbiome can influence the development of tumours and the efficacy of cancer therapeutics 1 – 5 ; however, the multi-omics characteristics of…”
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The effect of wall flow velocity on compatibility of high-purity SiC materials with liquid Pb-Li alloy by rotating disc testing for 3000 h up to 900 °C by Park, ChangHo, Nozawa, Takashi, Kasada, Ryuta, Tosti, Silvano, Konishi, Satoshi, Tanigawa, Hiroyasu

“…The lead-lithium (Pb-Li) alloy is considered as a coolant and a tritium breeder for fusion reactor blanket systems. One of the critical requirements in…”
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Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1 by Kim, Seo Yihl, Chae, Chang Woo, Lee, Hyun Jik, Jung, Young Hyun, Choi, Gee Euhn, Kim, Jun Sung, Lim, Jae Ryong, Lee, Joo Eun, Cho, Ji Hyeon, Park, Hansoo, Park, Changho, Han, Ho Jae

“…The gut–brain axis is currently being studied as a therapeutic strategy for neurological diseases, especially Alzheimer’s disease (AD). Obesity results in the…”
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Abstract 7522: Association between the CNTN4 expression and responsiveness to pembrolizumab in gastric cancer by Cha, Mi Young, Kim, Gihyeon, Park, Changho, Jeon, Bu-Nam, Park, Kyung Mi, Park, Hansoo, Ock, Chan-Young

“…Even though numerous strategies for controlling malignant tumors have been established with immunotherapies, a solution for non-favorable responses to…”
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Dysregulated Wnt signalling and recurrent mutations of the tumour suppressor RNF43 in early gastric carcinogenesis by Min, Byung-Hoon, Hwang, Jinha, Kim, Nayoung KD, Park, Gibeom, Kang, So Young, Ahn, Sangjeong, Ahn, Soomin, Ha, Sang Yun, Lee, Yun Kyung, Kushima, Ryoji, Van Vrancken, Michael, Kim, Min Jung, Park, Changho, Park, Ha Young, Chae, Jeesoo, Jang, Se Song, Kim, Sung Jin, Kim, Young-Ho, Kim, Jong-Il, Kim, Kyoung-Mee

“…Several recurrent mutations and epigenetic changes have been identified in advanced gastric cancer, but the genetic alterations associated with early gastric…”
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Interaction between surface behavior and inner flow pattern of liquid Li jet for fusion neutron sources by Hoashi, Eiji, Fujii, Yasuhiro, Yamada, Shunya, Okita, Takafumi, Kondo, Hiroo, Park, Chang Ho, Nakamura, Makoto M., Ochiai, Kentaro, Kasugai, Atsushi

“…•MSGD model was introduced to LES as wall roughness model and this was applied to parallel plate flow of Li.•Vortices on rough wall keep finer structure than…”
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Overview of test modules for Advanced Fusion Neutron Source A-FNS by Sato, Satoshi, Nakamura, Makoto, Kwon, Saerom, Ohta, Masayuki, Park, ChangHo, Oyaidzu, Makoto, Ochiai, Kentaro, Kasugai, Atsushi, Sakamoto, Keishi, Ishida, Shinichi

“…•Establishment of basic specifications and concepts on the test modules for A-FNS.•Structural design on the test module taken into account the replacement with…”
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Verification of accuracy of contact-probe distance meter for lithium target of fusion neutron source by Okita, Takafumi, Entani, Shota, Watanabe, Kotaro, Higashi, Masahiro, Hoashi, Eiji, Kondo, Hiroo, Park, ChangHo, Nakamura, Makoto M, Ochiai, Kentaro, Kasugai, Atsushi

“…•Experiments for developing the Li target system in the Fusion Neutron Source (FNS).•Measurements of free-surface fluctuation using a non-contact laser-probe…”
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Contactin-4 suppresses antitumor T cell responses by engaging amyloid precursor protein by Jeon, Bu-Nam, Kim, Sujeong, Kim, Yunjae, Yu, Hyunkyung, Park, Changho, Kim, Gihyeon, Ha, Youngeun, Kim, Gyeong-Yeon, Kim, Hyunuk, Palucka, Karolina A, Lee, Charles, Cha, Miyoung, Park, Hansoo

“…Immune checkpoint inhibitors have substantial advanced tumor treatment, but their limited benefits and strong responses in only a subset of patients remain…”
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High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients by Cho, Sung-Yup, Park, Changho, Na, Deukchae, Han, Jee Yun, Lee, Jieun, Park, Ok-Kyoung, Zhang, Chengsheng, Sung, Chang Ohk, Moon, Hyo Eun, Kim, Yona, Kim, Jeong Hoon, Kim, Jong Jae, Khang, Shin Kwang, Nam, Do-Hyun, Choi, Jung Won, Suh, Yeon-Lim, Kim, Dong Gyu, Park, Sung Hye, Youn, Hyewon, Yun, Kyuson, Kim, Jong-Il, Lee, Charles, Paek, Sun Ha, Park, Hansoo

“…Gliosarcoma (GS) is a rare variant (2%) of glioblastoma (GBM) that poses clinical genomic challenges because of its poor prognosis and limited genomic…”
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Abstract 1868: Novel immune checkpoint inhibitor: In vivo and in vitro efficacy of anti-CNTN4 antibody, GENA-104A16 in the models with increased CNTN4 expression by Cha, Mi Young, Yu, Hyunkyung, Jeon, Bu-Nam, Ha, Youngeun, Kim, Hyunuk, Kim, Yunyeon, Chung, Joo-Yeon, Kim, Gihyeon, Park, Changho, Park, Kyung Mi, Park, Hansoo

“…We previously suggested that contactin 4 (CNTN4) negatively regulates T cell activity through binding with amyloid precursor protein on T cells. In addition,…”
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