Search Results - "Parameswaran, Saravanan"

Temperature effects on alcohol aggregation phenomena and phase behavior in n-butanol aqueous solution by Parameswaran, Saravanan, Choi, Seungeui, Choi, Jun-Ho

“…[Display omitted] •Molecular and quantitative studies of the UCST behavior in n-butanol/water mixture.•Bifurcating n-butanol aggregation is sensitive to…”
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Discovery of Novel Coumarin Derivatives as Potential Dual Inhibitors against α-Glucosidase and α-Amylase for the Management of Post-Prandial Hyperglycemia via Molecular Modelling Approaches by Patil, Shashank M, Martiz, Reshma Mary, Satish, A M, Shbeer, Abdullah M, Ageel, Mohammed, Al-Ghorbani, Mohammed, Ranganatha, 5th, Lakshmi, Parameswaran, Saravanan, Ramu, Ramith

“…Coumarin derivatives are proven for their therapeutic uses in several human diseases and disorders such as inflammation, neurodegenerative disorders, cancer,…”
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Development of Human Serum Albumin Selective Fluorescent Probe Using Thieno[3,2- b ]pyridine-5( 4H )-one Fluorophore Derivatives by Lee, Suji, Sung, Dan-Bi, Kang, Seungyoon, Parameswaran, Saravanan, Choi, Jun-Ho, Lee, Jong Seok, Han, Min Su

“…The level of human serum albumin (HSA) in biological fluids is a key health indicator and its quantitative determination has great clinical importance. In this…”
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Synthesis of tetra-substituted pyrroles, a potential phosphodiesterase 4B inhibitor, through nickel(II) chloride hexahydrate catalyzed one-pot four-component reaction by Khan, Abu T., Lal, Mohan, Ray Bagdi, Prasanta, Sidick Basha, R., Saravanan, Parameswaran, Patra, Sanjukta

“…A wide variety of tetra-substituted pyrrole derivatives were synthesized through one-pot four-component condensation reaction of aromatic aldehydes,…”
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Transcriptomic insights into skin cancer: A bioinformatics and network biology approach to biomarker identification by Rambabu, Majji, Navanneth Gowda, M., Selvam, Prasanna Kumar, Vasudevan, Karthick, Dasegowda, K.R., Saravanan, Parameswaran, Rohini, Karunakaran

“…Skin cancer is a widespread malignancy that primarily affects light-skinned populations globally, categorized into melanoma and non-melanoma skin cancers…”
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Identification of New Non-BBB Permeable Tryptophan Hydroxylase Inhibitors for Treating Obesity and Fatty Liver Disease by Pagire, Suvarna H, Pagire, Haushabhau S, Park, Kun-Young, Bae, Eun Jung, Kim, Kwang-Eun, Kim, Minhee, Yoon, Jihyeon, Parameswaran, Saravanan, Choi, Jun-Ho, Park, Sungmi, Jeon, Jae-Han, Song, Jin Sook, Bae, Myung Ae, Lee, In-Kyu, Kim, Hail, Suh, Jae Myoung, Ahn, Jin Hee

“…Serotonin (5-hydroxytryptophan) is a hormone that regulates emotions in the central nervous system. However, serotonin in the peripheral system is associated…”
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Unraveling the Rationale Behind Organic Solvent Stability of Lipases by Chakravorty, Debamitra, Parameswaran, Saravanan, Dubey, Vikash Kumar, Patra, Sanjukta

“…Organic solvent-stable lipases have pronounced impact on industrial economy as they are involved in synthesis by esterification, interesterification, and…”
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Discovery of Small Molecules that Target Vascular Endothelial Growth Factor Receptor-2 Signalling Pathway Employing Molecular Modelling Studies by Rampogu, Shailima, Baek, Ayoung, Park, Chanin, Parate, Shraddha, Parameswaran, Saravanan, Park, Yohan, Shaik, Baji, Kim, Ju Hyun, Park, Seok Ju, Lee, Keun Woo

“…Angiogenesis is defined as the formation of new blood vessels and is a key phenomenon manifested in a host of cancers during which tyrosine kinases play a…”
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Identification of hotspot regions of MurB oxidoreductase enzyme using homology modeling, molecular dynamics and molecular docking techniques by Kumar, Vivek, Saravanan, Parameswaran, Arvind, Akanksha, Mohan, C. Gopi

“…Despite the availability of effective chemotherapy and a moderately protective vaccine, new anti-tuberculosis agents are urgently needed to decrease the global…”
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Natural compounds as potential Hsp90 inhibitors for breast cancer-Pharmacophore guided molecular modelling studies by Rampogu, Shailima, Parate, Shraddha, Parameswaran, Saravanan, Park, Chanin, Baek, Ayoung, Son, Minky, Park, Yohan, Park, Seok Ju, Lee, Keun Woo

“…[Display omitted] •Natural compounds are identified as Hsp90 inhibitors.•These compounds show stable interactions with key residues.•Non-quinone containing…”
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Targeting natural compounds against HER2 kinase domain as potential anticancer drugs applying pharmacophore based molecular modelling approaches by Rampogu, Shailima, Son, Minky, Baek, Ayoung, Park, Chanin, Rana, Rabia Mukthar, Zeb, Amir, Parameswaran, Saravanan, Lee, Keun Woo

“…[Display omitted] •Computational methods effectively displayed the inhibitory effects of natural compounds when challenged against breast cancer target.•We…”
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Exploring the Therapeutic Ability of Fenugreek against Type 2 Diabetes and Breast Cancer Employing Molecular Docking and Molecular Dynamics Simulations by Lee, Keun Woo, Rampogu Lemuel, Mary, Parameswaran, Saravanan, Rampogu, Shailima

“…Fenugreek (Trigonella foenum-graecum) is used as a spice throughout the world. It is known for its medicinal properties such as antidiabetic, anticarcinogenic,…”
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Synthesis and biological evaluation of xanthine derivatives with phenacyl group as tryptophan hydroxylase 1 (TPH1) inhibitors for obesity and fatty liver disease by Yoon, Jihyeon, Choi, Won-Il, Parameswaran, Saravanan, Lee, Gwi Bin, Choi, Byeong Wook, Kim, Pyeongkeun, Shin, Dae-Seop, Jeong, Ha Neul, Lee, Seung Mi, Oh, Chang Joo, Jeon, Jae-Han, Lee, In-Kyu, Bae, Myung Ae, Kim, Hail, Ahn, Jin Hee

“…[Display omitted] Tryptophan hydroxylase 1 (TPH1) has emerged as a target for the treatment of metabolic diseases including obesity and fatty liver disease. A…”
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Peripheral Selective Oxadiazolylphenyl Alanine Derivatives as Tryptophan Hydroxylase 1 Inhibitors for Obesity and Fatty Liver Disease by Bae, Eun Jung, Choi, Won Gun, Pagire, Haushabhau S, Pagire, Suvarna H, Parameswaran, Saravanan, Choi, Jun-Ho, Yoon, Jihyeon, Choi, Won-il, Lee, Ji Hun, Song, Jin Sook, Bae, Myung Ae, Kim, Mijin, Jeon, Jae-Han, Lee, In-Kyu, Kim, Hail, Ahn, Jin Hee

“…Tryptophan hydroxylase 1 (TPH1) has been recently suggested as a promising therapeutic target for treating obesity and fatty liver disease. A new series of…”
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Investigation of novel chemical scaffolds targeting prolyl oligopeptidase for neurological therapeutics by Kumar, Raj, Parameswaran, Saravanan, Bavi, Rohit, Baek, Ayoung, Son, Minky, Rampogu, Shailima, Park, Chanin, Lee, Gihwan, Zeb, Amir, Parate, Shraddha, Rana, Rabia Mukhtar, Lee, Keun Woo

“…Prolyl oligopeptidase (POP) is a potential therapeutic target for treatment of several neurological disorders and α-synucleinopathies including Parkinson's…”
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Potential Selective Inhibitors against Rv0183 of Mycobacterium tuberculosis Targeting Host Lipid Metabolism by Saravanan, Parameswaran, Dubey, Vikash Kumar, Patra, Sanjukta

“…Tuberculosis is the second leading infectious killer with 9 million new cases in 2009. Extensive use of pathogen’s lipid metabolism especially in utilizing the…”
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Discovery of novel anti-leishmanial agents targeting LdLip3 lipase by Parameswaran, Saravanan, Saudagar, Prakash, Dubey, Vikash Kumar, Patra, Sanjukta

“…•Rational approach to combat leishmaniasis by targeting its lipid metabolism.•Bioinformatics analysis revealed LdLip3 as promising drug…”
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Science Last Fortnight by Tekam, Manish Kumar, Mathew, Bobby P., Warrier, Rekha, Parameswaran, Saravanan, Datta, Manali, Rekha

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Science Last Fortnight by Siranjothi, K., Balaji, S., Srividhya, K. V., Ramanan, S. Suresh, Datta, Manali, Varghese, Jinsu, Mullasseri, Sileesh, Chandra, G. Sharath, Parameswaran, Saravanan

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Science Last Fortnight by Swamy, H. M. Mahadeva, Deobhanj, Sanghamitra, Srividhya, Shrivastava, Neeta, Varghese, Jinsu, Venkatesu, Pudi, Jain, Aditi, Chandra, G. Sharath, Parameswaran, Saravanan, Srinivasan, R.

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