Search Results - "Parhar, Ishwar"

Hypothalamic kisspeptin and kisspeptin receptors: Species variation in reproduction and reproductive behaviours by Sivalingam, Mageswary, Parhar, Ishwar S.

“…•Evolution of Kiss1-Kiss1R diversity, distribution, and regulation.•Essential functions of hypothalamic kisspeptin in mammals and non-mammals.•Controversies…”
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Anti-neoplastic Potential of Flavonoids and Polysaccharide Phytochemicals in Glioblastoma by Atiq, Ayesha, Parhar, Ishwar

“…Clinically, gliomas are classified into four grades, with grade IV glioblastoma multiforme being the most malignant and deadly, which accounts for 50% of all…”
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FoxO1 signaling as a therapeutic target for type 2 diabetes and obesity by Benchoula, Khaled, Arya, Aditya, Parhar, Ishwar S., Hwa, Wong Eng

“…Glucose production and the consumption of high levels of carbohydrate increase the chance of insulin resistance, especially in cases of obesity. Therefore,…”
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Heterogeneity in GnRH and kisspeptin neurons and their significance in vertebrate reproductive biology by Ogawa, Satoshi, Parhar, Ishwar S.

“…•GnRH and kisspeptin neurons exhibit high levels of heterogeneity.•Several intrinsic and extrinsic factors are likely to be involved in the heterogeneity of…”
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MicroRNAs Regulate Cell Cycle and Cell Death Pathways in Glioblastoma by Sati, Isra Saif Eldin Eisa, Parhar, Ishwar

“…Glioblastoma (GBM), a grade IV brain tumor, is known for its heterogenicity and its resistance to the current treatment regimen. Over the last few decades, a…”
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Functions of habenula in reproduction and socio-reproductive behaviours by Ogawa, Satoshi, Parhar, Ishwar S.

“…•The habenula has recently been recognized as a processing centre for emotional decision-making.•The habenula receives innervations from reproductive brain…”
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Cloning and Expression of kiss2 in the Zebrafish and Medaka by Kitahashi, Takashi, Ogawa, Satoshi, Parhar, Ishwar S

“…Newly discovered kisspeptin (metastin), encoded by the Kiss1/KISS1 gene, is considered as a major gatekeeper of puberty through the regulation of GnRH. In the…”
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Single-Cell Gene Profiling Reveals Social Status-Dependent Modulation of Nuclear Hormone Receptors in GnRH Neurons in a Male Cichlid Fish by Ogawa, Satoshi, Parhar, Ishwar S

“…Gonadotropin-releasing hormone (GnRH) is essential for the initiation and maintenance of reproductive functions in vertebrates. To date, three distinct…”
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CREB nuclear transcription activity as a targeting factor in the treatment of diabetes and diabetes complications by Benchoula, Khaled, Parhar, Ishwar S, Madhavan, Priya, Hwa, Wong Eng

“…[Display omitted] Diabetes mellitus is a metabolic disorder diagnosed by elevated blood glucose levels and a defect in insulin production. Blood glucose, an…”
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The crosstalk of hedgehog, PI3K and Wnt pathways in diabetes by Benchoula, Khaled, Parhar, Ishwar S., Wong, Eng Hwa

“…Hyperglycaemia causes pancreatic β-cells to release insulin that then attaches to a specific expression of receptor isoform and reverses high glucose…”
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Effects of photoperiod and temperature on kisspeptin1 (kiss1) expression in the gonads of Clarias batrachus by Singh, Ankur, Lal, Bechan, Parhar, Ishwar S.

“…Photo-thermal regulation of reproduction in seasonally breeding vertebrates, including teleost fishes, is established. The photo-thermal cues are relayed to…”
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Multiple gonadotropin‐releasing hormone systems in non‐mammalian vertebrates: Ontogeny, anatomy, and physiology by Ogawa, Satoshi, Yamamoto, Naoyuki, Hagio, Hanako, Oka, Yoshitaka, Parhar, Ishwar S.

“…Three paralogous genes for gonadotropin‐releasing hormone (GnRH; gnrh1, gnrh2, and gnrh3) and GnRH receptors exist in non‐mammalian vertebrates. However, there…”
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Social stress-induced serotonin dysfunction activates spexin in male Nile tilapia ( Oreochromis Niloticus ) by Lim, Chor Hong, Soga, Tomoko, Parhar, Ishwar S

“…Social disturbance in interpersonal relationships is the primary source of stress in humans. Spexin (SPX, SPX1a in cichlid), an evolutionarily conserved…”
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Brain Beta-Catenin Signalling During Stress and Depression by Teo, Chuin Hau, Soga, Tomoko, Parhar, Ishwar S.

“…Beta-catenin is a protein with dual functions in the cell, playing a role in both adhesion between cells as well as gene transcription via the canonical Wnt…”
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Fish as a model in social neuroscience: conservation and diversity in the social brain network by Ogawa, Satoshi, Pfaff, Donald W., Parhar, Ishwar S.

“…ABSTRACT Mechanisms for fish social behaviours involve a social brain network (SBN) which is evolutionarily conserved among vertebrates. However, considerable…”
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Role of Habenula in Social and Reproductive Behaviors in Fish: Comparison With Mammals by Ogawa, Satoshi, Parhar, Ishwar S

“…Social behaviors such as mating, parenting, fighting, and avoiding are essential functions as a communication tool in social animals, and are critical for the…”
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Gonadotropin-inhibitory hormone mediates behavioral stress responses by Ubuka, Takayoshi, Parhar, Ishwar S., Tsutsui, Kazuyoshi

“…•Stress stimulates GnIH neurons.•GnIH is the mediator of stress by inhibiting the reproductive neuroendocrine axis.•GnIH increases pain and anxiety.•GnIH…”
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Conserved functions of hypothalamic kisspeptin in vertebrates by Sivalingam, Mageswary, Ogawa, Satoshi, Trudeau, Vance L., Parhar, Ishwar S.

“…•The function of the kisspeptin-Kissr pathway in teleosts remains controversial.•Estrogens and metabolic sensitivities are commonly observed in vertebrate…”
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Habenular kisspeptin modulates fear in the zebrafish by Ogawa, Satoshi, Nathan, Fatima M., Parhar, Ishwar S.

“…Kisspeptin, a neuropeptide encoded by the KISS1/Kiss1, and its cognate G protein-coupled receptor, GPR54 (kisspeptin receptor, Kiss-R), are critical for the…”
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Biological Significance of Kisspeptin-Kiss 1 Receptor Signaling in the Habenula of Teleost Species by Ogawa, Satoshi, Parhar, Ishwar S

“…Kisspeptin is a neuropeptide, encoded by kisspeptin 1 (KISS1)/Kiss1 gene, which primarily acts as the regulator of reproductive functions its receptor,…”
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