Search Results - "Parge, Viraj"
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M281, an anti-FcRn antibody, inhibits IgG transfer in a human ex vivo placental perfusion model
Published in American journal of obstetrics and gynecology (01-05-2019)“…The transfer of pathogenic immunoglobulin G antibodies from mother to fetus is a critical step in the pathophysiology of alloimmune and autoimmune diseases of…”
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32: M281, an anti-FcRn antibody, inhibits IgG transfer in a human ex-vivo placental perfusion model
Published in American journal of obstetrics and gynecology (01-01-2019)Get full text
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Abstract 561: Discovery of a potential best-in-class anti-CD38 therapeutic utilizing Fc multimerization
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…CD38 targeting antibodies are at different phases of clinical development, with daratumumab already approved as monotherapy and in combination with standards…”
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Tolerance to the Diuretic Effects of Cannabinoids and Cross-Tolerance to a κ-Opioid Agonist in THC-Treated Mice
Published in The Journal of pharmacology and experimental therapeutics (01-08-2016)“…Daily treatment with cannabinoids results in tolerance to many, but not all, of their behavioral and physiologic effects. The present studies investigated the…”
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M281: A Therapeutic Anti-FcRn Blocking Antibody for Rapid Clearance of IgG and IgG Autoantibodies in Immune Cytopenias and Other Auto/Allo-Immune Disease
Published in Blood (03-12-2015)“…Introduction IgG antibodies are the primary pathogenic agent in a number of auto- or allo-immune diseases. Efficacious therapies which decrease systemic levels…”
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THC mediated tolerance to the diuretic effects of cannabinoids & kappa opioids in mice
Published 01-01-2014“…Cannabinoids and opioids are two of the oldest known categories of drugs, used for their medicinal and recreational properties since ancient times. Drugs…”
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Dissertation