Search Results - "Parisi, Chiara"
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Tumor Extracellular Matrix Stiffness Promptly Modulates the Phenotype and Gene Expression of Infiltrating T Lymphocytes
Published in International journal of molecular sciences (30-05-2021)“…The immune system is a fine modulator of the tumor biology supporting or inhibiting its progression, growth, invasion and conveys the pharmacological treatment…”
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2
MicroRNAs: newcomers into the ALS picture
Published in CNS & neurological disorders drug targets (01-01-2015)“…Amyotrophic lateral sclerosis (ALS) causes neurodegeneration of both upper and lower motor neurons and progressive muscle impairment, atrophy and death within…”
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3
Brain derived neurotrophic factor (BDNF) expression is regulated by microRNAs miR-26a and miR-26b allele-specific binding
Published in PloS one (14-12-2011)“…Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays an essential role in neuronal development and plasticity. MicroRNA (miRNAs) are small…”
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4
M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b
Published in Mediators of Inflammation (01-01-2016)“…Amyotrophic lateral sclerosis (ALS) is a most frequently occurring and severe form of motor neuron disease, causing death within 3–5 years from diagnosis and…”
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5
Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis
Published in Disease models & mechanisms (01-09-2014)“…In recent years there has been an increasing awareness of the role of P2X7, a receptor for extracellular ATP, in modulating physiopathological mechanisms in…”
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6
Modulation of P2X7 Receptor during Inflammation in Multiple Sclerosis
Published in Frontiers in immunology (15-11-2017)“…Multiple sclerosis (MS) is characterized by macrophage accumulation and inflammatory infiltrates into the CNS contributing to demyelination. Because purinergic…”
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7
P2Y_(12) Receptor on the Verge of a Neuroinflammatory Breakdown
Published in Mediators of Inflammation (01-01-2014)“…In the CNS, neuroinflammation occurring during pathologies as amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) is the consequence of an…”
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8
Unusual Association of NF-κB Components in Tumor-Associated Macrophages (TAMs) Promotes HSPG2-Mediated Immune-Escaping Mechanism in Breast Cancer
Published in International journal of molecular sciences (18-07-2022)“…The cellular heterogeneity of the tumor environment of breast cancer (BC) is extremely complex and includes different actors such as neoplastic, stromal, and…”
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9
Very Early Involvement of Innate Immunity in Peripheral Nerve Degeneration in SOD1-G93A Mice
Published in Frontiers in immunology (20-11-2020)“…Recent preclinical and clinical evidence suggest that immune system has a role in the progression and prognosis of Amyotrophic Lateral Sclerosis (ALS), but the…”
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10
Small RNAs and tooth development: The role of microRNAs in tooth agenesis and impaction
Published in Journal of dental sciences (01-10-2024)“…Tooth development, or odontogenesis, is a complex process in which several molecular pathways play a key role. Recently, microRNAs, a class of approximately…”
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New kid on the block: does histamine get along with inflammation in amyotrophic lateral sclerosis?
Published in CNS & neurological disorders drug targets (01-01-2015)“…Results from amyotrophic lateral sclerosis (ALS) patients and pre-clinical studies strongly suggest that systemic and CNS-intrinsic immune activation plays a…”
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12
Corrigendum: Very Early Involvement of Innate Immunity in Peripheral Nerve Degeneration in SOD1-G93A Mice
Published in Frontiers in immunology (06-04-2021)“…[This corrects the article DOI: 10.3389/fimmu.2020.575792.]…”
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13
RACK1 is a ribosome scaffold protein for β-actin mRNA/ZBP1 complex
Published in PloS one (16-04-2012)“…In neurons, specific mRNAs are transported in a translationally repressed manner along dendrites or axons by transport ribonucleic-protein complexes called RNA…”
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14
Clemastine Confers Neuroprotection and Induces an Anti-Inflammatory Phenotype in SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
Published in Molecular neurobiology (2016)“…Mutations in the Cu 2+ /Zn 2+ superoxide dismutase 1 (SOD1) gene underlie 14–23 % of familial and 1–7 % of sporadic cases of amyotrophic lateral sclerosis…”
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15
Computational Modeling of Inhibitory Transsynaptic Signaling in Hippocampal and Cortical Neurons Expressing Intrabodies Against Gephyrin
Published in Frontiers in cellular neuroscience (16-06-2020)“…GABAergic transmission regulates neuronal excitability, dendritic integration of synaptic signals and oscillatory activity, thought to be involved in high…”
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16
The reverse transcription inhibitor abacavir shows anticancer activity in prostate cancer cell lines
Published in PloS one (03-12-2010)“…Transposable Elements (TEs) comprise nearly 45% of the entire genome and are part of sophisticated regulatory network systems that control developmental…”
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Ago1 and Ago2 differentially affect cell proliferation, motility and apoptosis when overexpressed in SH-SY5Y neuroblastoma cells
Published in FEBS letters (03-10-2011)“…► Ago1 overexpression has a tumor suppressor like behaviour in SH-SY5Y. ► Both Ago1 and Ago2 can affect differentiation in SH-SY5Y. ► p53 Levels are strongly…”
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Endothelial Reprogramming in Sports Traumatology: Role of the Widespread Neuro-Immuno-Endocrine-Endothelial System
Published in Applied sciences (01-01-2023)“…This paper deals with the role of the widespread neuro-immuno-endocrine-endothelial system in sport traumatology. The aim of this work is to see if sport or…”
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Short-Term Effects of Specific Sensorimotor Training on Postural Assessment in Healthy Individuals: A Pilot Study with a Randomized Placebo-Controlled Trial
Published in Journal of functional morphology and kinesiology (19-04-2023)“…It is well-known that sensorimotor training aims to increase the performance of the sensorimotor system to maintain an upright position. Through the use of a…”
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20
P2Y12 Receptor on the Verge of a Neuroinflammatory Breakdown
Published in Mediators of inflammation (01-01-2014)“…In the CNS, neuroinflammation occurring during pathologies as amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) is the consequence of an…”
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