Search Results - "Parassol, Nadège"
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"Off-label" use of hydroxychloroquine, azithromycin, lopinavir-ritonavir and chloroquine in COVID-19: A survey of cardiac adverse drug reactions by the French Network of Pharmacovigilance Centers
Published in Therapie (01-07-2020)“…COVID-19 is an unprecedented challenge for physicians and scientists. Several publicized drugs are being used with not much evidence of their efficacy such as…”
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Remdesivir and Acute Renal Failure: A Potential Safety Signal From Disproportionality Analysis of the WHO Safety Database
Published in Clinical pharmacology and therapeutics (01-04-2021)“…Remdesivir is approved for emergency use by the US Food and Drug Administration (FDA) and authorized conditionally by the European Medicines Agency (EMA) for…”
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Immune checkpoint inhibitors-induced nephropathy: a French national survey
Published in Cancer Immunology, Immunotherapy (01-11-2021)“…Immune checkpoint inhibitors (ICIs), aiming to foster cancer-targeted immune response, proved to be effective in several advanced malignancies at the price of…”
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Therapeutic Drug Monitoring of Direct Oral Anticoagulants May Increase Their Benefit-Risk Ratio
Published in Journal of cardiovascular pharmacology (01-10-2020)“…The attractiveness of direct oral anticoagulants (DOACs) over vitamin K antagonists, in addition to a better benefit-risk ratio, stems from the fact that no…”
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Signalling crosstalk at the leading edge controls tissue closure dynamics in the Drosophila embryo
Published in PLoS genetics (23-02-2017)“…Tissue morphogenesis relies on proper differentiation of morphogenetic domains, adopting specific cell behaviours. Yet, how signalling pathways interact to…”
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Case Report: Successful Treatment of Steroid-Refractory Immune Checkpoint Inhibitor-Related Pure Red Cell Aplasia With Cyclosporin
Published in Frontiers in oncology (28-08-2020)“…Anemia associated with Immune checkpoint inhibitor (ICI) is usually hemolytic and regenerative. Cases of non-regenerative pure red cell aplasia are rare, and…”
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Risk factors associated with immune checkpoint inhibitor–induced acute kidney injury compared with other immune-related adverse events: a case–control study
Published in Clinical kidney journal (01-10-2022)“…Background Immune checkpoint inhibitors (ICIs) foster anti-cancer immune responses. Their efficacy comes at the cost of immune-related adverse events (IRAEs)…”
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Case Report: Severe Hypercalcemia Following Vitamin D Intoxication in an Infant, the Underestimated Danger of Dietary Supplements
Published in Frontiers in pediatrics (01-02-2022)“…Vitamin D supplementation is routinely introduced in infants, according to medical guidelines. However, vitamin D overdose can result in life-threatening…”
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Lactobacillus casei DN-114 001 inhibits the increase in paracellular permeability of enteropathogenic Escherichia coli-infected T84 cells
Published in Research in microbiology (01-03-2005)“…Probiotics are living microorganisms which, when ingested in adequate amounts, exert health benefits toward the host. For instance, probiotics might act…”
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In vivo characterization of dynein-driven nanovectors using Drosophila oocytes
Published in PloS one (12-12-2013)“…Molecular motors transport various cargoes including vesicles, proteins and mRNAs, to distinct intracellular compartments. A significant challenge in the field…”
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Spontaneous reporting of adverse drug reactions as an outlet for patient dismay? The case of Levothyrox® change of excipients
Published in Fundamental & clinical pharmacology (01-06-2022)“…Following minor changes of excipients of Levothyrox®, the French Pharmacovigilance Database was overwhelmed by patients' spontaneous reports of adverse drug…”
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Spontaneous adverse event notifications by patients subsequent to the marketing of a new formulation of Levothyrox® amidst a drug media crisis: atypical profile as compared with other drugs
Published in Fundamental & clinical pharmacology (01-08-2019)“…Since patients may report spontaneously adverse events associated with their medications, such notifications are constantly on the rise. In 2017, an unexpected…”
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A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart
Published in Basic research in cardiology (01-05-2011)“…Elevated levels of cardiac mitochondrial uncoupling protein 3 (UCP3) and decreased cardiac efficiency (hydraulic power/oxygen consumption) with abnormal…”
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In vivo characterization of dynein-driven nanovectors using Drosophila oocytes
Published in PloS one (2013)“…Molecular motors transport various cargoes including vesicles, proteins and mRNAs, to distinct intracellular compartments. A significant challenge in the field…”
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Major bleeding events in octagenarians associated with drug interactions between dabigatran and P-gp inhibitors
Published in Journal of geriatric cardiology : JGC (01-11-2019)“…The direct oral anticoagulant dabigatran does not require any routine therapeutic drug monitoring. Yet, concerns about possible drug interactions susceptible…”
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Abstract 14321: Dabigatran-Associated Bleedings May Result From Pharmacokinetic Interactions With Mild P-gp Inhibitors in Very Elderly Patients
Published in Circulation (New York, N.Y.) (19-11-2019)“…IntroductionAFib shall concern more than half of the very elderly population by 2050. The benefit risk ratio of anticoagulants must thereforebe optimized in…”
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Incidence of adverse events in antipsychotic-naïve children and adolescents treated with antipsychotic drugs: Results of a multicenter naturalistic study (ETAPE)
Published in European neuropsychopharmacology (01-12-2019)“…•The off-label prescription of antipsychotics is on the rise. There is a significant lack of data on drug safety and adverse events in the short as well as in…”
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