Search Results - "Papich, Mark G"
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Pharmacokinetic–pharmacodynamic (PK–PD) modeling and the rational selection of dosage regimes for the prudent use of antimicrobial drugs
Published in Veterinary microbiology (16-07-2014)“…One of the strategies to decrease inappropriate antimicrobial use in veterinary medicine is to apply pharmacokinetic–pharmacodynamic (PK–PD) principles to…”
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Applying Biopharmaceutical Classification System (BCS) Criteria to Predict Oral Absorption of Drugs in Dogs: Challenges and Pitfalls
Published in The AAPS journal (01-07-2015)“…The Biopharmaceutical Classification System (BCS) has been a prognostic tool for assessing the potential effects of formulation on the human drug oral…”
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Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target
Published in Antimicrobial Agents and Chemotherapy (01-06-2012)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Role of electrolyte concentrations and renin‐angiotensin‐aldosterone activation in the staging of canine heart disease
Published in Journal of veterinary internal medicine (01-01-2020)“…Background Refractory congestive heart failure (CHF) and associated diuretic resistance are not well defined. Objectives To characterize renal function,…”
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Antimicrobials, susceptibility testing, and minimum inhibitory concentrations (MIC) in veterinary infection treatment
Published in The Veterinary clinics of North America. Small animal practice (01-09-2013)“…Veterinarians are quick to attribute an unsuccessful antimicrobial treatment to a failure of the culture and susceptibility test. There are many reasons why…”
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Guidelines for the diagnosis and antimicrobial therapy of canine superficial bacterial folliculitis (Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases)
Published in Veterinary dermatology (01-06-2014)“…Background Superficial bacterial folliculitis (SBF) is usually caused by Staphylococcus pseudintermedius and routinely treated with systemic antimicrobial…”
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Considerations for using minocycline vs doxycycline for treatment of canine heartworm disease
Published in Parasites & vectors (09-11-2017)“…Doxycycline has been considered the first drug of choice for treating Wolbachia, a member of the Rickettsiaceae, which has a symbiotic relationship with…”
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Evaluation of bioabsorbable calcium sulfate hemihydrate beads for local delivery of carboplatin
Published in PloS one (05-11-2020)“…The objectives of this study were to evaluate a novel kit of resorbable calcium sulfate beads marketed specifically for use in veterinary medicine and…”
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Population pharmacokinetic analysis of enrofloxacin and its active metabolite ciprofloxacin after intravenous injection to cats with reduced kidney function
Published in Journal of veterinary internal medicine (01-11-2023)“…Background It is unknown if enrofloxacin accumulates in plasma of cats with reduced kidney function. Hypothesis To determine if enrofloxacin and its active…”
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Pharmacokinetics of pimobendan after oral administration to dogs with myxomatous mitral valve disease
Published in Journal of veterinary internal medicine (01-11-2023)“…Background Pimobendan is an important therapy for dogs with myxomatous mitral valve disease (MMVD). The pharmacokinetics are reported in healthy dogs but not…”
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Pharmacodynamics of Doxycycline and Tetracycline against Staphylococcus pseudintermedius: Proposal of Canine-Specific Breakpoints for Doxycycline
Published in Journal of Clinical Microbiology (01-11-2013)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Ampicillin pharmacokinetics in azotemic and healthy dogs
Published in Journal of veterinary internal medicine (01-03-2021)“…Background Little is known about effects of factors such as kidney disease, affecting ampicillin pharmacokinetics in dogs. Objectives Determine the…”
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The effect of enrofloxacin on enteric Escherichia coli: Fitting a mathematical model to in vivo data
Published in PloS one (31-01-2020)“…Antimicrobial drugs administered systemically may cause the emergence and dissemination of antimicrobial resistance among enteric bacteria. To develop logical,…”
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Analysis of US Marketed Artemisinin Supplements for Use in Dogs
Published in Journal of veterinary pharmacology and therapeutics (24-08-2024)“…Oral artemisinin has antiparasitic activity and may help improve treatment success rates in dogs infected with Babesia gibsoni. However, these artemisinin…”
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Response to Correspondence on 'Analysis of US Marketed Artemisinin Supplements for Use in Dogs'
Published in Journal of veterinary pharmacology and therapeutics (14-10-2024)Get full text
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Evaluation of urine concentrations of amoxicillin and clavulanate in cats
Published in Journal of veterinary internal medicine (01-01-2021)“…Background To characterize urinary isolates, the Clinical and Laboratory Standards Institute (CLSI) uses an amoxicillin breakpoint for cats based on plasma…”
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The effect of combined carprofen and omeprazole administration on gastrointestinal permeability and inflammation in dogs
Published in Journal of veterinary internal medicine (01-09-2020)“…Background Proton pump inhibitors (eg, omeprazole) commonly are administered concurrently with nonsteroidal anti‐inflammatory drugs (NSAIDs; eg, carprofen) as…”
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Comparison of Active Drug Concentrations in the Pulmonary Epithelial Lining Fluid and Interstitial Fluid of Calves Injected with Enrofloxacin, Florfenicol, Ceftiofur, or Tulathromycin
Published in PloS one (12-02-2016)“…Bacterial pneumonia is the most common reason for parenteral antimicrobial administration to beef cattle in the United States. Yet there is little information…”
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Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers
Published in PloS one (04-10-2019)“…Antimicrobial drug concentrations in the gastrointestinal tract likely drive antimicrobial resistance in enteric bacteria. Our objective was to determine the…”
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Patterns of antimicrobial drug use in veterinary primary care and specialty practice: A 6‐year multi‐institution study
Published in Journal of veterinary internal medicine (01-05-2021)“…Background Combatting antimicrobial resistance requires a One Health approach to antimicrobial stewardship including antimicrobial drug (AMD) use evaluation…”
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