Search Results - "Pardo, Fabián"

Extracellular vesicles in obesity and diabetes mellitus by Pardo, Fabián, Villalobos-Labra, Roberto, Sobrevia, Bastián, Toledo, Fernando, Sobrevia, Luis

“…Cell-to-cell communication happens via diverse mechanisms including the synthesis, release and transfer to target cells of extracellular vesicles (EVs). EVs…”
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Endoplasmic reticulum stress and development of insulin resistance in adipose, skeletal, liver, and foetoplacental tissue in diabesity by Villalobos-Labra, Roberto, Subiabre, Mario, Toledo, Fernando, Pardo, Fabián, Sobrevia, Luis

“…Diabesity is an abnormal metabolic condition shown by patients with obesity that develop type 2 diabetes mellitus. Patients with diabesity present with insulin…”
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Using Machine Learning to Predict Complications in Pregnancy: A Systematic Review by Bertini, Ayleen, Salas, Rodrigo, Chabert, Steren, Sobrevia, Luis, Pardo, Fabián

“…Artificial intelligence is widely used in medical field, and machine learning has been increasingly used in health care, prediction, and diagnosis and as a…”
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Mitochondrial dysfunction in the fetoplacental unit in gestational diabetes mellitus by Sobrevia, Luis, Valero, Paola, Grismaldo, Adriana, Villalobos-Labra, Roberto, Pardo, Fabián, Subiabre, Mario, Armstrong, Gael, Toledo, Fernando, Vega, Sofía, Cornejo, Marcelo, Fuentes, Gonzalo, Marín, Reinaldo

“…Gestational diabetes mellitus (GDM) is a disease of pregnancy that is associated with d-glucose intolerance and foeto-placental vascular dysfunction. GMD…”
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Molecular implications of adenosine in obesity by Pardo, Fabián, Villalobos-Labra, Roberto, Chiarello, Delia I, Salsoso, Rocío, Toledo, Fernando, Gutierrez, Jaime, Leiva, Andrea, Sobrevia, Luis

“…Adenosine has broad activities in organisms due to the existence of multiple receptors, the differential adenosine concentrations necessary to activate these…”
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Insulin reverses D-glucose-increased nitric oxide and reactive oxygen species generation in human umbilical vein endothelial cells by González, Marcelo, Rojas, Susana, Avila, Pía, Cabrera, Lissette, Villalobos, Roberto, Palma, Carlos, Aguayo, Claudio, Peña, Eduardo, Gallardo, Victoria, Guzmán-Gutiérrez, Enrique, Sáez, Tamara, Salsoso, Rocío, Sanhueza, Carlos, Pardo, Fabián, Leiva, Andrea, Sobrevia, Luis

“…Vascular tone is controlled by the L-arginine/nitric oxide (NO) pathway, and NO bioavailability is strongly affected by hyperglycaemia-induced oxidative…”
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Insulin/adenosine axis linked signalling by Silva, Luis, Subiabre, Mario, Araos, Joaquín, Sáez, Tamara, Salsoso, Rocío, Pardo, Fabián, Leiva, Andrea, San Martín, Rody, Toledo, Fernando, Sobrevia, Luis

“…Regulation of blood flow depends on systemic and local release of vasoactive molecules such as insulin and adenosine. These molecules cause vasodilation by…”
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Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus by Valero, Paola, Fuentes, Gonzalo, Cornejo, Marcelo, Vega, Sofía, Grismaldo, Adriana, Pardo, Fabián, García-Rivas, Gerardo, Hillebrands, Jan-Luuk, Faas, Marijke M., Casanello, Paola, van der Beek, Eline M., van Goor, Harry, Sobrevia, Luis

“…A balanced communication between the mother, placenta and foetus is crucial to reach a successful pregnancy. Several windows of exposure to environmental…”
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Altered foetoplacental vascular endothelial signalling to insulin in diabesity by Pardo, Fabián, Subiabre, Mario, Fuentes, Gonzalo, Toledo, Fernando, Silva, Luis, Villalobos-Labra, Roberto, Sobrevia, Luis

“…Obesity and type 2 diabetes mellitus (T2DM) are diseases associated with hypertension and metabolic alterations. A significant group of patients present both…”
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Glycaemia dynamics in gestational diabetes mellitus by Valero, Paola, Salas, Rodrigo, Pardo, Fabián, Cornejo, Marcelo, Fuentes, Gonzalo, Vega, Sofía, Grismaldo, Adriana, Hillebrands, Jan-Luuk, van der Beek, Eline M., van Goor, Harry, Sobrevia, Luis

“…Pregnant women may develop gestational diabetes mellitus (GDM), a disease of pregnancy characterised by maternal and fetal hyperglycaemia with hazardous…”
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Gestational diabesity and foetoplacental vascular dysfunction by Cornejo, Marcelo, Fuentes, Gonzalo, Valero, Paola, Vega, Sofía, Grismaldo, Adriana, Toledo, Fernando, Pardo, Fabián, Moore‐Carrasco, Rodrigo, Subiabre, Mario, Casanello, Paola, Faas, Marijke M, Goor, Harry, Sobrevia, Luis

“…Gestational diabetes mellitus (GDM) shows a deficiency in the metabolism of D‐glucose and other nutrients, thereby negatively affecting the foetoplacental…”
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Features and behaviours for weight loss in the Chilean cohort with obesity from the ACTION study by Cuevas, Ada, Pardo, Fabián, Alonso, Rodrigo, Barros, Eric, Rendón, Adriana

“…Summary In Latin America, obesity rates are among the highest in the world. Currently, people with obesity (PWO) receive suboptimal care due to several…”
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Pre-pregnancy maternal obesity associates with endoplasmic reticulum stress in human umbilical vein endothelium by Villalobos-Labra, Roberto, Sáez, Pablo J., Subiabre, Mario, Silva, Luis, Toledo, Fernando, Westermeier, Francisco, Pardo, Fabián, Farías, Marcelo, Sobrevia, Luis

“…Obesity associates with the endoplasmic reticulum (ER) stress-induced endothelial dysfunction. Pregnant women with pre-pregnancy maternal obesity (PGMO) may…”
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Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer by Sanhueza, Carlos, Araos, Joaquín, Naranjo, Luciano, Toledo, Fernando, Beltrán, Ana R, Ramírez, Marco A, Gutiérrez, Jaime, Pardo, Fabián, Leiva, Andrea, Sobrevia, Luis

“…Cancer cells generate protons (H+) that are extruded to the extracellular medium mainly via the Na+/H+ exchanger 1 (NHE1), which regulates intracellular pH…”
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Maternal insulin therapy does not restore foetoplacental endothelial dysfunction in gestational diabetes mellitus by Subiabre, Mario, Silva, Luis, Villalobos-Labra, Roberto, Toledo, Fernando, Paublo, Mario, López, Marcia A., Salsoso, Rocío, Pardo, Fabián, Leiva, Andrea, Sobrevia, Luis

“…Pregnant women diagnosed with gestational diabetes mellitus subjected to diet (GDMd) that do not reach normal glycaemia are passed to insulin therapy (GDMi)…”
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Insulin therapy and fetoplacental vascular function in gestational diabetes mellitus by Sobrevia, Luis, Salsoso, Rocío, Sáez, Tamara, Sanhueza, Carlos, Pardo, Fabián, Leiva, Andrea

“…New Findings What is the topic of this review? This review focuses on the effects of insulin therapy on fetoplacental vasculature in gestational diabetes…”
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Adenosine receptors: Modulators of lipid availability that are controlled by lipid levels by Leiva, Andrea, Guzmán-Gutiérrez, Enrique, Contreras-Duarte, Susana, Fuenzalida, Bárbara, Cantin, Claudette, Carvajal, Lorena, Salsoso, Rocío, Gutiérrez, Jaime, Pardo, Fabián, Sobrevia, Luis

“…Adenosine as well as agonists and antagonists for the four adenosine receptor subtypes (A1R, A2AR, A2BR and A3R) play a role in several key physiological and…”
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Preeclampsia associates with RECK-dependent decrease in human trophoblasts migration and invasion by Gutiérrez, Jaime, Aedo, Alejandro, Mora, Jacob, Maldonado, Jorge, Salsoso, Rocío, Toledo, Fernando, Farías, Marcelo, Pardo, Fabián, Leiva, Andrea, Sobrevia, Luis

“…Preeclampsia is characterized by reduced invasion capacity of trophoblasts involving lower matrix metalloproteinase (MMP) activity. Cell invasion is reduced by…”
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Akt/mTOR Role in Human Foetoplacental Vascular Insulin Resistance in Diseases of Pregnancy by González, Marcelo, Pardo, Fabián, Chiarello, Delia I., Leiva, Andrea, Sobrevia, Luis, Toledo, Fernando, Sáez, Tamara, Fuenzalida, Bárbara, Salsoso, Rocío, Araos, Joaquín, Subiabre, Mario, Silva, Luis, Villalobos-Labra, Roberto, Quezada, Claudia

“…Insulin resistance is characteristic of pregnancies where the mother shows metabolic alterations, such as preeclampsia (PE) and gestational diabetes mellitus…”
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Tetrahydrobiopterin Role in human umbilical vein endothelial dysfunction in maternal supraphysiological hypercholesterolemia by Leiva, Andrea, Fuenzalida, Bárbara, Salsoso, Rocío, Barros, Eric, Toledo, Fernando, Gutiérrez, Jaime, Pardo, Fabián, Sobrevia, Luis

“…Maternal physiological hypercholesterolemia (MPH) allows a proper foetal development; however, maternal supraphysiological hypercholesterolemia (MSPH)…”
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