Search Results - "Pappas, T"

Association between human rhinovirus C and severity of acute asthma in children by Bizzintino, J, Lee, W-M, Laing, I A, Vang, F, Pappas, T, Zhang, G, Martin, A C, Khoo, S-K, Cox, D W, Geelhoed, G C, McMinn, P C, Goldblatt, J, Gern, J E, Le Souëf, P N

“…A new and potentially more pathogenic group of human rhinovirus (HRV), group C (HRVC), has recently been discovered. We hypothesised that HRVC would be present…”
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Human disease-causing mutations result in loss of leiomodin 2 through nonsense-mediated mRNA decay by Pappas, Christopher T, Mayfield, Rachel M, Dickerson, Ava E, Mi-Mi, Lei, Gregorio, Carol C

“…The leiomodin (Lmod) family of actin-binding proteins play a critical role in muscle function, highlighted by the fact that mutations in all three family…”
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Nebulin regulates actin filament lengths by a stabilization mechanism by Pappas, Christopher T, Krieg, Paul A, Gregorio, Carol C

“…Efficient muscle contraction requires regulation of actin filament lengths. In one highly cited model, the giant protein nebulin has been proposed to function…”
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Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality by Pappas, Christopher T., Mayfield, Rachel M., Henderson, Christine, Jamilpour, Nima, Cover, Cathleen, Hernandez, Zachary, Hutchinson, Kirk R., Chu, Miensheng, Nam, Ki-Hwan, Valdez, Jose M., Wong, Pak Kin, Granzier, Henk L., Gregorio, Carol C.

“…Leiomodin 2 (Lmod2) is an actin-binding protein that has been implicated in the regulation of striated muscle thin filament assembly; its physiological…”
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In vivo elongation of thin filaments results in heart failure by Mi-Mi, Lei, Farman, Gerrie P, Mayfield, Rachel M, Strom, Joshua, Chu, Miensheng, Pappas, Christopher T, Gregorio, Carol C

“…A novel cardiac-specific transgenic mouse model was generated to identify the physiological consequences of elongated thin filaments during post-natal…”
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Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization by Donlin, Laura T, Andresen, Christian, Just, Steffen, Rudensky, Eugene, Pappas, Christopher T, Kruger, Martina, Jacobs, Erica Y, Unger, Andreas, Zieseniss, Anke, Dobenecker, Marc-Werner, Voelkel, Tobias, Chait, Brian T, Gregorio, Carol C, Rottbauer, Wolfgang, Tarakhovsky, Alexander, Linke, Wolfgang A

“…Protein lysine methylation is one of the most widespread post-translational modifications in the nuclei of eukaryotic cells. Methylated lysines on histones and…”
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Deleting titin’s I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function by Granzier, Henk L., Hutchinson, Kirk R., Tonino, Paola, Methawasin, Mei, Li, Frank W., Slater, Rebecca E., Bull, Mathew M., Saripalli, Chandra, Pappas, Christopher T., Gregorio, Carol C., Smith, John E.

“…Significance Mutations in titin are a major cause of heart failure, yet the functions of large parts of titin are not understood. Here we studied titin’s…”
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Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats by Kihara, N, de la Fuente, S G, Fujino, K, Takahashi, T, Pappas, T N, Mantyh, C R

“…Background and aims: The role of sensory neurones in colitis was studied by chemical denervation of primary sensory neurones as well as antagonism of the…”
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Content-aware resource allocation and packet scheduling for video transmission over wireless networks by Pahalawatta, P., Berry, R., Pappas, T., Katsaggelos, A.

“…A cross-layer packet scheduling scheme that streams pre-encoded video over wireless downlink packet access networks to multiple users is presented. The scheme…”
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Effects of Static and Dynamic Stretching on Sprint and Jump Performance in Boys and Girls by Paradisis, Giorgos P, Pappas, Panagiotis T, Theodorou, Apostolos S, Zacharogiannis, Elias G, Skordilis, Emmanouil K, Smirniotou, Athanasia S

“…ABSTRACTParadisis, GP, Pappas, PT, Theodorou, AS, Zacharogiannis, EG, Skordilis, EK, and Smirniotou, AS. Effects of static and dynamic stretching on sprint and…”
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Leiomodin-2 is an antagonist of tropomodulin-1 at the pointed end of the thin filaments in cardiac muscle by Tsukada, Takehiro, Pappas, Christopher T, Moroz, Natalia, Antin, Parker B, Kostyukova, Alla S, Gregorio, Carol C

“…Regulation of actin filament assembly is essential for efficient contractile activity in striated muscle. Leiomodin is an actin-binding protein and homolog of…”
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Serial viral infections in infants with recurrent respiratory illnesses by Jartti, T, Lee, W-M, Pappas, T, Evans, M, Lemanske, R. F., Jr, Gern, J. E

“…To better understand the viral aetiology of recurrent and prolonged illnesses, nasal secretions were prospectively collected from 285 infants at increased risk…”
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ERCP-related perforations: risk factors and management by Enns, R, Eloubeidi, M A, Mergener, K, Jowell, P S, Branch, M S, Pappas, T M, Baillie, J

“…Perforations during endoscopic retrograde cholangiopancreatography (ERCP) are rare, and the management of these perforations is variable, with some patients…”
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Laparoscopic distal pancreatectomy with splenic preservation by PRYOR, A, MEANS, J. R, PAPPAS, T. N

“…The technique of distal pancreatectomy has been well described, both with en bloc resection of the spleen and with splenic preservation. Splenic preservation…”
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Acute Effects Of Stretching On Leg And Vertical Stiffness During Treadmill Running by Pappas, Panagiotis, Paradisis, Giorgos P, Exell, Timothy A, Smirniotou, Athanasia, Tsolakis, Charilaos, Arampatzis, Adamantios

“…ABSTRACTThe implementation of static (SS) and dynamic (DS) stretching during warm-up routines produces significant changes in biological and functional…”
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Leiomodin 2 neonatal dilated cardiomyopathy mutation results in altered actin gene signatures and cardiomyocyte dysfunction by Iwanski, Jessika B., Pappas, Christopher T., Mayfield, Rachel M., Farman, Gerrie P., Ahrens-Nicklas, Rebecca, Churko, Jared M., Gregorio, Carol C.

“…Neonatal dilated cardiomyopathy (DCM) is a poorly understood muscular disease of the heart. Several homozygous biallelic variants in LMOD2 , the gene encoding…”
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A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults by Nobuhara, Chloe K., Bullock, W. Michael, Bunning, Thomas, Colin, Brian, Cooter, Mary, Devinney, Michael J., Ferrandino, Michael N., Gadsden, Jeffrey, Garrigues, Grant, Habib, Ashraf S., Moretti, Eugene, Moul, Judd, Ohlendorf, Brian, Sandler, Aaron, Scheri, Randall, Sharma, Bharat, Thomas, Jake P., Young, Christopher, Mathew, Joseph P., Berger, Miles

“…Objective Lumbar punctures (LPs) are important for obtaining CSF in neurology studies but are associated with adverse events and feared by many patients. We…”
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Reduced myofibrillar connectivity and increased Z-disk width in nebulin-deficient skeletal muscle by Tonino, Paola, Pappas, Christopher T, Hudson, Bryan D, Labeit, Siegfried, Gregorio, Carol C, Granzier, Henk

“…A prominent feature of striated muscle is the regular lateral alignment of adjacent sarcomeres. An important intermyofibrillar linking protein is the…”
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PB2302: HEPARIN‐INDUCED THROMBOCYTOPENIA ANTIBODIES CAN MAINTAIN PLATELET‐ACTIVATING PROPERTIES AFTER TWO SESSIONS OF THERAPEUTIC PLASMA EXCHANGE by Gkalea, V., Tseke, P., Pappas, T., Kotsiauti, A., Petrou, V., Psimenou, E., Matsouka, C.

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Endogenous acyl ghrelin is involved in mediating spontaneous phase III‐like contractions of the rat stomach by Ariga, H., Tsukamoto, K., Chen, C., Mantyh, C., Pappas, T. N., Takahashi, T.

“…In humans and dogs, it is known that motilin regulates phase III contractions of migrating motor complex (MMC) in the fasted state. In rats, however, motilin…”
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