Search Results - "Papoutsis, Andreas J."

n-6 High Fat Diet Induces Gut Microbiome Dysbiosis and Colonic Inflammation by Selmin, Ornella I., Papoutsis, Andreas J., Hazan, Sabine, Smith, Christopher, Greenfield, Nick, Donovan, Micah G., Wren, Spencer N., Doetschman, Thomas C., Snider, Justin M., Snider, Ashley J., Chow, Sherry H.-H., Romagnolo, Donato F.

“…Background: Concerns are emerging that a high-fat diet rich in n-6 PUFA (n-6HFD) may alter gut microbiome and increase the risk of intestinal disorders…”
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Lost microbes of COVID-19: Bifidobacterium, Faecalibacterium depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severity by Hazan, Sabine, Stollman, Neil, Bozkurt, Huseyin S, Dave, Sonya, Papoutsis, Andreas J, Daniels, Jordan, Barrows, Brad D, Quigley, Eamonn MM, Borody, Thomas J

“…ObjectiveThe study objective was to compare gut microbiome diversity and composition in SARS-CoV-2 PCR-positive patients whose symptoms ranged from…”
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Targeting of aryl hydrocarbon receptor-mediated activation of cyclooxygenase-2 expression by the indole-3-carbinol metabolite 3,3'-diindolylmethane in breast cancer cells by Degner, Stephanie C, Papoutsis, Andreas J, Selmin, Ornella, Romagnolo, Donato F

“…Ligands of the aryl hydrocarbon receptor (AhR) include the environmental xenobiotic 2,3,7,8 tetrachlorodibenzo(p)dioxin (TCDD), polycyclic aryl hydrocarbons,…”
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BRCA-1 promoter hypermethylation and silencing induced by the aromatic hydrocarbon receptor-ligand TCDD are prevented by resveratrol in MCF-7 Cells by Papoutsis, Andreas J, Borg, Jamie L, Selmin, Ornella I, Romagnolo, Donato F

“…Epigenetic mechanisms may contribute to reduced expression of the tumor suppressor gene BRCA-1 in sporadic breast cancers. Through environmental exposure and…”
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Gestational exposure to the AhR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin induces BRCA-1 promoter hypermethylation and reduces BRCA-1 expression in mammary tissue of rat offspring: Preventive effects of resveratrol by Papoutsis, Andreas J., Selmin, Ornella I., Borg, Jamie L., Romagnolo, Donato F.

“…Studies with murine models suggest that maternal exposure to aromatic hydrocarbon receptor (AhR) agonists may impair mammary gland differentiation and increase…”
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Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells by Papoutsis, Andreas J, Lamore, Sarah D, Wondrak, Georg T, Selmin, Ornella I, Romagnolo, Donato F

“…The BRCA-1 protein is a tumor suppressor involved in repair of DNA damage. Epigenetic mechanisms contribute to its reduced expression in sporadic breast…”
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Constitutive expression of AhR and BRCA-1 promoter CpG hypermethylation as biomarkers of ERα-negative breast tumorigenesis by Romagnolo, Donato F, Papoutsis, Andreas J, Laukaitis, Christina, Selmin, Ornella I

“…Only 5-10% of breast cancer cases is linked to germline mutations in the BRCA-1 gene and occurs early in life. Conversely, sporadic breast tumors, which…”
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Vitamin C improves gut Bifidobacteria in humans by Hazan, Sabine, Dave, Sonya, Papoutsis, Andreas J, Deshpande, Nirupama, Howell, Jr, Mark C, Martin, Leisha Ma

“…Numerous beneficial effects of vitamin C (ascorbic acid) supplementation have been reported in the literature. However, data on its effects toward the gut…”
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Genistein Prevents BRCA1 CpG Methylation and Proliferation in Human Breast Cancer Cells with Activated Aromatic Hydrocarbon Receptor by Romagnolo, Donato F, Donovan, Micah G, Papoutsis, Andreas J, Doetschman, Tom C, Selmin, Ornella I

“…Previous studies have suggested a causative role for agonists of the aromatic hydrocarbon receptor (AhR) in the etiology of breast cancer 1, early-onset…”
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Successful Bacterial Engraftment Identified by Next-Generation Sequencing Predicts Success of Fecal Microbiota Transplant for Clostridioides difficile by Hazan, Sabine, Dave, Sonya, Papoutsis, Andreas J, Barrows, Brad D, Borody, Thomas J

“…The effectiveness of fecal microbiota transplantation (FMT), a treatment for infection (CDI), is dependent on successful engraftment (incorporation) of donor…”
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Trichloroethylene Induces Methylation of the Serca2 Promoter in H9c2 Cells and Embryonic Heart by Palbykin, Brittany, Borg, Jamie, Caldwell, Patricia T., Rowles, Josh, Papoutsis, Andreas J., Romagnolo, Donato F., Selmin, Ornella I.

“…Trichloroethylene (TCE) is a halogenated hydrocarbon used as a solvent in industrial settings and in house-cleaning products. Exposure to TCE has been linked…”
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Abstract 4318: Reversal of BRCA-1 CpG hyperthylation by genistein and (-)-epigallocatechin-3-gallate in human breast cancer cells with activated AhR by Selmin, Ornella I., Papoutsis, Andreas J., Romagnolo, Donato F.

“…Abstract Sporadic breast cancers, which represent the vast majority (∼90%) of breast tumor cases, do not have mutations in the tumor suppressor gene, BRCA-1…”
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Reversal Effects of Genistein and (−)‐Epigallocatechin‐3‐Gallate on Repression of BRCA‐1 Expression in Human Breast Cancer Cells with Activated AhR by Selmin, Ornella I, Papoutsis, Andreas J, Romagnolo, Donato F

“…Abstract only Sporadic breast cancers, which represent the vast majority (~90%) of breast tumor cases, do not have mutations in the tumor suppressor gene,…”
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Constitutive expression of AhR and BRCA-1 promoter CpG hypermethylation as biomarkers of ER[alpha]-negative breast tumorigenesis by Romagnolo, Donato F, Papoutsis, Andreas J, Laukaitis, Christina, Selmin, Ornella I

“…Background Only 5-10 % of breast cancer cases is linked to germline mutations in the BRCA-1 gene and occurs early in life. Conversely, sporadic breast tumors,…”
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Regulation of BRCA‐1 by Xenobiotic and Dietary Ligands of the Aryl Hydrocarbon Receptor by Papoutsis, Andreas J, Romagnolo, Donato F

“…Abstract only The BRCA‐1 protein is involved in repair of DNA damage and mutations of the BRCA‐1 gene confer a high risk of developing breast cancer…”
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Abstract 1115: Epigenetic regulation of BRCA-1 by xenobiotic and dietary ligands of the aryl hydrocarbon receptor by Romagnolo, Donato F., Selmin, Ornella I., Papoutsis, Andreas J.

“…Abstract Mutations of BRCA-1 account for only 5-10% of breast cancer cases, whereas sporadic breast tumors represent the remaining 90-95%. In sporadic breast…”
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Constitutive expression of AhR and BRCA-1 promoter CpG hypermethylation as biomarkers of ERAlpha-negative breast tumorigenesis by Romagnolo, Donato F, Papoutsis, Andreas J, Laukaitis, Christina, Selmin, Ornella I

“…Background Only 5-10 % of breast cancer cases is linked to germline mutations in the BRCA-1 gene and occurs early in life. Conversely, sporadic breast tumors,…”
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Nutritional targeting of cyclooxygenase-2 for colon cancer prevention by Romagnolo, Donato F, Papoutsis, Andreas J, Selmin, Ornella

“…Factors related to diet and life style have been identified as primary determinants in about 80% of colorectal cancers. Non-steroidal anti-inflammatory drugs…”
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Health Benefits of Traditional Culinary and Medicinal Mediterranean Plants

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Chapter 26 - Health Benefits of Traditional Culinary and Medicinal Mediterranean Plants by Degner, Stephanie C., Papoutsis, Andreas J., Romagnolo, Donato F.

“…This chapter focuses on the health benefits of traditional culinary and medicinal plants of the Mediterranean region. The Mediterranean diet is mentioned to be…”
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