Search Results - "Parenti, Rosalba"
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Connexins Signatures of the Neurovascular Unit and Their Physio-Pathological Functions
Published in International journal of molecular sciences (23-08-2022)“…Central nervous system (CNS) homeostasis is closely linked to the delicate balance of the microenvironment in which different cellular components of the…”
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Collagen-Hydroxyapatite Scaffolds Induce Human Adipose Derived Stem Cells Osteogenic Differentiation In Vitro
Published in PloS one (16-03-2016)“…Mesenchymal stem cells (MSCs) play a crucial role in regulating normal skeletal homeostasis and, in case of injury, in bone healing and reestablishment of…”
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3
Phytochemical Analysis and Anti-Inflammatory and Anti-Osteoarthritic Bioactive Potential of Verbascum thapsus L. (Scrophulariaceae) Leaf Extract Evaluated in Two In Vitro Models of Inflammation and Osteoarthritis
Published in Molecules (Basel, Switzerland) (05-09-2021)“…Osteoarthritis (OA) is a complex disease, source of pain and disability that affects millions of people worldwide. OA etiology is complex, multifactorial and…”
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4
Intercellular communication and ion channels in neuropathic pain chronicization
Published in Inflammation research (01-09-2020)“…Background Neuropathic pain is caused by primary lesion or dysfunction of either peripheral or central nervous system. Due to its complex pathogenesis, often…”
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Human adipose-derived mesenchymal stem cells seeded into a collagen-hydroxyapatite scaffold promote bone augmentation after implantation in the mouse
Published in Scientific reports (02-08-2017)“…Traumatic injury or surgical excision of diseased bone tissue usually require the reconstruction of large bone defects unable to heal spontaneously, especially…”
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6
Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing
Published in Cell death & disease (16-06-2021)“…Motoneuronal loss is the main feature of amyotrophic lateral sclerosis, although pathogenesis is extremely complex involving both neural and muscle cells. In…”
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The Role of Epigenetics in Neuroinflammatory-Driven Diseases
Published in International journal of molecular sciences (02-12-2022)“…Neurodegenerative disorders are characterized by the progressive loss of central and/or peripheral nervous system neurons. Within this context,…”
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Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype
Published in International journal of molecular sciences (20-12-2022)“…Uveal melanoma (UM), the most common primary intraocular cancer in adults, is among the tumors with poorer prognosis. Recently, the role of the oncometabolite…”
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Melatonin Enhances Neural Differentiation of Adipose-Derived Mesenchymal Stem Cells
Published in International journal of molecular sciences (01-05-2024)“…Adipose-derived mesenchymal stem cells (ASCs) are adult multipotent stem cells, able to differentiate toward neural elements other than cells of mesodermal…”
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10
Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain
Published in International journal of molecular sciences (24-05-2022)“…Chronic neuropathic pain emerges from either central or peripheral lesions inducing spontaneous or amplified responses to non-noxious stimuli. Despite…”
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Effect of Ferulic Acid Loaded in Nanoparticle on Tissue Transglutaminase Expression Levels in Human Glioblastoma Cell Line
Published in International journal of molecular sciences (01-08-2024)“…Glioblastoma (GBM) is one of the most aggressive cancers, characterized by a decrease in antioxidant levels. Evidence has demonstrated that ferulic acid (FA),…”
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MiR-19a Overexpression in FTC-133 Cell Line Induces a More De-Differentiated and Aggressive Phenotype
Published in International journal of molecular sciences (07-12-2018)“…In recent years, microRNAs (miRNAs) have received increasing attention for their important role in tumor initiation and progression. MiRNAs are a class of…”
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13
An Advanced, Silicon-Based Substrate for Sensitive Nucleic Acids Detection
Published in Sensors (Basel, Switzerland) (17-09-2018)“…Surface substrate and chemical functionalization are crucial aspects for the fabrication of the sensitive biosensor based on microarray technology. In this…”
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14
Glioblastoma mesenchymal subtype enhances antioxidant defence to reduce susceptibility to ferroptosis
Published in Scientific reports (05-09-2024)“…Glioblastoma (GBM) represents an aggressive brain tumor, characterized by intra- and inter-tumoral heterogeneity and therapy resistance, leading to…”
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15
Connexins in the Central Nervous System: Physiological Traits and Neuroprotective Targets
Published in Frontiers in physiology (18-12-2017)“…Cell-to-cell interaction and cell-to-extracellular environment communication are emerging as new therapeutic targets in neurodegenerative disorders. Dynamic…”
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Connexin expression decreases during adipogenic differentiation of human adipose-derived mesenchymal stem cells
Published in Molecular biology reports (01-12-2020)“…Adipose-derived stem cells (ASCs) represent a valuable tool for regenerative medicine being able to differentiate toward several cell lines, such as…”
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CXCL12/CXCR4 axis supports mitochondrial trafficking in tumor myeloma microenvironment
Published in Oncogenesis (New York, NY) (21-01-2022)“…Mesenchymal stromal cells (MSCs) within the protective microenvironment of multiple myeloma (MM) promote tumor growth, confer chemoresistance and support…”
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18
Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance
Published in Journal of translational medicine (03-11-2023)“…Abstract Background Follicular thyroid cancer (FTC) is a prevalent form of differentiated thyroid cancer, whereas anaplastic thyroid cancer (ATC) represents a…”
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Evaluation of a Cell-Free Collagen Type I-Based Scaffold for Articular Cartilage Regeneration in an Orthotopic Rat Model
Published in Materials (21-05-2020)“…The management of chondral defects represents a big challenge because of the limited self-healing capacity of cartilage. Many approaches in this field obtained…”
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Bone augmentation after ectopic implantation of a cell-free collagen-hydroxyapatite scaffold in the mouse
Published in Scientific reports (08-11-2016)“…The bone grafting is the classical way to treat large bone defects. Among the available techniques, autologous bone grafting is still the most used but,…”
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