Search Results - "Papp, Diana"
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Morphogen Signals Shaping the Gastric Glands in Health and Disease
Published in International journal of molecular sciences (26-03-2022)“…The adult gastric mucosa is characterised by deep invaginations of the epithelium called glands. These tissue architectural elements are maintained with the…”
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The primary function of Six5 of Fusarium oxysporum is to facilitate Avr2 activity by together manipulating the size exclusion limit of plasmodesmata
Published in Frontiers in plant science (29-07-2022)“…Pathogens produce effector proteins to manipulate their hosts. While most effectors act autonomously, some fungal effectors act in pairs and rely on each other…”
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Studies on the interactions between C-reactive protein and complement proteins
Published in Immunology (01-05-2007)“…Several studies have investigated the interactions between C-reactive protein (CRP) and various complement proteins but none of them took into consideration…”
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A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans
Published in PLoS pathogens (01-04-2012)“…A proper immune response ensures survival in a hostile environment and promotes longevity. Recent evidence indicates that innate immunity, beyond antimicrobial…”
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The heat shock connection of metabolic stress and dietary restriction
Published in Current pharmaceutical biotechnology (01-02-2010)“…Molecular chaperones and the heat shock response guard and modulate protein conformation, protect proteins from misfolding and aggregation, and maintain…”
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Revolutionizing immune research with organoid-based co-culture and chip systems
Published in Clinical and experimental immunology (16-09-2024)“…The intertwined interactions various immune cells have with epithelial cells in our body require sophisticated experimental approaches to be studied. Due to…”
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Systems-Level Feedbacks of NRF2 Controlling Autophagy upon Oxidative Stress Response
Published in Antioxidants (05-03-2018)“…Although the primary role of autophagy-dependent cellular self-eating is cytoprotective upon various stress events (such as starvation, oxidative stress, and…”
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The NRF2-related interactome and regulome contain multifunctional proteins and fine-tuned autoregulatory loops
Published in FEBS letters (21-06-2012)“…► We present a systems-level resource for NRF2 studies. ► Following manual curation we found 79 NRF2 interactors and 29 NRF2 target genes. ► We predict 116…”
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Comparative phyloproteomics identifies conserved plasmodesmal proteins
Published in Journal of experimental botany (28-03-2023)“…Abstract Plasmodesmata are cytosolic bridges, lined by the plasma membrane and traversed by endoplasmic reticulum; plasmodesmata connect cells and tissues, and…”
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AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects
Published in Autophagy (01-01-2016)“…Autophagy is a major molecular mechanism that eliminates cellular damage in eukaryotic organisms. Basal levels of autophagy are required for maintaining…”
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A PDLP-NHL3 complex integrates plasmodesmal immune signaling cascades
Published in Proceedings of the National Academy of Sciences - PNAS (25-04-2023)“…The plant immune system relies on the perception of molecules that signal the presence of a microbe threat. This triggers signal transduction that mediates a…”
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The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms
Published in Scientific reports (16-02-2017)“…Autophagy functions as a main route for the degradation of superfluous and damaged constituents of the cytoplasm. Defects in autophagy are implicated in the…”
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Everything You Always Wanted to Know About Organoid-Based Models (and Never Dared to Ask)
Published in Cellular and molecular gastroenterology and hepatology (01-01-2022)“…Homeostatic functions of a living tissue, such as the gastrointestinal tract, rely on highly sophisticated and finely tuned cell-to-cell interactions. These…”
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NRF2-ome : An Integrated Web Resource to Discover Protein Interaction and Regulatory Networks of NRF2
Published in Oxidative medicine and cellular longevity (01-01-2013)“…NRF2 is the master transcriptional regulator of oxidative and xenobiotic stress responses. NRF2 has important roles in carcinogenesis, inflammation, and…”
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Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage
Published in Free radical biology & medicine (15-10-2011)“…The superoxide free radical (O2•−) has been viewed as a likely major contributor to aging. If this is correct, then superoxide dismutase (SOD), which removes…”
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Suppression of AMPK/aak‐2 by NRF2/SKN‐1 down‐regulates autophagy during prolonged oxidative stress
Published in The FASEB journal (01-02-2019)“…ABSTRACT NF‐E2‐related factor 2 (NRF2) transcription factor has a fundamental role in cell homeostasis maintenance as one of the master regulators of oxidative…”
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Diffusion and bulk flow of amino acids mediate calcium waves in plants
Published in Science advances (21-10-2022)“…In plants, a variety of stimuli trigger long-range calcium signals that travel rapidly along the vasculature to distal tissues via poorly understood…”
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Development of a sensitive assay for the measurement of antibodies against heat shock protein binding protein 1 (HspBP1): Increased levels of anti-HspBP1 IgG are prevalent in HIV infected subjects
Published in Journal of medical virology (01-08-2005)“…The 70 kDa heat shock protein (Hsp70) is generally considered to be an intracellular protein, however, there is evidence that Hsp70 can be found in the…”
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AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects
Published in Autophagy (01-02-2016)“…Autophagy is a major molecular mechanism that eliminates cellular damage in eukaryotic organisms. Basal levels of autophagy are required for maintaining…”
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