Search Results - "Paprotka, Kerstin"
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Intracellular Staphylococcus aureus employs the cysteine protease staphopain A to induce host cell death in epithelial cells
Published in PLoS pathogens (02-09-2021)“…Staphylococcus aureus is a major human pathogen, which can invade and survive in non-professional and professional phagocytes. Uptake by host cells is thought…”
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Infection of human organoids supports an intestinal niche for Chlamydia trachomatis
Published in PLoS pathogens (22-08-2024)“…Several reports suggest that intestinal tissue may be a natural niche for Chlamydia trachomatis infection and a reservoir for persistent infections in the…”
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Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins
Published in Virulence (01-12-2021)“…A large proportion of clinical S. aureus isolates that carry an inactive Agr system are associated with persistent infection that is difficult to treat. Once…”
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Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes
Published in PLoS pathogens (01-09-2016)“…Community-acquired (CA) Staphylococcus aureus cause various diseases even in healthy individuals. Enhanced virulence of CA-strains is partly attributed to…”
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Staphylococcus aureus α-Toxin Induces Acid Sphingomyelinase Release From a Human Endothelial Cell Line
Published in Frontiers in microbiology (29-07-2021)“…Staphylococcus aureus ( S. aureus ) is well known to express a plethora of toxins of which the pore-forming hemolysin A (α-toxin) is the best-studied…”
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The Expandables: Cracking the Staphylococcal Cell Wall for Expansion Microscopy
Published in Frontiers in cellular and infection microbiology (16-03-2021)“…Expansion Microscopy (ExM) is a novel tool improving the resolution of fluorescence microscopy by linking the sample into a hydrogel that gets physically…”
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A Role of Sphingosine in the Intracellular Survival of Neisseria gonorrhoeae
Published in Frontiers in cellular and infection microbiology (12-05-2020)“…Obligate human pathogenic Neisseria gonorrhoeae are the second most frequent bacterial cause of sexually transmitted diseases. These bacteria invade different…”
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Staphylococcal Alpha-Toxin Is Not Sufficient To Mediate Escape from Phagolysosomes in Upper-Airway Epithelial Cells
Published in Infection and Immunity (01-09-2009)“…Intracellular Staphylococcus aureus has been implicated in the establishment of chronic infections. It is therefore imperative to understand by what means S…”
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Potential protective role of apoprotein J (clusterin) in atherogenesis: binding to enzymatically modified low-density lipoprotein reduces fatty acid-mediated cytotoxicity
Published in Thrombosis and haemostasis (01-07-2008)“…Following entrapment in the arterial intima, low-density lipoprotein (LDL) can be modified by hydrolytic enzymes to yield a lipoprotein derivative that binds…”
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AP-1 in Toxoplasma gondii Mediates Biogenesis of the Rhoptry Secretory Organelle from a Post-Golgi Compartment
Published in The Journal of biological chemistry (14-02-2003)“…We have previously demonstrated that Toxoplasma gondii has a tyrosine-based sorting system, which mediates protein targeting to the lysosome-like rhoptry…”
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A novel point mutation promotes growth phase-dependent daptomycin tolerance in Staphylococcus aureus
Published in Antimicrobial agents and chemotherapy (01-09-2015)“…Recalcitrance of genetically susceptible bacteria to antibiotic killing is a hallmark of bacterial drug tolerance. This phenomenon is prevalent in biofilms,…”
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A point mutation in an unusual Sec7 domain is linked to brefeldin A resistance in a Plasmodium falciparum line generated by drug selection
Published in Molecular microbiology (01-09-2001)“…The malaria parasite Plasmodium falciparum has an unusual organization of its secretory compartments. As an approach to a functional identification of…”
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Infection of human organoids supports an intestinal niche for Chlamydia trachomatis
Published in PLoS pathogens (01-08-2024)Get full text
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Cytoplasmic replication of Staphylococcus aureus upon phagosomal escape triggered by phenol‐soluble modulin α
Published in Cellular microbiology (01-04-2014)“…Summary Staphylococcus aureus is a Gram‐positive human pathogen that is readily internalized by professional phagocytes such as macrophages and neutrophils but…”
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Expression of δ-toxin by Staphylococcus aureus mediates escape from phago-endosomes of human epithelial and endothelial cells in the presence of β-toxin
Published in Cellular microbiology (01-02-2011)“…Staphylococcus aureus is able to invade non-professional phagocytes by interaction of staphylococcal adhesins with extracellular proteins of mammalian cells…”
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Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation
Published in Proceedings of the National Academy of Sciences - PNAS (31-05-2016)“…Staphylococcus aureus is a major bacterial pathogen, which causes severe blood and tissue infections that frequently emerge by autoinfection with…”
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Codon-improved fluorescent proteins in investigation of Staphylococcus aureus host pathogen interactions
Published in Journal of microbiological methods (01-10-2010)“…Here we present the use of three fluorescent proteins in Staphylococcus aureus, Cerulean, PA-GFP, and mRFPmars. All molecules have an improved codon adaptation…”
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Cytoplasmic replication of Staphylococcus aureus upon phagosomal escape triggered by phenol-soluble modulin [alpha]
Published in Cellular microbiology (01-04-2014)“…Summary Staphylococcus aureus is a Gram-positive human pathogen that is readily internalized by professional phagocytes such as macrophages and neutrophils but…”
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Possible protective role for C-reactive protein in atherogenesis: Complement activation by modified lipoproteins halts before detrimental terminal sequence
Published in Circulation (New York, N.Y.) (20-04-2004)“…Previous work indicated that enzymatically remodeled LDL (E-LDL) might activate complement in atherosclerotic lesions via a C-reactive protein (CRP)-dependent…”
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