Search Results - "Parish, L."

Clemens von Pirquet: Preeminent researcher, teacher, clinician and advocate by Walter, S, Parish, L C

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Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy by Javed, Ibrahim, Peng, Guotao, Xing, Yanting, Yu, Tianyu, Zhao, Mei, Kakinen, Aleksandr, Faridi, Ava, Parish, Clare L., Ding, Feng, Davis, Thomas P., Ke, Pu Chun, Lin, Sijie

“…Alzheimer’s disease (AD) is the most prevalent form of neurodegenerative disorders, yet no major breakthroughs have been made in AD human trials and the…”
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Hydrogel oxygen reservoirs increase functional integration of neural stem cell grafts by meeting metabolic demands by Wang, Y., Zoneff, E. R., Thomas, J. W., Hong, N., Tan, L. L., McGillivray, D. J., Perriman, A. W., Law, K. C. L., Thompson, L. H., Moriarty, N., Parish, C. L., Williams, R. J., Jackson, C. J., Nisbet, D. R.

“…Injectable biomimetic hydrogels have great potential for use in regenerative medicine as cellular delivery vectors. However, they can suffer from issues…”
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Disruption of CTCF-YY1-dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription by Pentland, Ieisha, Campos-León, Karen, Cotic, Marius, Davies, Kelli-Jo, Wood, C David, Groves, Ian J, Burley, Megan, Coleman, Nicholas, Stockton, Joanne D, Noyvert, Boris, Beggs, Andrew D, West, Michelle J, Roberts, Sally, Parish, Joanna L

“…The complex life cycle of oncogenic human papillomavirus (HPV) initiates in undifferentiated basal epithelial keratinocytes where expression of the E6 and E7…”
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Harnessing stem cells and biomaterials to promote neural repair by Bruggeman, K F, Moriarty, N, Dowd, E, Nisbet, D R, Parish, C L

“…With the limited capacity for self‐repair in the adult CNS, efforts to stimulate quiescent stem cell populations within discrete brain regions, as well as…”
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Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson’s Disease by Gantner, Carlos W., de Luzy, Isabelle R., Kauhausen, Jessica A., Moriarty, Niamh, Niclis, Jonathan C., Bye, Christopher R., Penna, Vanessa, Hunt, Cameron P.J., Ermine, Charlotte M., Pouton, Colin W., Kirik, Deniz, Thompson, Lachlan H., Parish, Clare L.

“…Dopaminergic neurons (DAns), generated from human pluripotent stem cells (hPSCs), are capable of functionally integrating following transplantation and have…”
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Pregnancy Outcomes Among Women with Intellectual and Developmental Disabilities by Mitra, Monika, PhD, Parish, Susan L., PhD, MSW, Clements, Karen M., ScD, MPH, Cui, Xiaohui, ScD, Diop, Hafsatou, MD, MPH

“…Background There is currently no population-based research on the maternal characteristics or birth outcomes of U.S. women with intellectual and developmental…”
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Antibiotic resistance in acne: changes, consequences and concerns by Karadag, A.S., Aslan Kayıran, M., Wu, C.‐Y., Chen, W., Parish, L.C.

“…Antibiotic resistance in acne was first observed in the 1970s and has been a major concern in dermatology since the 1980s. The resistance rates and types of…”
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A combined cell and gene therapy approach for homotopic reconstruction of midbrain dopamine pathways using human pluripotent stem cells by Moriarty, Niamh, Gantner, Carlos W., Hunt, Cameron P.J., Ermine, Charlotte M., Frausin, Stefano, Viventi, Serena, Ovchinnikov, Dmitry A., Kirik, Deniz, Parish, Clare L., Thompson, Lachlan H.

“…Midbrain dopamine (mDA) neurons can be replaced in patients with Parkinson’s disease (PD) in order to provide long-term improvement in motor functions. The…”
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Pioneers in Dermatology and Venereology: an interview with Prof. Lawrence C. Parish by Parish, L.C.

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The application of human pluripotent stem cells to model the neuronal and glial components of neurodevelopmental disorders by Lee, K. M., Hawi, Z. H., Parkington, H. C., Parish, C. L., Kumar, P. V., Polo, J. M., Bellgrove, M. A., Tong, J.

“…Cellular models of neurodevelopmental disorders provide a valuable experimental system to uncover disease mechanisms and novel therapeutic strategies. The…”
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STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle by Morgan, Ethan L, Wasson, Christopher W, Hanson, Lucy, Kealy, David, Pentland, Ieisha, McGuire, Victoria, Scarpini, Cinzia, Coleman, Nicholas, Arthur, J Simon C, Parish, Joanna L, Roberts, Sally, Macdonald, Andrew

“…Human papillomaviruses (HPV) activate a number of host factors to control their differentiation-dependent life cycles. The transcription factor signal…”
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Identification of cell barcodes from long-read single-cell RNA-seq with BLAZE by You, Yupei, Prawer, Yair D J, De Paoli-Iseppi, Ricardo, Hunt, Cameron P J, Parish, Clare L, Shim, Heejung, Clark, Michael B

“…Long-read single-cell RNA sequencing (scRNA-seq) enables the quantification of RNA isoforms in individual cells. However, long-read scRNA-seq using the Oxford…”
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The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expression by Ferguson, Jack, Campos-León, Karen, Pentland, Ieisha, Stockton, Joanne D, Günther, Thomas, Beggs, Andrew D, Grundhoff, Adam, Roberts, Sally, Noyvert, Boris, Parish, Joanna L

“…The ubiquitous host protein, CCCTC-binding factor (CTCF), is an essential regulator of cellular transcription and functions to maintain epigenetic boundaries,…”
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Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model by Tønnesen, Jan, Parish, Clare L, Sørensen, Andreas T, Andersson, Angelica, Lundberg, Cecilia, Deisseroth, Karl, Arenas, Ernest, Lindvall, Olle, Kokaia, Merab

“…Intrastriatal grafts of stem cell-derived dopamine (DA) neurons induce behavioral recovery in animal models of Parkinson's disease (PD), but how they…”
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Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke by Somaa, Fahad A., Wang, Ting-Yi, Niclis, Jonathan C., Bruggeman, Kiara F., Kauhausen, Jessica A., Guo, Haoyao, McDougall, Stuart, Williams, Richard J., Nisbet, David R., Thompson, Lachlan H., Parish, Clare L.

“…Stem cell transplants offer significant hope for brain repair following ischemic damage. Pre-clinical work suggests that therapeutic mechanisms may be…”
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Human stem cells harboring a suicide gene improve the safety and standardisation of neural transplants in Parkinsonian rats by de Luzy, Isabelle R., Law, Kevin C. L., Moriarty, Niamh, Hunt, Cameron P. J., Durnall, Jennifer C., Thompson, Lachlan H., Nagy, Andras, Parish, Clare L.

“…Despite advancements in human pluripotent stem cells (hPSCs) differentiation protocols to generate appropriate neuronal progenitors suitable for…”
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Promoting engraftment of transplanted neural stem cells/progenitors using biofunctionalised electrospun scaffolds by Wang, Ting-Yi, Forsythe, John S, Nisbet, David R, Parish, Clare L

“…Abstract With the brain's limited capacity for repair, new and innovative approaches are required to promote regeneration. While neural transplantation for a…”
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From infection to cancer: how DNA tumour viruses alter host cell central carbon and lipid metabolism by Magon, Kamini L, Parish, Joanna L

“…Infections cause 13% of all cancers globally, and DNA tumour viruses account for almost 60% of these cancers. All viruses are obligate intracellular parasites…”
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Extracellular Matrix Biomimetic Hydrogels, Encapsulated with Stromal Cell-Derived Factor 1, Improve the Composition of Foetal Tissue Grafts in a Rodent Model of Parkinson's Disease by Penna, Vanessa, Moriarty, Niamh, Wang, Yi, Law, Kevin C L, Gantner, Carlos W, Williams, Richard J, Nisbet, David R, Parish, Clare L

“…Clinical studies have provided evidence for dopamine (DA) cell replacement therapy in Parkinson's Disease. However, grafts derived from foetal tissue or…”
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