Search Results - "Pappas, Danielle C"
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IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity
Published in Cancer discovery (01-07-2024)“…IL2 signals pleiotropically on diverse cell types, some of which contribute to therapeutic activity against tumors, whereas others drive undesired activity,…”
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An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity
Published in Cancer immunology research (01-10-2021)“…The use of cytokines for immunotherapy shows clinical efficacy but is frequently accompanied by severe adverse events caused by excessive and systemic immune…”
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Targeting OX40 by monoclonal antibody PF-04518600 to enhance T cell functions and inhibit tumor growth
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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