Search Results - "Parikh, Zalak"

Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control by Wible, Daric J., Parikh, Zalak, Cho, Eun Jeong, Chen, Miao-Der, Jeter, Collene R., Mukhopadhyay, Somshuvra, Dalby, Kevin N., Varadarajan, Shankar, Bratton, Shawn B.

“…p38 mitogen-activated protein kinases (MAPKs) participate in autophagic signaling; and previous reports suggest that pyridinyl imidazole p38 MAPK inhibitors,…”
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Differential Regulation of MeCP2 Phosphorylation by Laminin in Oligodendrocytes by Parikh, Zalak S., Tripathi, Ashutosh, Pillai, Prakash P.

“…Oligodendrocytes (OLGs) are the myelinating cells of the central nervous system (CNS), and its proper differentiation is crucial for normal functioning of…”
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pERK1/2 Peripheral Recruitment and Filopodia Protrusion Augment Oligodendrocyte Progenitor Cell Migration: Combined Effects of PDGF-A and Fibronectin by Tripathi, Ashutosh, Parikh, Zalak S., Vora, Parvez, Frost, Emma E., Pillai, Prakash P.

“…Oligodendrocyte progenitor cell (OPC) migration is critical for effective myelination of the central nervous system. Not only during normal myelination but…”
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Synthesis and Biological Evaluation of Novel Multi-target-Directed Benzazepines Against Excitotoxicity by Machhi, Jatin, Prajapati, Navnit, Tripathi, Ashutosh, Parikh, Zalak S., Kanhed, Ashish M., Patel, Kirti, Pillai, Prakash P., Giridhar, Rajani, Yadav, Mange Ram

“…Excitotoxicty, a key pathogenic event is characteristic of the onset and development of neurodegeneration. The glutamatergic neurotransmission mediated through…”
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Neuroprotective Potential of Novel Multi-Targeted Isoalloxazine Derivatives in Rodent Models of Alzheimer’s Disease Through Activation of Canonical Wnt/β-Catenin Signalling Pathway by Machhi, Jatin, Sinha, Anshuman, Patel, Pratik, Kanhed, Ashish M., Upadhyay, Pragnesh, Tripathi, Ashutosh, Parikh, Zalak S., Chruvattil, Ragitha, Pillai, Prakash P., Gupta, Sarita, Patel, Kirti, Giridhar, Rajani, Yadav, Mange Ram

“…Previous reports suggest that Alzheimer’s disease is protected by cholinesterase inhibitors. We synthesized some isoalloxazine derivatives and evaluated them…”
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Discovery of isoalloxazine derivatives as a new class of potential anti-Alzheimer agents and their synthesis by Kanhed, Ashish M., Sinha, Anshuman, Machhi, Jatin, Tripathi, Ashutosh, Parikh, Zalak S., Pillai, Prakash P., Giridhar, Rajani, Yadav, Mange Ram

“…[Display omitted] •Isoalloxazine derivatives as novel class of cholinesterase inhibitors are reported.•Compounds reported showed good activity against both…”
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The Use of Human Amnion/Chorion for the Enhancement of Collagen Synthesis and Acceleration of Wound Healing in a Diabetic Rat Model by Schwartz, John, Koutsoumbelis, Stelios, Parikh, Zalak, Sigal, Ian R., Dines, David M., Dines, Joshua, Grande, Daniel A.

“…Diabetic patients have impaired wound repair due to decreased fibroblast infiltration, growth factor production, and angiogenesis. Decellularized human…”
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Benzylpiperidine-Linked Diarylthiazoles as Potential Anti-Alzheimer’s Agents: Synthesis and Biological Evaluation by Shidore, Mahesh, Machhi, Jatin, Shingala, Kaushik, Murumkar, Prashant, Sharma, Mayank Kumar, Agrawal, Neetesh, Tripathi, Ashutosh, Parikh, Zalak, Pillai, Prakash, Yadav, Mange Ram

“…A novel series of hybrid molecules were designed and synthesized by fusing the pharmacophoric features of cholinesterase inhibitor donepezil and diarylthiazole…”
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Regulation of MECP2 Phosphorylation in CNS Glial Cells by Parikh, Zalak

“…Epigenetic programming is the process through which an environmental stimulus during development alters the gene expression by changing the epigenetic marks…”
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Optimization of Degradation Profile for New Scaffold in Cartilage Repair by Shah, Sarav S., Liang, Haixiang, Pandit, Sandeep, Parikh, Zalak, Schwartz, John A., Goldstein, Todd, Lavelle, Lawrence P., Datta, Arindam, Grande, Daniel A.

“…Objective To establish whether a novel biomaterial scaffold with tunable degradation profile will aid in cartilage repair of chondral defects versus…”
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