Search Results - "Parisien, Mathieu"
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Direct Arylation Reactions Catalyzed by Pd(OH)2/C: Evidence for a Soluble Palladium Catalyst
Published in Journal of organic chemistry (16-09-2005)“…Palladium hydroxide on carbon (Pearlman's catalyst) effectively catalyzes direct arylation reactions of aryl iodides and bromides, providing excellent…”
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Biaryl Synthesis via Direct Arylation: Establishment of an Efficient Catalyst for Intramolecular Processes
Published in Journal of the American Chemical Society (04-08-2004)“…In this Communication, we describe direct arylation reactions with improved scope and catalyst activity for the intramolecular formation of biaryl compounds…”
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Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV‑1
Published in ACS medicinal chemistry letters (10-04-2014)“…An assay recapitulating the 3′ processing activity of HIV-1 integrase (IN) was used to screen the Boehringer Ingelheim compound collection. Hit-to-lead and…”
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Catalytic Direct Arylation with Aryl Chlorides, Bromides, and Iodides: Intramolecular Studies Leading to New Intermolecular Reactions
Published in Journal of the American Chemical Society (18-01-2006)“…A catalyst for the intramolecular direct arylation of a broad range of simple and heterocyclic arenes with aryl iodides, bromides, and chlorides has been…”
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Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus
Published in ACS medicinal chemistry letters (12-05-2016)“…A high-throughput screen based on a viral replication assay was used to identify inhibitors of the human cytomegalovirus. Using this approach, hit compound 1…”
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Catalyst development for the direct arylation of aryl chlorides, bromides and iodides
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Dissertation