Search Results - "Paramonov, Valeriy"

PIM-induced phosphorylation of Notch3 promotes breast cancer tumorigenicity in a CSL-independent fashion by Landor, Sebastian K.J., Santio, Niina M., Eccleshall, William B., Paramonov, Valeriy M., Gagliani, Ellen K., Hall, Daniel, Jin, Shao-Bo, Dahlström, Käthe M., Salminen, Tiina A., Rivero-Müller, Adolfo, Lendahl, Urban, Kovall, Rhett A., Koskinen, Päivi J., Sahlgren, Cecilia

“…Dysregulation of the developmentally important Notch signaling pathway is implicated in several types of cancer, including breast cancer. However, the specific…”
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Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway by Misiorek, Julia O, Lähdeniemi, Iris A K, Nyström, Joel H, Paramonov, Valeriy M, Gullmets, Josef A, Saarento, Helena, Rivero-Müller, Adolfo, Husøy, Trine, Taimen, Pekka, Toivola, Diana M

“…Keratins (K) are intermediate filament proteins important in protection from cellular stress. K8, K18 and K19 are the main components of keratin filaments in…”
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Genetically-encoded tools for cAMP probing and modulation in living systems by Paramonov, Valeriy M, Mamaeva, Veronika, Sahlgren, Cecilia, Rivero-Müller, Adolfo

“…Intracellular 3'-5'-cyclic adenosine monophosphate (cAMP) is one of the principal second messengers downstream of a manifold of signal transduction pathways,…”
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iGISTA Kinetic Bioassay for Pertussis Toxin Based on Its Effect on Inhibitory GPCR Signaling by Paramonov, Valeriy M, Sahlgren, Cecilia, Rivero-Müller, Adolfo, Pulliainen, Arto T

“…Detection of pertussis toxin (PTX) activity is instrumental for the development and manufacturing of pertussis vaccines. These quality and safety measures…”
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In vitro Targetability Validation of Peptide-Functionalized Mesoporous Silica Nanoparticles in the Presence of Serum Proteins by Paramonov, Valeriy M., Gerstenberg, Melanie, Sahlgren, Cecilia, Lindén, Mika, Rivero-Müller, Adolfo

“…Demonstration of receptor-mediated targeting of nanoparticles to specific organs and/or cell types is an integral aim in many bionanomedicine development…”
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Targeting Somatostatin Receptors By Functionalized Mesoporous Silica Nanoparticles - Are We Striking Home? by Paramonov, Valeriy M, Desai, Diti, Kettiger, Helene, Mamaeva, Veronika, Rosenholm, Jessica M, Sahlgren, Cecilia, Rivero-Müller, Adolfo

“…The concept of delivering nanoformulations to desired tissues by means of targeting membrane receptors of high local abundance by ligands anchored to the…”
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Germline-specific RNA helicase DDX4 forms cytoplasmic granules in cancer cells and promotes tumor growth by Olotu, Opeyemi, Koskenniemi, Anna-Riina, Ma, Lin, Paramonov, Valeriy, Laasanen, Sini, Louramo, Elina, Bourgery, Matthieu, Lehtiniemi, Tiina, Laasanen, Samuli, Rivero-Müller, Adolfo, Löyttyniemi, Eliisa, Sahlgren, Cecilia, Westermarck, Jukka, Ventelä, Sami, Visakorpi, Tapio, Poutanen, Matti, Vainio, Paula, Mäkelä, Juho-Antti, Kotaja, Noora

“…Cancer cells undergo major epigenetic alterations and transcriptomic changes, including ectopic expression of tissue- and cell-type-specific genes. Here, we…”
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