Search Results - "Paradowska, Agnieszka"
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Effects of Pulsed‐Wave Photobiomodulation Therapy on Human Spermatozoa
Published in Lasers in surgery and medicine (01-04-2022)“…Background and Objectives Previous studies reported that photobiomodulation (PBM) positively affects the mitochondrial respiratory chain in sperm, resulting in…”
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Pharmacogenomics of Anti-TNF Treatment Response Marks a New Era of Tailored Rheumatoid Arthritis Therapy
Published in International journal of molecular sciences (21-02-2022)“…Rheumatoid arthritis (RA) is the most commonly occurring chronic inflammatory arthritis, the exact mechanism of which is not fully understood. Tumor Necrosis…”
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3
Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences
Published in Genome Research (01-08-2009)“…During the haploid phase of mammalian spermatogenesis, nucleosomal chromatin is ultimately repackaged by small, highly basic protamines to generate an…”
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4
Structure, expression pattern and biological activity of molecular complex TREM-2/DAP12
Published in Human immunology (01-06-2013)“…Highlights ► DAP12 seems to be the main adaptor protein associated with TREM-2. ► The TREM-2/DAP12 complex plays an important role in the immune response and…”
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The Role of TNF-α and Anti-TNF-α Agents during Preconception, Pregnancy, and Breastfeeding
Published in International journal of molecular sciences (13-03-2021)“…Tumor necrosis factor-alpha (TNF-α) is a multifunctional Th1 cytokine and one of the most important inflammatory cytokines. In pregnancy, TNF-α influences…”
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6
Evaluation of a clinical pharmacogenetics model to predict methotrexate response in patients with rheumatoid arthritis
Published in The pharmacogenomics journal (01-07-2018)“…Variability of response to treatment hinders successful management of rheumatoid arthritis (RA). Consequently, a clinical pharmacogenetics model for predicting…”
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Current Understanding of an Emerging Role of HLA-DRB1 Gene in Rheumatoid Arthritis-From Research to Clinical Practice
Published in Cells (Basel, Switzerland) (02-05-2020)“…Rheumatoid arthritis (RA) is an autoimmune disease with an unclear pathogenic mechanism. However, it has been proven that the key underlying risk factor is a…”
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miRNAs as Biomarkers and Possible Therapeutic Strategies in Rheumatoid Arthritis
Published in Cells (Basel, Switzerland) (28-01-2022)“…Within the past years, more and more attention has been devoted to the epigenetic dysregulation that provides an additional window for understanding the…”
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9
Th17/Treg-Related Transcriptional Factor Expression and Cytokine Profile in Patients With Rheumatoid Arthritis
Published in Frontiers in immunology (11-12-2020)“…The aim of our study was to determine whether there is a correlation between transcription factors expression and Th17/Treg ratio, cytokine profile in the RA…”
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Genome wide identification of promoter binding sites for H4K12ac in human sperm and its relevance for early embryonic development
Published in Epigenetics (01-09-2012)“…Sperm chromatin reveals two characteristic features in that protamines are the predominant nuclear proteins and remaining histones are highly acetylated…”
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Cytokines and MicroRNAs as Candidate Biomarkers for Systemic Lupus Erythematosus
Published in International journal of molecular sciences (13-10-2015)“…Systemic lupus erythematosus (SLE) is a systemic autoimmune disease, with varied course and symptoms. Its etiology is very complex and not clearly understood…”
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Epigenetic Regulations of AhR in the Aspect of Immunomodulation
Published in International journal of molecular sciences (03-09-2020)“…Environmental factors contribute to autoimmune disease manifestation, and as regarded today, AhR has become an important factor in studies of immunomodulation…”
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miR-10 and Its Negative Correlation with Serum IL-35 Concentration and Positive Correlation with STAT5a Expression in Patients with Rheumatoid Arthritis
Published in International journal of molecular sciences (18-07-2022)“…Circulating free-cell miRNAs are increasingly important as potential non-invasive biomarkers due to the easy accessibility of clinical materials. Moreover,…”
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The Interplay between Transcriptional Factors and MicroRNAs as an Important Factor for Th17/Treg Balance in RA Patients
Published in International journal of molecular sciences (01-10-2020)“…MicroRNAs regulate gene expression of transcriptional factors, which influence Th17/Treg (regulatory T cells) balance, establishing the molecular mechanism of…”
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15
Relationship between VEGF Gene Polymorphisms and Serum VEGF Protein Levels in Patients with Rheumatoid Arthritis
Published in PloS one (11-08-2016)“…Rheumatoid arthritis (RA) is one of the chronic autoimmune diseases, with genetic and environmental predisposition, and synovial angiogenesis is considered to…”
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Serum microRNAs in Systemic Sclerosis, Associations with Digital Vasculopathy and Lung Involvement
Published in International journal of molecular sciences (14-09-2022)“…Background and aims: Systemic sclerosis (SSc) is an autoimmune, rare multisystem chronic disease that is still not well-understood aetiologically and is…”
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Cytokines in the pathogenesis of hemophilic arthropathy
Published in Cytokine & growth factor reviews (01-02-2018)“…[Display omitted] •Hemophilic arthropathy is a frequent complication of joint bleeding episodes in patients with hemophilia and other inherited bleeding…”
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Association study between immune-related miRNAs and mixed connective tissue disease
Published in Arthritis research & therapy (11-01-2021)“…Mixed connective tissue disease (MCTD) is a rare condition that is distinguished by the presence of specific U1-RNP antibodies. Information about its…”
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Mixed Connective Tissue Disease as Different Entity: Global Methylation Aspect
Published in International journal of molecular sciences (01-10-2023)“…Mixed connective tissue disease (MCTD) is a very rare disorder that belongs in the rare and clinically multifactorial groups of diseases. The pathogenesis of…”
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Cell Cultures as a Versatile Tool in the Research and Treatment of Autoimmune Connective Tissue Diseases
Published in Cells (Basel, Switzerland) (01-10-2023)“…Cell cultures are an important part of the research and treatment of autoimmune connective tissue diseases. By culturing the various cell types involved in…”
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