Search Results - "Paquet, Agnes C"
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Inflammatory and repair pathways induced in human bronchoalveolar lavage cells with ozone inhalation
Published in PloS one (02-06-2015)“…Inhalation of ambient levels of ozone causes airway inflammation and epithelial injury. To examine the responses of airway cells to ozone-induced oxidative…”
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IL-13 and Epidermal Growth Factor Receptor Have Critical but Distinct Roles in Epithelial Cell Mucin Production
Published in American journal of respiratory cell and molecular biology (01-02-2007)“…Overproduction of mucus is a central feature of asthma. The cytokine, IL-13, epidermal growth factor receptor (EGFR), and transcription factor, FOXA2, have…”
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Severe Preeclampsia-Related Changes in Gene Expression at the Maternal-Fetal Interface Include Sialic Acid-Binding Immunoglobulin-Like Lectin-6 and Pappalysin-2
Published in Endocrinology (Philadelphia) (01-01-2009)“…Preeclampsia (PE), which affects 4–8% of human pregnancies, causes significant maternal and neonatal morbidity and mortality. Within the basal plate, placental…”
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Gene Expression Profiling of the Human Maternal-Fetal Interface Reveals Dramatic Changes between Midgestation and Term
Published in Endocrinology (Philadelphia) (01-03-2007)“…Human placentation entails the remarkable integration of fetal and maternal cells into a single functional unit. In the basal plate region (the maternal-fetal…”
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A Distinctive Alveolar Macrophage Activation State Induced by Cigarette Smoking
Published in American journal of respiratory and critical care medicine (01-12-2005)“…Macrophages are believed to play a central role in emphysema based largely on data from mouse models. However, the relevance of these models to smoking-related…”
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HOXA3 Modulates Injury‐Induced Mobilization and Recruitment of Bone Marrow‐Derived Cells
Published in Stem cells (Dayton, Ohio) (01-07-2009)“…The regulated recruitment and differentiation of multipotent bone marrow‐derived cells (BMDCs) to sites of injury are critical for efficient wound healing…”
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Differences in reversion of resistance mutations to wild-type under structured treatment interruption and related increase in replication capacity
Published in PloS one (31-01-2011)“…The CPCRA 064 study examined the effect of structured treatment interruption (STI) of up to 4 months followed by salvage treatment in patients failing therapy…”
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Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-β1
Published in Cardiovascular research (01-09-2013)“…Animal studies show that transforming growth factor-β1 (TGF-β1) is an important mediator of atrial fibrosis and atrial fibrillation (AF). This study…”
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Quantitative measurement of HER2 expression in breast cancers: comparison with 'real-world' routine HER2 testing in a multicenter Collaborative Biomarker Study and correlation with overall survival
Published in Breast cancer research : BCR (18-03-2015)“…Accurate assessment of HER2 status is critical in determining appropriate therapy for breast cancer patients but the best HER2 testing methodology has yet to…”
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10
Predicting HIV-1 broadly neutralizing antibody epitope networks using neutralization titers and a novel computational method
Published in BMC bioinformatics (19-03-2014)“…Recent efforts in HIV-1 vaccine design have focused on immunogens that evoke potent neutralizing antibody responses to a broad spectrum of viruses circulating…”
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A decade of HIV-1 drug resistance in the United States: trends and characteristics in a large protease/reverse transcriptase and co-receptor tropism database from 2003 to 2012
Published in Antiviral therapy (01-01-2014)“…Drug resistance testing and co-receptor tropism determination are key components of the management of antiretroviral therapy for HIV-1-infected individuals…”
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HIV Type 1 Polymerase Gene Polymorphisms Are Associated With Phenotypic Differences in Replication Capacity and Disease Progression
Published in The Journal of infectious diseases (01-01-2014)“…Background. Determinants of intersubtype differences in human immunodeficiency virus type 1 (HIV-1) clinical disease progression remain unknown. Methods. HIV-1…”
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Genetic Analysis of Congenital Cystic Adenomatoid Malformation Reveals a Novel Pulmonary Gene: Fatty Acid Binding Protein-7 (Brain Type)
Published in Pediatric research (01-07-2008)“…The pathogenesis of congenital cystic adenomatoid malformation (CCAM) is unknown and its natural history is unpredictable. Fatty acid binding protein-7…”
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Analytical Validation of a Highly Quantitative, Sensitive, Accurate, and Reproducible Assay (HERmark^®) for the Measurement of HER2 Total Protein and HER2 Homodimers in FFPE Breast Cancer Tumor Specimens
Published in Pathology Research International (28-06-2010)“…We report here the results of the analytical validation of assays that measure HER2 total protein (H2T) and HER2 homodimer (H2D) expression in Formalin Fixed…”
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Minimal sequence variability of the region of HIV-1 integrase targeted by the Abbott RealTime HIV-1 viral load assay in clinical specimens with reduced susceptibility to raltegravir
Published in Journal of virological methods (01-11-2013)“…The Abbott RealTime (ART) HIV-1 assay targets the integrase region and is designed to tolerate mismatches. Variability in integrase sequences comprising the…”
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Antiretroviral drug susceptibility among drug-naive adults with recent HIV infection in Rakai, Uganda
Published in AIDS (London) (27-04-2009)“…To analyze antiretroviral drug susceptibility in HIV from recently infected adults in Rakai, Uganda, prior to the availability of antiretroviral drug…”
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A case-based reasoning system for genotypic prediction of HIV-1 co-receptor tropism
Published in Journal of bioinformatics and computational biology (01-08-2013)“…Accurate co-receptor tropism (CRT) determination is critical for making treatment decisions in HIV management. We created a genotypic tropism prediction tool…”
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Differential gene expression by integrin β7+ and β7- memory T helper cells
Published in BMC immunology (05-07-2004)“…BACKGROUND: The cell adhesion molecule integrin α4β7 helps direct the migration of blood lymphocytes to the intestine and associated lymphoid tissues. We…”
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Transforming Growth Factor β1 Inhibits Cystic Fibrosis Transmembrane Conductance Regulator-dependent cAMP-stimulated Alveolar Epithelial Fluid Transport via a Phosphatidylinositol 3-Kinase-dependent Mechanism
Published in The Journal of biological chemistry (12-02-2010)“…Exogenous or endogenous β₂-adrenergic receptor agonists enhance alveolar epithelial fluid transport via a cAMP-dependent mechanism that protects the lungs from…”
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Differential gene expression by integrin beta 7 super(+ )and beta 7 super(-)memory T helper cells
Published in BMC immunology (01-01-2004)“…Background: The cell adhesion molecule integrin alpha 4 beta 7 helps direct the migration of blood lymphocytes to the intestine and associated lymphoid…”
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