Search Results - "Papsun, Donna"
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Isotonitazene Quantitation and Metabolite Discovery in Authentic Forensic Casework
Published in Journal of analytical toxicology (31-07-2020)“…The synthetic opioid landscape continues to change as non-fentanyl-related substances appear in forensic toxicology casework. Among the newest synthetic…”
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Elucidating the potential role of microorganisms in postmortem biotransformation: a comparison of clonazolam and its metabolite in postmortem and DUID cases
Published in Journal of analytical toxicology (28-10-2024)“…Clonazolam is a designer triazolobenzodiazepine first synthesized in 1971 and is primarily used for its anxiolytic and sedative effects. It became a drug of…”
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Proliferation of Novel Synthetic Opioids in Postmortem Investigations After Core-Structure Scheduling for Fentanyl-Related Substances
Published in The American journal of forensic medicine and pathology (01-12-2022)“…Abstract New generations of novel synthetic opioids (NSOs) have emerged to fill a void in the illicit drug markets left by the decline in popularity of…”
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Analysis of Fentanyl and 18 Novel Fentanyl Analogs and Metabolites by LC-MS-MS, and report of Fatalities Associated with Methoxyacetylfentanyl and Cyclopropylfentanyl
Published in Journal of analytical toxicology (01-11-2018)“…Methoxyacetylfentanyl and cyclopropylfentanyl are two of the newest illicit opioids that are infiltrating the heroin market. Methoxyacetylfentanyl and…”
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5
Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs
Published in Analytical and bioanalytical chemistry (01-09-2023)“…The emergence of structurally diverse new synthetic opioids (NSOs) has caused the opioid crisis to spiral to new depths. Little information is available about…”
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Increasing prevalence of designer benzodiazepines in impaired driving: A 5-year analysis from 2017 to 2021
Published in Journal of analytical toxicology (01-11-2023)“…Abstract Designer benzodiazepine (DBZD) use has been increasing over the past decade and poses a threat to human health and safety, particularly when involved…”
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Metonitazene in the United States—Forensic toxicology assessment of a potent new synthetic opioid using liquid chromatography mass spectrometry
Published in Drug testing and analysis (01-10-2021)“…Metonitazene is considered a new psychoactive substance (NPS) and emerging potent synthetic opioid, causing increased public health concern beginning in 2020…”
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Bromazolam in Impaired Driving Investigations
Published in Journal of analytical toxicology (15-11-2024)“…The designer benzodiazepine bromazolam is increasingly encountered in forensic casework, including impaired driving investigations. A series of suspected…”
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The Rise and Fall of Isotonitazene and Brorphine: Two Recent Stars in the Synthetic Opioid Firmament
Published in Journal of analytical toxicology (24-02-2022)“…Abstract Synthetic opioids constitute one of the fastest-growing groups of new psychoactive substances (NPS) worldwide. With fentanyl analogues being…”
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10
The Trouble With Kratom: Analytical and Interpretative Issues Involving Mitragynine
Published in Journal of analytical toxicology (10-09-2019)“…Abstract Mitragynine is the primary active alkaloid in the leaves of the tropical tree Mitragyna speciosa, and goes by the popular names “Kratom”, biak-biak…”
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Brorphine—Investigation and quantitation of a new potent synthetic opioid in forensic toxicology casework using liquid chromatography‐mass spectrometry
Published in Journal of forensic sciences (01-03-2021)“…New synthetic opioids continue to appear as novel psychoactive substances (NPS) on illicit drug markets. Isotonitazene emerged in mid‐2019, becoming the most…”
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Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid
Published in Archives of toxicology (01-06-2022)“…Novel synthetic opioids continue to emerge on recreational drug markets worldwide. In response to legislative bans on fentanyl analogues, non-fentanyl…”
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Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2013–2016: A Review
Published in Journal of analytical toxicology (01-09-2017)“…Abstract Novel psychoactive substances (NPS) represent significant analytical and interpretive challenges to forensic and clinical toxicologists. Timely access…”
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Metabolic profile determination of 2F‐viminol – A novel synthetic opioid identified in forensic investigations
Published in Journal of forensic sciences (01-01-2023)“…Novel synthetic opioid (NSO) continue to emerge in the United States in the midst of an opioid crisis. The NSO 2F‐viminol was identified in casework at the…”
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15
The Development and Validation of a Novel Designer Benzodiazepines Panel by LC–MS-MS
Published in Journal of analytical toxicology (14-05-2021)“…Abstract Novel illicit benzodiazepines are among the most active areas of new illicit drug manufacture and use. We describe a method for the detection and…”
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Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238
Published in Archives of toxicology (01-06-2022)“…The recent scheduling actions of fentanyl-related substances in both the United States and China have sparked the emergence and proliferation of other…”
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Eutylone Intoxications—An Emerging Synthetic Stimulant in Forensic Investigations
Published in Journal of analytical toxicology (06-02-2021)“…Abstract Synthetic stimulants are the largest class of novel psychoactive substances identified each year by forensic laboratories internationally. While…”
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Flualprazolam Blood Concentrations in 197 Forensic Investigation Cases
Published in Journal of analytical toxicology (12-03-2021)“…Flualprazolam is a designer benzodiazepine and novel psychoactive substance that is increasing in prevalence and appearing in forensic investigations…”
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Determination of fentanyl contamination on United States paper currency by LC-QQQ-MS
Published in Journal of analytical toxicology (28-03-2024)“…Previous research has evaluated the extent to which cocaine and other drugs were detectable on currency in the USA. The literature was in agreement that the…”
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N-Ethyl Pentylone (Ephylone) Intoxications: Quantitative Confirmation and Metabolite Identification in Authentic Human Biological Specimens
Published in Journal of analytical toxicology (01-09-2018)“…N-ethyl pentylone (ephylone) has been identified as the most recent novel stimulant to emerge into the arena of evolving novel psychoactive substances (NPS)…”
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