Search Results - "Parenti, Astrid"

Different effects of tryptophan 2,3-dioxygenase inhibition on SK-Mel-28 and HCT-8 cancer cell lines by Paccosi, Sara, Cecchi, Marta, Silvano, Angela, Fabbri, Sergio, Parenti, Astrid

“…Purpose Indoleamine 2,3-dioxygenase-1 (IDO1) and more recently, tryptophan 2,3-dioxygenase (TDO), are tryptophan-catabolizing enzymes with immunoregulatory…”
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Obesity Therapy: How and Why? by Paccosi, Sara, Cresci, Barbara, Pala, Laura, Rotella, Carlo Maria, Parenti, Astrid

“…Obesity represents the second preventable mortality cause worldwide, and is very often associated with type 2 Diabetes Mellitus (T2DM). The first line…”
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Oxidative Stress-Induced Endothelial Dysfunction in Cardiovascular Diseases by Shaito, Abdullah, Aramouni, Karl, Assaf, Roland, Parenti, Astrid, Orekhov, Alexander, Yazbi, Ahmed El, Pintus, Gianfranco, Eid, Ali H

“…Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better understanding of the mechanisms underlying CVD is key for better management or…”
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Neutrophil gelatinase-associated lipocalin (NGAL) levels in twin pregnancy and association with gestational diabetes by Silvano, Angela, Ammar, Oumaima, Strambi, Noemi, Sisti, Giovanni, Parenti, Astrid, Seravalli, Viola, Di Tommaso, Mariarosaria

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Inorganic nanoparticles as potential regulators of immune response in dendritic cells by Fogli, Silvia, Montis, Costanza, Paccosi, Sara, Silvano, Angela, Michelucci, Elena, Berti, Debora, Bosi, Alberto, Parenti, Astrid, Romagnoli, Paolo

“…The spontaneous adsorption of proteins on nanoparticles (NPs) in biological media is exploited to prepare complexes of NPs and proteins from cancer cells'…”
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Establishment and characterization of a new spontaneously immortalized ER−/PR−/HER2+ human breast cancer cell line, DHSF-BR16 by Nobili, Stefania, Mannini, Antonella, Parenti, Astrid, Raggi, Chiara, Lapucci, Andrea, Chiorino, Giovanna, Paccosi, Sara, Di Gennaro, Paola, Vezzosi, Vania, Romagnoli, Paolo, Susini, Tommaso, Coronnello, Marcella

“…Invasive ductal carcinoma (IDC) constitutes the most frequent malignant cancer endangering women’s health. In this study, a new spontaneously immortalized…”
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Dual Inhibitors of P-gp and Carbonic Anhydrase XII (hCA XII) against Tumor Multidrug Resistance with Piperazine Scaffold by Braconi, Laura, Riganti, Chiara, Parenti, Astrid, Cecchi, Marta, Nocentini, Alessio, Bartolucci, Gianluca, Menicatti, Marta, Contino, Marialessandra, Colabufo, Nicola Antonio, Manetti, Dina, Romanelli, Maria Novella, Supuran, Claudiu T, Teodori, Elisabetta

“…A new series of piperazine derivatives were synthesized and studied with the aim of obtaining dual inhibitors of P-glycoprotein (P-gp) and carbonic anhydrase…”
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Potential Role for Dendritic Cells in Endothelial Dysfunction, Diabetes and Cardiovascular Disease by Parenti, Astrid, Pala, Laura, Paccosi, Sara, Rotella, Carlo Maria

“…Endothelial dysfunction (ED) is a pathophysiological mechanism present in patients affected by type 2 diabetes (T2DM) supporting the development of…”
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Minocycline affects human neutrophil respiratory burst and transendothelial migration by Parenti, Astrid, Indorato, Boris, Paccosi, Sara

“…Objective This study aimed at investigating the in vitro activity of minocycline and doxycycline on human polymorphonuclear (h-PMN) cell function. Methods…”
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Exploring Plasma-Level Gut Microbiota Mediators and Pro-Inflammatory Markers in Pregnant Women with Short Cervix and Gestational Diabetes Mellitus by Silvano, Angela, Niccolai, Elena, Baldi, Simone, Seravalli, Viola, Strambi, Noemi, Nannini, Giulia, Pallecchi, Marco, Bartolucci, Gianluca, Parenti, Astrid, Amedei, Amedeo, Di Tommaso, Mariarosaria

“…The composition of the gut microbiota (GM) undergoes significant changes during pregnancy, influenced by metabolic status, energy homeostasis, fat storage, and…”
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Unveiling the Role of Tryptophan 2,3-Dioxygenase in the Angiogenic Process by Cecchi, Marta, Anceschi, Cecilia, Silvano, Angela, Coniglio, Maria Luisa, Chinnici, Aurora, Magnelli, Lucia, Lapucci, Andrea, Laurenzana, Anna, Parenti, Astrid

“…Indoleamine 2,3-dioxygenase (IDO1) and tryptophan-2,3-dioxygenase (TDO) are the two principals enzymes involved in the catabolization of tryptophan (Trp) into…”
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Dexamethasone Induces the Expression and Function of Tryptophan-2-3-Dioxygenase in SK-MEL-28 Melanoma Cells by Cecchi, Marta, Paccosi, Sara, Silvano, Angela, Eid, Ali Hussein, Parenti, Astrid

“…Tryptophan-2,3-dioxygenase (TDO) is one of the key tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. Contrary to expectation,…”
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Targeting z-Crystallin by aspirin restores the sensitivity to cisplatin in resistant A2780 ovarian cancer cells by Lulli, Matteo, Trabocchi, Andrea, Roviello, Giandomenico, Catalano, Martina, Papucci, Laura, Parenti, Astrid, Molli, Alice, Napoli, Cristina, Landini, Ida, Schiavone, Nicola, Lapucci, Andrea

“…Ovarian cancer is the deadliest gynaecologic malignancies worldwide. Platinum based chemotherapy is the mainstay treatment for ovarian cancer; however,…”
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Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase by Cecchi, Marta, Mannini, Antonella, Lapucci, Andrea, Silvano, Angela, Lulli, Matteo, Luceri, Cristina, D’Ambrosio, Mario, Chiarugi, Alberto, Eid, Ali H., Parenti, Astrid

“…In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function…”
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Differential Th17 response induced by the two clades of the pandemic ST258 Klebsiella pneumoniae clonal lineages producing KPC-type carbapenemase by Clemente, Ann Maria, Castronovo, Giuseppe, Antonelli, Alberto, D'Andrea, Marco Maria, Tanturli, Michele, Perissi, Eloisa, Paccosi, Sara, Parenti, Astrid, Cozzolino, Federico, Rossolini, Gian Maria, Torcia, Maria Gabriella

“…The spread of KPC-type carbapenemases is mainly attributed to the global dissemination of Klebsiella pneumoniae (KP) strains belonging to the clonal group (CG)…”
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Treatment of Periodontitis for the Prevention of Endothelial Dysfunction: A Narrative Review by Parenti, Astrid, Paccosi, Sara, Cairo, Francesco, Defraia, Efisio

“…Endothelial dysfunction (ED) is the initial step in the development of atherosclerosis, leading to cardiovascular disease (CVD). It has been suggested that…”
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Differences in Inflammatory Response Induced by Two Representatives of Clades of the Pandemic ST258 Klebsiella pneumoniae Clonal Lineage Producing KPC-Type Carbapenemases by Castronovo, Giuseppe, Clemente, Ann Maria, Antonelli, Alberto, D'Andrea, Marco Maria, Tanturli, Michele, Perissi, Eloisa, Paccosi, Sara, Parenti, Astrid, Cozzolino, Federico, Rossolini, Gian Maria, Torcia, Maria Gabriella

“…ST258-K. pneumoniae (ST258-KP) strains, the most widespread multidrug-resistant hospital-acquired pathogens, belong to at least two clades differing in a 215…”
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Characterization of circulating and monocyte-derived dendritic cells in obese and diabetic patients by Musilli, Claudia, Paccosi, Sara, Pala, Laura, Gerlini, Gianni, Ledda, Fabrizio, Mugelli, Alessandro, Rotella, Carlo Maria, Parenti, Astrid

“…► Study on circulating and monocyte-derived DCs in obese and diabetic patients (T2D). ► Obese and T2D patients had higher number of circulating DC precursors…”
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Stimulatory interactions between human coronary smooth muscle cells and dendritic cells by Paccosi, Sara, Musilli, Claudia, Caporale, Roberto, Gelli, Anna Maria Grazia, Guasti, Daniele, Clemente, Ann Maria, Torcia, Maria Gabriella, Filippelli, Amelia, Romagnoli, Paolo, Parenti, Astrid

“…Despite inflammatory and immune mechanisms participating to atherogenesis and dendritic cells (DCs) driving immune and non-immune tissue injury response, the…”
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Unique Associations between Insulin-Like Growth Factor Binding Protein-1, Insulin-Like Growth Factor-1 and T Cell Immunoglobulin Mucin 3 in Successful Twin Pregnancies Conceived with Donor Oocytes by Sisti, Giovanni, Di Tommaso, Mariarosaria, Paccosi, Sara, Parenti, Astrid, Seravalli, Viola, Cuzzola, Roberta, Witkin, Steven S

“…: To investigate if pregnancies conceived using an oocyte donor necessitate an alteration in immune regulation, we compared concentrations of insulin-like…”
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