Search Results - "Parisi, Michael"
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γ-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor
Published in Developmental cell (11-07-2022)“…Developing synapses mature through the recruitment of specific proteins that stabilize presynaptic and postsynaptic structure and function. Wnt ligands…”
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Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD
Published in Nature neuroscience (01-06-2019)“…An expanded GGGGCC hexanucleotide of more than 30 repeats (termed (G4C2) 30+ ) within C9orf72 is the most prominent mutation in familial frontotemporal…”
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Demasculinization of X chromosomes in the Drosophila genus
Published in Nature (08-11-2007)“…X chromosomes evolve differently from autosomes, but general governing principles have not emerged. For example, genes with male-biased expression are…”
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ESCRT disruption provides evidence against trans-synaptic signaling via extracellular vesicles
Published in The Journal of cell biology (02-09-2024)“…Extracellular vesicles (EVs) are released by many cell types, including neurons, carrying cargoes involved in signaling and disease. It is unclear whether EVs…”
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Author Correction: Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD
Published in Nature neuroscience (01-03-2023)Get full text
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SynLight: a bicistronic strategy for simultaneous active zone and cell labeling in the Drosophila nervous system
Published in G3 : genes - genomes - genetics (01-11-2023)“…Abstract At synapses, chemical neurotransmission mediates the exchange of information between neurons, leading to complex movement, behaviors, and stimulus…”
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A conditional strategy for cell-type-specific labeling of endogenous excitatory synapses in Drosophila
Published in Cell reports methods (22-05-2023)“…Chemical neurotransmission occurs at specialized contacts where neurotransmitter release machinery apposes neurotransmitter receptors to underlie circuit…”
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The exonuclease Nibbler regulates age‐associated traits and modulates piRNA length in Drosophila
Published in Aging cell (01-06-2015)“…Summary Nibbler (Nbr) is a 3′‐to‐5′ exonuclease that trims the 3′end of microRNAs (miRNAs) to generate different length patterns of miRNAs in Drosophila…”
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Lipid profiles of female and male Drosophila
Published in BMC research notes (15-06-2011)“…D. melanogaster is increasingly used as a lipid metabolism model, but the D. melanogaster metabolome is not well studied. A number of studies strongly suggest…”
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Functional Conservation for Lipid Storage Droplet Association among Perilipin, ADRP, and TIP47 (PAT)-related Proteins in Mammals,Drosophila, and Dictyostelium
Published in The Journal of biological chemistry (30-08-2002)“…Intracellular neutral lipid storage droplets are essential organelles of eukaryotic cells, yet little is known about the proteins at their surfaces or about…”
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Germline-dependent gene expression in distant non-gonadal somatic tissues of Drosophila
Published in BMC genomics (01-06-2010)“…Drosophila females commit tremendous resources to egg production and males produce some of the longest sperm in the animal kingdom. We know little about the…”
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Molecular Pathology of the MEN1 Gene
Published in Annals of the New York Academy of Sciences (01-04-2004)“…: Multiple endocrine neoplasia type 1 (MEN1), among all syndromes, causes tumors in the highest number of tissue types. Most of the tumors are hormone…”
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Antimicrobial Stewardship Practices in Outpatient Parenteral Antimicrobial Therapy Programs in the United States
Published in Open forum infectious diseases (01-07-2024)“…Abstract Background Outpatient parenteral antimicrobial therapy (OPAT) regimens typically prioritize ease of antimicrobial administration, tolerability,…”
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Global analysis of X-chromosome dosage compensation
Published in Journal of biology (London, England) (2006)“…Drosophila melanogaster females have two X chromosomes and two autosome sets (XX;AA), while males have a single X chromosome and two autosome sets (X;AA)…”
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The role of the hedgehog/patched signaling pathway in epithelial stem cell proliferation: from fly to human
Published in Cell research (01-03-1998)“…The hedgehog-patched (hh-ptc) intercellular signaling pathway has recently been shown to control the proliferation of epithelial stem cells in both Drosophila…”
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Axon Injury and Regeneration in the Adult Drosophila
Published in Scientific reports (27-08-2014)“…Neural regeneration is a fascinating process with profound impact on human health, such that defining biological and genetic pathways is of interest. Here we…”
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Constraint and turnover in sex-biased gene expression in the genus Drosophila
Published in Nature (08-11-2007)“…Both genome content and deployment contribute to phenotypic differences between species. Sex is the most important difference between individuals in a species…”
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Evidence for redundancy but not trans factor-cis element coevolution in the regulation of Drosophila Yp genes
Published in Genetics (Austin) (01-06-1999)“…In Drosophila melanogaster and the endemic Hawaiian species D. grimshawi three Yolk protein (Yp) genes are expressed in a similar sex- and tissue-specific…”
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