Search Results - "Paquette, Joseph"
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Stabilization of Columnar Liquid Crystal Phases via Arene-Perfluoroarene Interactions
Published in Organic letters (20-12-2019)“…We report the synthesis of novel polycatenar dibenzopentacenequinones 1 and 2 that are designed to form columnar liquid crystalline phases. The mesomorphic…”
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X‑ray Absorption Near-Edge Structure Spectroscopy of a Stable 6‑Oxoverdazyl Radical and Its Diamagnetic Precursor
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (10-01-2019)“…The electronic structure of 1,3,5-triphenyl-6-oxoverdazyl, a heteroatom-rich stable organic radical, and its diamagnetic 1,3,5-triphenyl-6-oxotetrazane…”
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3
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
Published in Nature biotechnology (01-08-2024)“…Therapeutic small interfering RNA (siRNA) requires sugar and backbone modifications to inhibit nuclease degradation. However, metabolic stabilization by…”
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4
Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+ and Mg2+ in the formulation
Published in Molecular therapy. Nucleic acids (10-12-2024)“…Oligonucleotide therapeutics (ASOs and siRNAs) have been explored for modulation of gene expression in the central nervous system (CNS), with several drugs…”
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Polymers Containing Nickel(II) Complexes of Goedken's Macrocycle: Optimized Synthesis and Electrochemical Characterization
Published in Macromolecular rapid communications. (01-04-2015)“…The synthesis and characterization of a new class of nickel‐containing polymers is described. The optimized copolymerization of alkyne‐bearing nickel(II)…”
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Synthesis of Substituted Dibenz[a,c]anthracenes and an Investigation of Their Liquid-Crystalline Properties
Published in European journal of organic chemistry (01-03-2015)“…We report the synthesis of a series of 2,3,5,6‐tetraalkoxydibenz[a,c]anthracenes bearing substituents (H, OCH3, or CN) in the 11‐ and 12‐positions and an…”
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Probing the structural features that influence the mesomorphic properties of substituted dibenz[a,c]anthracenes
Published in Canadian journal of chemistry (01-04-2017)“…We report the synthesis and mesophase characterization of a series of novel hexaalkoxydibenzanthracenes to probe the effect of side-chain length variation and…”
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Synthesis, characterization, and preceramic properties of π-conjugated polymers based on Ni(II) complexes of goedken's macrocycle
Published in Journal of polymer science. Part A, Polymer chemistry (15-10-2016)“…ABSTRACT Nickel(II) complexes of Goedken's macrocycle bearing alkyne substituents were copolymerized with 2,7‐dibromo‐9,9‐dihexylfluorene,…”
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Synthesis, characterization, and thin‐film properties of 6‐oxoverdazyl polymers prepared by ring‐opening metathesis polymerization
Published in Journal of polymer science. Part A, Polymer chemistry (15-06-2016)“…Redox‐active 6‐oxoverdazyl polymers were synthesized via ring‐opening metathesis polymerization (ROMP) and their solution, bulk, and thin‐film properties…”
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10
mRNA Nuclear Clustering Leads to a Difference in Mutant Huntingtin mRNA and Protein Silencing by siRNAs In Vivo
Published in Nucleic acid therapeutics (01-08-2024)“…Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by CAG repeat expansion in the first exon of the huntingtin gene ( )…”
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Abstract 3244: Improved Fc-mediated effector functions by an anti-CTLA-4 multivalent Fc agent
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Numerous therapeutic monoclonal antibodies (mAbs) rely on antibody-dependent cell cytotoxicity (ADCC), antibody-dependent cell phagocytosis (ADCP) and…”
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12
Design Criteria for Ultrathin Single-Layer Flash Memristors from an Organic Polyradical
Published in Advanced electronic materials (01-11-2016)“…The quest for memory devices with “flash” properties, suitable to retain information without any external power source but capable of satisfying the thinness…”
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Synthesis of Metal-Containing Polymers and Stable Organic Radical-Containing Polymers and Their Use as Advanced Functional Materials
Published 01-01-2016“…The work presented in this thesis details the synthesis and characterization of two different families of multifunctional polymers. The first family involved…”
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Dissertation -
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Synthesis, characterization, and preceramic properties of [pi]-conjugated polymers based on Ni(II) complexes of goedken's macrocycle
Published in Journal of polymer science. Part A, Polymer chemistry (15-10-2016)“…Nickel(II) complexes of Goedken's macrocycle bearing alkyne substituents were copolymerized with 2,7-dibromo-9,9-dihexylfluorene, 2,5-dibromo-3-hexylthiophene,…”
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Synthesis and Investigation of the Liquid Crystalline Properties of Polycyclic Aromatic Hydrocarbons
Published 01-01-2012“…In this thesis, the synthesis and liquid crystalline properties of a series of novel substituted dibenz[a,c]anthracenes is reported. Specifically, a series of…”
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Dissertation -
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Synthesis and Investigation of the Liquid Crystalline Properties of Polycyclic Aromatic Hydrocarbons
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Dissertation -
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A statistical procedure to assess the significance level of barriers to gene flow
Published in Journal of genetics and genomics (01-11-2009)“…Although several methods are available to study the extent of isolation by distance (IBD) among natural populations, comparatively few exist to detect the…”
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An 8-week reactive balance training program in older healthy adults: A preliminary investigation
Published in Journal of sport and health science (01-09-2015)“…Background: This preliminary study examined the effects of an 8-week supervised reactive balance training program on reaction time (RT) and foot speed, static…”
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Applying to clinical and counseling psychology programs: A guide for people with learning disabilities
Published 01-01-1997“…The goal of this dissertation was to produce a resource guide that people with learning disabilities could use in the application process to graduate clinical…”
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Dissertation