Search Results - "Paratcha, G"

Participation of hippocampal metabotropic glutamate receptors, protein kinase A and mitogen-activated protein kinases in memory retrieval by Szapiro, G, Izquierdo, L.A, Alonso, M, Barros, D, Paratcha, G, Ardenghi, P, Pereira, P, Medina, J.H, Izquierdo, I

“…The ability to recall past events is a major determinant of survival strategies in all species and is of paramount importance in determining our uniqueness as…”
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GDNF and GFRα: a versatile molecular complex for developing neurons by Paratcha, Gustavo, Ledda, Fernanda

“…The GDNF family ligands (GFLs) signal through the canonical signaling receptor Ret and a glycosyl-phosphatidylinositol-anchored co-receptor, GFRα. In recent…”
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Neurotrophin-4 mediated TrkB activation reinforces morphine-induced analgesia by Ernfors, Patrik, Lucas, Guilherme, Hendolin, Panu, Harkany, Tibor, Agerman, Karin, Paratcha, Gustavo, Holmgren, Carl, Zilberter, Yuri, Sairanen, Mikko, Minichiello, Liliana, Castren, Eero

“…Morphine is a powerful analgesic for severe pain, and this effect is thought to be mediated by inhibitory G-protein coupled receptors (GPCRs). Here we show…”
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RET-independent signaling by GDNF ligands and GFRα receptors by Ibáñez, Carlos F., Paratcha, Gustavo, Ledda, Fernanda

“…The discovery in the late 1990s of the partnership between the RET receptor tyrosine kinase and the GFRα family of GPI-anchored co-receptors as mediators of…”
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The Molecular Basis of the Self/Non-self Selectivity of a Coelenterate Toxin by Meinardi, E., Florinchristensen, M., Paratcha, G., Azcurra, J.M., Florinchristensen, J.

“…Coelenterates produce potent hemolysins inhibited by sphingomyelin (SM) Remarkably, instead of this lipid, their membrane contain a phosphono analogue of it…”
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The Neural Cell Adhesion Molecule NCAM Is an Alternative Signaling Receptor for GDNF Family Ligands by Paratcha, Gustavo, Ledda, Fernanda, Ibáñez, Carlos F.

“…Intercellular communication involves either direct cell-cell contact or release and uptake of diffusible signals, two strategies mediated by distinct and…”
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Pea3 Transcription Factors, Etv4 and Etv5, Are Required for Proper Hippocampal Dendrite Development and Plasticity by Fontanet, Paula Aldana, Ríos, Antonella Soledad, Alsina, Fernando Cruz, Paratcha, Gustavo, Ledda, Fernanda

“…Abstract The proper formation and morphogenesis of dendrites is essential to the establishment of neuronal connectivity. We report that 2 members of the Pea3…”
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High Plasticity of New Granule Cells in the Aging Hippocampus by Trinchero, Mariela F., Buttner, Karina A., Sulkes Cuevas, Jessica N., Temprana, Silvio G., Fontanet, Paula A., Monzón-Salinas, M. Cristina, Ledda, Fernanda, Paratcha, Gustavo, Schinder, Alejandro F.

“…During aging, the brain undergoes changes that impair cognitive capacity and circuit plasticity, including a marked decrease in production of adult-born…”
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Pea3 transcription factor family members Etv4 and Etv5 mediate retrograde signaling and axonal growth of DRG sensory neurons in response to NGF by Fontanet, Paula, Irala, Dolores, Alsina, Fernando C, Paratcha, Gustavo, Ledda, Fernanda

“…Nerve growth factor (NGF) is a target-derived neurotrophic growth factor that controls many aspects of sensory and sympathetic neuronal development. The…”
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Tetraspanin1 promotes NGF signaling by controlling TrkA receptor proteostasis by Ferrero Restelli, Facundo, Fontanet, Paula Aldana, De Vincenti, Ana Paula, Falzone, Tomás Luis, Ledda, Fernanda, Paratcha, Gustavo

“…The molecular mechanisms that control the biosynthetic trafficking, surface delivery, and degradation of TrkA receptor are essential for proper nerve growth…”
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New insights into the control of neurotrophic growth factor receptor signaling: Implications for nervous system development and repair by Alsina, Fernando C., Ledda, Fernanda, Paratcha, Gustavo

“…Neurotrophic growth factors control neuronal development by activating specific receptor tyrosine kinase positive signaling pathways, such as Ras‐MAPK and…”
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Co-alteration of dopamine D2 receptor and muscarinic acetylcholine receptor binding in rat striatum after circling training by Ibarra, G R, Paratcha, G C, Wolansky, M J, Azcurra, J M

“…CIRCLING training (CT) decreases muscarinic acetyl-choline receptor (mAchR) binding in rat striatum. As cholinergic and dopaminergic systems interact strongly…”
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GDNF and GFRα1 promote formation of neuronal synapses by ligand-induced cell adhesion by Ledda, Fernanda, Ibáñez, Carlos F, Paratcha, Gustavo, Sandoval-Guzmán, Tatiana

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Lrig1 Is an Endogenous Inhibitor of Ret Receptor Tyrosine Kinase Activation, Downstream Signaling, and Biological Responses to GDNF by Ledda, Fernanda, Bieraugel, Oliver, Fard, Shahrzad Shirazi, Vilar, Marcal, Paratcha, Gustavo

“…Glial cell line-derived neurotrophic factor (GDNF)/Ret signaling has potent trophic effects on ventral midbrain dopaminergic, motor, sensory, and sympathetic…”
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Decreased phosphorylation of GAP-43/B-50 in striatal synaptic plasma membranes after circling motor activity by PARATCHA, G. C, IBARRA, G. R, CABRERA, R, AZCURRA, J. M

“…The effects of spontaneous circling motor activity on the in vitro phosphorylation of the protein kinase C substrate GAP-43/B-50 was studied on striatal…”
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Endocannabinoids Regulate Interneuron Migration and Morphogenesis by Transactivating the TrkB Receptor by Paul Berghuis, Marton B. Dobszay, Xinyu Wang, Sabrina Spano, Fernanda Ledda, Kyle M. Sousa, Gunnar Schulte, Ernfors, Patrik, Mackie, Ken, Gustavo Paratcha, Yasmin L. Hurd, Tibor Harkany

“…In utero exposure to$\Delta^9-tetrahydrocannabinol$($\Delta^9-THC$, the active component from marijuana, induces cognitive deficits enduring into adulthood…”
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Permanent alteration of muscarinic acetylcholine receptor binding in rat striatum after circling training during development by Ibarra, Gustavo R., Rodriguez, Jorge A., Paratcha, Gustavo Ch, Azcurra, Julio M.

“…We evaluated the effect of circling training (CT) in the expression of muscarinic acetylcholine receptor (mAchR) in developing rat striatum. For this, male and…”
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Released GFR alpha 1 Potentiates Downstream Signaling, Neuronal Survival, and Differentiation via a Novel Mechanism of Recruitment of c-Ret to Lipid Rafts by Paratcha, G, Ledda, F, Baars, L, Coulpier, M, Besset, V, Anders, J, Scott, R, Ibanez, C F

“…Although both c-Ret and GFR alpha 1 are required for responsiveness to GDNF, GFR alpha 1 is widely expressed in the absence of c-Ret, suggesting alternative…”
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LRIG1 negatively regulates RET mutants and is downregulated in thyroid cancer by Lindquist, David, Alsina, Fernando C, Herdenberg, Carl, Larsson, Catharina, Höppener, Jo, Wang, Na, Paratcha, Gustavo, Tarján, Miklós, Tot, Tibor, Henriksson, Roger, Hedman, Håkan

“…Papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC) are characterized by genomic rearrangements and point mutations in the proto-oncogene…”
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GDNF is a chemoattractant factor for neuronal precursor cells in the rostral migratory stream by Paratcha, Gustavo, Ibáñez, Carlos F., Ledda, Fernanda

“…Olfactory bulb (OB) interneurons are generated from neuroblast cells derived from the anterior subventricular zone (SVZa) of the forebrain. The mechanisms…”
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