Search Results - "Paradiso, J."

Image-based perceptual analysis of lit environments by Zhao, N, Reinhart, CF, Paradiso, JA

“…Modern lighting systems typically provide a number of control parameters, e.g. colour and intensity, which allows nearly infinite possible configurations in…”
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Preclinical activity of FF-10501-01, a novel inosine-5′-monophosphate dehydrogenase inhibitor, in acute myeloid leukemia by Yang, Hui, Fang, Zhihong, Wei, Yue, Bohannan, Zachary S, Gañán-Gómez, Irene, Pierola, Ana Alfonso, Paradiso, Linda J, Iwamura, Hiroyuki, Garcia-Manero, Guillermo

“…Highlights • FF-10501-01 induces AML leukemic cell death and reduces cell proliferation. • FF-10501-01 shows strong anti-leukemia effect regardless of HMA…”
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Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation by Muggia, F M, Hainsworth, J D, Jeffers, S, Miller, P, Groshen, S, Tan, M, Roman, L, Uziely, B, Muderspach, L, Garcia, A, Burnett, A, Greco, F A, Morrow, C P, Paradiso, L J, Liang, L J

“…A phase II study of liposomal doxorubicin was conducted in patients with ovarian cancer who failed to respond to platinum- and paclitaxel-based regimens…”
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Energy scavenging for mobile and wireless electronics by Paradiso, J.A., Starner, T.

“…Energy harvesting has grown from long-established concepts into devices for powering ubiquitously deployed sensor networks and mobile electronics. Systems can…”
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Energy scavenging with shoe-mounted piezoelectrics by Shenck, N.S., Paradiso, J.A.

“…Decreasing size and power requirements of wearable microelectronics make it possible to replace batteries with systems that capture energy from the user's…”
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Anti-Leukemia Effect of FF-10501-01, a Novel Inosine 5'-Monophosphate Dehydrogenase Inhibitor, in Acute Myeloid Leukemia by Yang, Hui, Bohannan, Zachary S., Fang, Zhihong, Gañán-Gómez, Irene, Wei, Yue, Paradiso, Linda J., Iwamura, Hiroyuki, Garcia-Manero, Guillermo

“…Introduction Inosine 5'- monophosphate dehydrogenase (IMPDH) plays a critical role in nucleotide synthesis by serving as a rate-limiting step for the de novo…”
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Gait Analysis Using a Shoe-Integrated Wireless Sensor System by Bamberg, S., Benbasat, A.Y., Scarborough, D.M., Krebs, D.E., Paradiso, J.A.

“…We describe a wireless wearable system that was developed to provide quantitative gait analysis outside the confines of the traditional motion laboratory. The…”
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Phase 1 Results of FF-10501-01, a Novel Inosine 5'-Monophosphate Dehydrogenase Inhibitor, in Advanced Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS), Including Hypomethylating Agent (HMA) Failures by Garcia-Manero, Guillermo, Yang, Hui, Fang, Zhihong, Kantarjian, Hagop M., DiNardo, Courtney D., Jabbour, Elias J., Pemmaraju, Naveen, Daver, Naval, Delumpa, Ricardo, Loiselle, Christopher, Rivera, Silvia, Anderson, Kristin, Yearby, Brittany, Denton, Susan, Smith, Whitney, Tiefenwerth, Kathleen, Iwamura, Hiroyuki, Gipson, Teletha, Rosner, Michele, Myers, Thomas J., Paradiso, Linda J.

“…Inosine 5'- monophosphate dehydrogenase (IMPDH) is a rate-limiting enzyme that catalyzes de novo synthesis of the guanine nucleotide and is overexpressed in…”
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Anti-tumor and anti-metastasis efficacy of E6201, a MEK1 inhibitor, in preclinical models of triple-negative breast cancer by Lee, Jangsoon, Lim, Bora, Pearson, Troy, Choi, Kuicheon, Fuson, Jon A., Bartholomeusz, Chandra, Paradiso, Linda J., Myers, Thomas, Tripathy, Debu, Ueno, Naoto T.

“…Purpose Triple-negative breast cancer (TNBC) lacks the receptor targets estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2,…”
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Anti-Leukemia Effect of FF-10501-01, a Novel Inosine 5'-Monophosphate Dehydrogenase Inhibitor, in Advanced Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS), Including Hypomethylating Agent (HMA) Failures by Garcia-Manero, Guillermo, Yang, Hui, Fang, Zhihong, DiNardo, Courtney, Jabbour, Elias, Pemmaraju, Naveen, Delumpa, Ricardo, Loiselle, Christopher, Denton, Susan, Smith, Whitney, Iwamura, Hiroyuki, Gipson, Teletha, Rosner, Michele, Madden, Timothy, Myers, Thomas J., Paradiso, Linda J.

“…Inosine 5'- monophosphate dehydrogenase (IMPDH) is a rate-limiting enzyme that catalyzes de novo synthesis of the guanine nucleotide and is overexpressed in…”
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Correction to: Anti-tumor and anti-metastasis efficacy of E6201, a MEK1 inhibitor, in preclinical models of triple-negative breast cancer by Lee, Jangsoon, Lim, Bora, Pearson, Troy, Choi, Kuicheon, Fuson, Jon A., Bartholomeusz, Chandra, Paradiso, Linda J., Myers, Thomas, Tripathy, Debu, Ueno, Naoto T.

“…Unfortunately in the original publication of the article, the author’s funding support has been mentioned incorrectly. The correct funding statement should…”
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E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases by Babiker, Hani M., Byron, Sara A., Hendricks, William P. D., Elmquist, William F., Gampa, Gautham, Vondrak, Jessica, Aldrich, Jessica, Cuyugan, Lori, Adkins, Jonathan, De Luca, Valerie, Tibes, Raoul, Borad, Mitesh J., Marceau, Katie, Myers, Thomas J., Paradiso, Linda J., Liang, Winnie S., Korn, Ronald L., Cridebring, Derek, Von Hoff, Daniel D., Carpten, John D., Craig, David W., Trent, Jeffrey M., Gordon, Michael S.

“…Summary Malignant melanoma (MM) exhibits a high propensity for central nervous system dissemination with ~50% of metastatic MM patients developing brain…”
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Pharmacokinetic and Pharmacodynamic Evaluation of the Glycinamide Ribonucleotide Formyltransferase Inhibitor AG2034 by MCLEOD, H. L, CASSIDY, J, COLLIER, M. A, PARADISO, L. J, ROBERTS, J. D, POWRIE, R. H, PRIEST, D. G, ZORBAS, M. A, SYNOLD, T. W, SHIBATA, S, SPICER, D, BISSETT, D, PITHAVALA, Y. K

“…Glycinamide ribonucleotide formyltransferase (GARFT) is a component of the de novo purine synthesis pathway. AG2034 is a specific inhibitor of GARFT that was…”
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Circulating mononuclear progenitor cells: differential roles for subpopulations in repair of retinal vascular injury by Caballero, Sergio, Hazra, Sugata, Bhatwadekar, Ashay, Li Calzi, Sergio, Paradiso, Linda J, Miller, Leonard P, Chang, Lung-Ji, Kern, Timothy S, Grant, Maria B

“…We examined effect on retinal vascular homing of exogenous CD34(+) and CD14(+) progenitor cells using mouse models of chronic (streptozotocin [STZ]-induced…”
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User Innovation and Hacking by von Hippel, E., Paradiso, J.A.

“…The economy's ongoing shift to user-centered innovation has some attractive qualities. Many users are finding it progressively easier to get precisely what…”
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Parasitic power harvesting in shoes by Kymissis, J., Kendall, C., Paradiso, J., Gershenfeld, N.

“…As the power requirements for microelectronics continue decreasing, environmental energy sources can begin to replace batteries in certain wearable subsystems…”
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Phase I study of AG2034, a targeted GARFT inhibitor, administered once every 3 weeks by ROBERTS, J. D, SHIBATA, S, PARADISO, L. J, CLENDENINN, N. J, SPICER, D. V, MCLEOD, H. L, TOMBES, M. B, KYLE, B, CARROLL, M, SHEEDY, B, COLLIER, M. A, PITHAVALA, Y. K

“…To identify a recommended phase II dose for the second generation glycinamide ribonucleotide transformylase (GARFT) inhibitor, AG2034, administered by…”
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Sub-nanometer displacement sensing for the Nanogate - a tunable nanometer gap by Hongshen Ma, White, J., Paradiso, J., Slocum, A.

“…We have developed a sub-nanometer level displacement sensing system for a MEMS device called the Nanogate. The Nanogate is a tunable nanometer gap between…”
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Musical Applications of Electric Field Sensing by Paradiso, Joseph A., Gershenfeld, Neil

“…Surveys a variety of ways of approaching the design of responsive electronic instruments, in particular focusing on research done with electric field sensing…”
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Survival advantage of combined chemoradiotherapy compared with resection as the initial treatment of patients with regional pancreatic carcinoma : An outcomes trial by SNADY, H, BRUCKNER, H, COOPERMAN, A, PARADISO, J, KIEFER, L

“…Resection of pancreatic carcinoma is resource-intensive with a limited impact on survival. Chemotherapy and/or radiotherapy (RT) have been shown to be…”
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