Search Results - "Paricio, Beatriz Bellosillo"
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Patients with triple-negative, JAK2V617F- and CALR-mutated essential thrombocythemia share a unique gene expression signature
Published in Blood advances (23-02-2021)“…Approximately 10% to 15% of patients with essential thrombocythemia (ET) lack the common driver mutations, so-called “triple-negative” (TN) disease. We…”
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Clinical utility gene card for: hereditary thrombocythemia
Published in European journal of human genetics : EJHG (01-02-2014)Get full text
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The First-in-class Anti-EGFR Antibody Mixture Sym004 Overcomes Cetuximab Resistance Mediated by EGFR Extracellular Domain Mutations in Colorectal Cancer
Published in Clinical cancer research (01-07-2016)“…Approved anti-EGFR antibodies cetuximab and panitumumab provide significant clinical benefit in patients with metastatic colorectal cancer (MCRC). However,…”
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Abstract PS10-27: A phase II proof-of-concept study of palbociclib (P) rechallenge in patients (pts) with hormone receptor (HR)[+]/HER2[-] metastatic breast cancer (MBC) and clinical benefit to prior P-based treatment (BIOPER)
Published in Cancer research (Chicago, Ill.) (15-02-2021)“…Abstract Background: The addition of a cyclin-dependent kinase 4-6 inhibitor (CDK4/6i) to letrozole or fulvestrant significantly improves progression-free…”
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Abstract 6443: Enhanced detection of ctDNA molecular response for immunotherapy treated non-small cell lung cancer through analyses of cell-free and matched white blood cell DNA
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Introduction: Immune checkpoint inhibitors (ICIs) have greatly improved clinical outcomes for patients with non-small cell lung cancer (NSCLC),…”
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The risk of thrombosis in essential thrombocythemia is associated with the type of CALR mutation: A multicentre collaborative study
Published in European journal of haematology (01-03-2021)“…Objectives In patients with essential thrombocythemia (ET), after the JAK2V617F driver mutation, mutations in CALR are common (classified as type 1, 52‐bp…”
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Impact of genotype on leukaemic transformation in polycythaemia vera and essential thrombocythaemia
Published in British journal of haematology (01-09-2017)“…Summary The influence of driver mutations on leukaemic transformation was analysed in 1747 patients with polycythaemia vera or essential thrombocythaemia. With…”
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BRAF-induced tumorigenesis is IKKα-dependent but NF-κB-independent
Published in Science signaling (21-04-2015)“…KRAS mutations contribute to cell proliferation and survival in numerous cancers, including colorectal cancers (CRC). One pathway through which mutant KRAS…”
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Impact of human papilloma virus in patients with oral and oropharyngeal squamous cell carcinomas
Published in Medicina clinica (01-03-2019)“…Although there is scientific evidence demonstrating causation of human papilloma virus (HPV) on squamous cell carcinoma of head and neck, its percentage of…”
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Masked polycythaemia vera: presenting features, response to treatment and clinical outcomes
Published in European journal of haematology (01-01-2016)“…Masked polycythaemia vera (PV) has been proposed as a new entity with poorer outcome than overt PV. In this study, the initial clinical and laboratory…”
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Anti-tumor activity of the combination of bendamustine with vorinostat in diffuse large B-cell lymphoma cells
Published in Leukemia & lymphoma (03-03-2016)“…Current standard-of-care therapy for diffuse large B-cell lymphoma (DLBCL) results in up to 40% of patients who either relapse or develop refractory disease…”
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Characterization of CD34+ hematopoietic progenitor cells in JAK2V617F and CALR-mutated myeloproliferative neoplasms
Published in Leukemia research (01-09-2016)“…•CALR-mutated ET patients harbored a higher mutant load at progenitor level than JAK2-positive ET.•Hematopoietic stem cells of CALR-mutated ET showed a similar…”
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Molecular characterisation of triple negative essential thrombocythaemia patients by platelet analysis and targeted sequencing
Published in Blood cancer journal (New York) (01-08-2016)“…Essential thrombocythaemia (ET) is a myeloproliferative neoplasm(MPN) characterised by megakaryocyte hyperplasia and thrombo-cytosis. From the genetic…”
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14
Impact of human papilloma virus in patients with oral and oropharyngeal squamous cell carcinomas
Published in Medicina clínica (English ed.) (01-03-2019)“…Although there is scientific evidence demonstrating causation of human papilloma virus (HPV) on squamous cell carcinoma of head and neck, its percentage of…”
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15
Patients with triple-negative, JAK2 V617F- and CALR -mutated essential thrombocythemia share a unique gene expression signature
Published in Blood advances (23-02-2021)“…Abstract Approximately 10% to 15% of patients with essential thrombocythemia (ET) lack the common driver mutations, so-called “triple-negative” (TN) disease…”
Get full text
Journal Article -
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miR-203 and miR-221 regulate SOCS1 and SOCS3 in essential thrombocythemia
Published in Blood cancer journal (New York) (18-03-2016)“…The biological basis of essential thrombocythemia (ET) patients lacking known mutations is still unknown. MicroRNAs (miRNA) regulate hematopoietic…”
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Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance
Published in Oncotarget (20-04-2015)“…Invasive malignant melanoma (MM) is an aggressive tumor with no curative therapy available in advanced stages. Nuclear corepressor (NCoR) is an essential…”
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First Achievements of MPN&MPNr-EuroNet (COST Action BM0902), a New European Network Dedicated to the Diagnosis of Myeloproliferative Neoplasms and Hereditary Erythrocytosis and Thrombocytosis
Published in Blood (18-11-2011)“…Abstract 2809 The MPN&MPNr-EuroNet network, created in November 2009, is supported by the European program COST (CoOperation in Science and Technology). It is…”
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MicroRNAs 142-3p, miR-155 and miR-203 are deregulated in gastric MALT LymphomasCompared to chronic gastritis
Published in Cancer genomics & proteomics (2017)“…BACKGROUND: Over the last years, our knowledge on pathogenesis of gastric MALT lymphoma has greatly improved, but its morphological diagnosis is still hampered…”
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