Search Results - "Parcells, Mark"
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Positive Selection Drives Rapid Evolution of the meq Oncogene of Marek's Disease Virus
Published in PloS one (23-09-2016)“…Marek's disease (MD), caused by Marek's disease virus (MDV), a poultry-borne alphaherpesvirus, is a devastating disease of poultry causing an estimated annual…”
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2
Distinct polymorphisms in a single herpesvirus gene are capable of enhancing virulence and mediating vaccinal resistance
Published in PLoS pathogens (11-12-2020)“…Modified-live herpesvirus vaccines are widely used in humans and animals, but field strains can emerge that have a higher virulence and break vaccinal…”
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3
Zika virus infection of pregnant rats and associated neurological consequences in the offspring
Published in PloS one (20-06-2019)“…Zika virus (ZIKV) is a mosquito-borne flavivirus associated with microcephaly and other neurological disorders in infants born to infected mothers. Despite…”
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4
Induction of the unfolded protein response (UPR) during Marek's disease virus (MDV) infection
Published in Virology (New York, N.Y.) (01-09-2018)“…Marek's disease (MD) is a pathology of chickens associated with paralysis, immune suppression, and the rapid formation of T-cell lymphomas. MD is caused by the…”
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5
Comparison of exosomes purified via ultracentrifugation (UC) and Total Exosome Isolation (TEI) reagent from the serum of Marek’s disease virus (MDV)-vaccinated and tumor-bearing chickens
Published in Journal of virological methods (01-01-2019)“…•Ultracentrifugation or TEI reagent purified particles conformed to exosome size.•TEI reagent yielded superior exosome recovery compared to…”
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6
Two class I genes of the chicken MHC have different functions: BF1 is recognized by NK cells while BF2 is recognized by CTLs
Published in Immunogenetics (New York) (01-09-2018)“…The function of the chicken’s major histocompatibility complex ( MHC or B complex) class I major (BF2) and minor (BF1) glycoproteins is compared for their…”
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Comparison of the Transcriptomes and Proteomes of Serum Exosomes from Marek's Disease Virus-Vaccinated and Protected and Lymphoma-Bearing Chickens
Published in Genes (05-02-2019)“…Marek's disease virus (MDV) is the causative agent of Marek's disease (MD), a complex pathology of chickens characterized by paralysis, immunosuppression, and…”
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8
An Engineered Receptor-Binding Domain Improves the Immunogenicity of Multivalent SARS-CoV-2 Vaccines
Published in mBio (11-05-2021)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein mediates viral entry into cells expressing angiotensin-converting enzyme 2…”
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9
Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek's Disease Virus on Transactivation Activity and Virulence
Published in Viruses (14-02-2022)“…Marek's disease virus (MDV) causes malignant lymphoma in chickens (Marek's disease, MD). Although MD is currently controlled by vaccination, MDV strains have…”
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Transcriptional Analyses of Innate and Acquired Immune Patterning Elicited by Marek's Disease Virus Vaccine Strains: Turkey Herpesvirus (HVT), Marek's Disease Virus 2 (strain SB1), and Bivalent Vaccines (HVT/SB1 and HVT-LT/SB1)
Published in Avian diseases (01-12-2019)“…Marek's disease (MD) is a complex pathology of chickens caused by MD virus (MDV) 1 and is observed as paralysis, immune suppression, neurologic signs, and the…”
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11
An investigation into the immune response of cultured neural rat cells following Zika virus infection
Published in Journal of neuroimmunology (15-07-2019)“…The most notable effect of prenatal Zika virus (ZIKV) infection is severe microcephaly. ZIKV has a selective tropism for neural progenitor cells; however, it…”
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12
A Special Issue on Marek's Disease Virus-The Editors' View
Published in Microorganisms (Basel) (01-03-2023)“…Marek's disease virus (MDV), an Alphaherpesvirus belonging to the genus Mardivirus, causes T cell lymphomas in chickens and remains one of the greatest threats…”
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13
A Rat Model of Prenatal Zika Virus Infection and Associated Long-Term Outcomes
Published in Viruses (18-11-2021)“…Zika virus (ZIKV) is a mosquito-borne flavivirus that became widely recognized due to the epidemic in Brazil in 2015. Since then, there has been nearly a…”
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14
Evaluation and validation of reference gene stability during Marek’s disease virus (MDV) infection
Published in Journal of virological methods (01-10-2016)“…•We examined the stability of (5) common housekeeping genes during Marek’s disease virus (MDV) infection: beta actin (BACT), 18S RNA, 28S RNA, GAPDH, and…”
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15
An Examination of the Long-Term Neurodevelopmental Impact of Prenatal Zika Virus Infection in a Rat Model Using a High Resolution, Longitudinal MRI Approach
Published in Viruses (11-06-2021)“…Since Zika virus (ZIKV) first emerged as a public health concern in 2015, our ability to identify and track the long-term neurological sequelae of prenatal…”
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Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses
Published in Cell reports. Medicine (16-05-2023)“…RNA viruses continue to remain a threat for potential pandemics due to their rapid evolution. Potentiating host antiviral pathways to prevent or limit viral…”
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Correction to: Two class I genes of the chicken MHC have different functions: BF1 is recognized by NK cells while BF2 is recognized by CTLs
Published in Immunogenetics (New York) (01-11-2018)“…The Figure 3 in the original version of this article was incorrectly published. In this article the top panel of Figure 3 that describes the amino acid…”
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18
Sequence Conservation and Differential Expression of Marek's Disease Virus MicroRNAs
Published in Journal of Virology (15-12-2008)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Common Live-Attenuated Avian Herpesvirus Vaccine Expresses a Very Potent Oncogene
Published in mSphere (09-10-2019)“…Vaccines play a crucial role in the protection of animals and humans from deadly pathogens. The first vaccine that also protected against cancer was developed…”
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20
A comparison of exosome purification methods using serum of Marek's disease virus (MDV)-vaccinated and -tumor-bearing chickens
Published in Heliyon (01-12-2020)“…Marek's disease (MD) is an alphaherpesvirus (Marek's disease virus, MDV)-induced pathology of chickens associated with paralysis, immunosuppression,…”
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