Search Results - "Papeta, Natalia"

Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice by Papeta, Natalia, Zheng, Zongyu, Schon, Eric A, Brosel, Sonja, Altintas, Mehmet M, Nasr, Samih H, Reiser, Jochen, D'Agati, Vivette D, Gharavi, Ali G

“…Adriamycin (ADR) is a commonly used chemotherapeutic agent that also produces significant tissue damage. Mutations to mitochondrial DNA (mtDNA) and reductions…”
Get full text

Refinement of the HIVAN1 Susceptibility Locus on Chr. 3A1-A3 via Generation of Sub-Congenic Strains by Papeta, Natalia, Patel, Ami, D'Agati, Vivette D, Gharavi, Ali G

“…HIV-1 transgenic mice on the FVB/NJ background (TgFVB) represent a validated model of HIV-associated nephropathy (HIVAN). A major susceptibility locus, HIVAN1,…”
Get full text

Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression by Papeta, Natalia, Chan, Ka-Tak, Prakash, Sindhuri, Martino, Jeremiah, Kiryluk, Krzysztof, Ballard, David, Bruggeman, Leslie A, Frankel, Rachelle, Zheng, Zongyu, Klotman, Paul E, Zhao, Hongyu, D'Agati, Vivette D, Lifton, Richard P, Gharavi, Ali G

“…Multiple studies have linked podocyte gene variants to diverse sporadic nephropathies, including HIV-1-associated nephropathy (HIVAN). We previously used…”
Get full text

A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse by Lugani, Francesca, Arora, Ripla, Papeta, Natalia, Patel, Ami, Zheng, Zongyu, Sterken, Roel, Singer, Ruth A, Caridi, Gianluca, Mendelsohn, Cathy, Sussel, Lori, Papaioannou, Virginia E, Gharavi, Ali G

“…Danforth's short tail mutant (Sd) mouse, first described in 1930, is a classic spontaneous mutant exhibiting defects of the axial skeleton, hindgut, and…”
Get full text

Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling by Shkreli, Marina, Sarin, Kavita Y, Pech, Matthew F, Papeta, Natalia, Chang, Woody, Brockman, Stephanie A, Cheung, Peggie, Lee, Eunice, Kuhnert, Frank, Olson, Jean L, Kuo, Calvin J, Gharavi, Ali G, D'Agati, Vivette D, Artandi, Steven E

“…Steven Artandi and his colleagues have found that dedifferentiation and proliferation of kidney podocytes as a result of TERT or Wnt signaling leads to a…”
Get full text

Mutations in DSTYK and Dominant Urinary Tract Malformations by Sanna-Cherchi, S, Sampogna, R.V, Papeta, N, Burgess, K.E, Nees, S.N, Perry, B.J, Choi, M, Bodria, M, Liu, Y, Weng, P.L, Lozanovski, V.J, Verbitsky, M, Lugani, F, Sterken, R, Paragas, N, Caridi, G, Carrea, A, Dagnino, M, Materna-Kiryluk, A, Santamaria, G, Murtas, C, Ristoska-Bojkovska, N, Izzi, C, Kacak, N, Bianco, B, Giberti, S, Gigante, M, Piaggio, G, Gesualdo, L, Kosuljandic Vukic, D, Vukojevic, K, Saraga-Babic, M, Saraga, M, Gucev, Z, Allegri, L, Latos-Bielenska, A, Casu, D, State, M, Scolari, F, Ravazzolo, R, Kiryluk, K, Al-Awqati, Q, D'Agati, V.D, Drummond, I.A, Tasic, V, Lifton, R.P, Ghiggeri, G.M, Gharavi, A.G

“…Exome sequencing in a family with autosomal dominant congenital urinary tract malformations showed a mutation in dual serine–threonine and tyrosine protein…”
Get full text

APOL1 Variants Increase Risk for FSGS and HIVAN but Not IgA Nephropathy by PAPETA, Natalia, KIRYLUK, Krzysztof, WYATT, Robert J, NOVAK, Jan, WYATT, Christina M, ROSS, Michael J, WINSTON, Jonathan A, KLOTMAN, Mary E, COHEN, David J, APPEL, Gerald B, D'AGATI, Vivette D, KLOTMAN, Paul E, PATEL, Ami, GHARAVI, Ali G, STERKEN, Roel, KACAK, Nilgun, SNYDER, Holly J, IMUS, Phil H, MHATRE, Anand N, LAWANI, Anil K, JULIAN, Bruce A

“…A chromosome 22q13 locus strongly associates with increased risk for idiopathic focal segmental glomerulosclerosis (FSGS), HIV-1-associated nephropathy…”
Get full text

S-Nitrosylation of Mitochondrial Caspases by Mannick, Joan B., Schonhoff, Christopher, Papeta, Natalia, Ghafourifar, Pedram, Szibor, Marten, Fang, Kezhong, Gaston, Benjamin

“…Caspase-3 is a cysteine protease located in both the cytoplasm and mitochondrial intermembrane space that is a central effector of many apoptotic pathways. In…”
Get full text

The molecular pathogenesis of HIV-1 associated nephropathy: recent advances by Papeta, Natalia, Sterken, Roel, Kiryluk, Krzysztof, Kalyesubula, Robert, Gharavi, Ali G.

“…HIV-1-associated nephropathy (HIVAN) is a major complication of HIV-1 infection, frequently resulting in kidney failure. HIVAN arises due to HIV-1-induced…”
Get full text

Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-Derived Factor-1/CXCL12 Induce Tumor-Specific T Cell Chemorepulsion and Escape from Immune Control by Vianello, Fabrizio, Papeta, Natalia, Chen, Tao, Kraft, Paul, White, Natasha, Hart, William K, Kircher, Moritz F, Swart, Eric, Rhee, Sarah, Palu, Giorgio, Irimia, Daniel, Toner, Mehmet, Weissleder, Ralph, Poznansky, Mark C

“…The chemokine, stromal-derived factor-1/CXCL12, is expressed by normal and neoplastic tissues and is involved in tumor growth, metastasis, and modulation of…”
Get full text

Accelerated development of collapsing glomerulopathy in mice congenic for the HIVAN1 locus by Chan, Ka T., Papeta, Natalia, Martino, Jeremiah, Zheng, Zongyu, Frankel, Rachelle Z., Klotman, Paul E., D'Agati, Vivette D., Lifton, Richard P., Gharavi, Ali G.

“…HIV-1 transgenic mice on the FVB/NJ background (TgFVB) are a well validated model of HIV-associated nephropathy (HIVAN). A mapping study between TgFVB and…”
Get full text

Identification of the Nephropathy-Susceptibility Locus HIVAN4 by PRAKASH, Sindhuri, PAPETA, Natalia, STERKEN, Roel, ZONGYU ZHENG, THOMAS, Robert L, ZHENZHEN WE, SEDOR, John R, D'AGATI, Vivette D, BRUGGEMAN, Leslie A, GHARAVI, Ali G

“…HIVAN1, HIVAN2, and HIVAN3 are nephropathy-susceptibility loci previously identified in the HIV-1 transgenic mouse, a model of collapsing glomerulopathy. The…”
Get full text

Long-term survival of transplanted allogeneic cells engineered to express a T cell chemorepellent by PAPETA, Natalia, TAO CHEN, YOON, Victor, SYKES, Megan, SACHS, David, IACOTNINI, John, POZNANSKY, Mark C, VIANELLO, Fabrizio, GERERTY, Lyle, MALIK, Ashish, MOK, Ying-Ting, THARP, William G, BAGLEY, Jessamyn, GUILING ZHAO, STEVCEVA, Liljana

“…Alloantigen specific T cells have been shown to be required for allograft rejection. The chemokine, stromal cell derived factor-1 (SDF-1) at high…”
Get full text

Accelerated Development of Collapsing Glomerulopathy in Mice Congenic for the HIVAN1 locus on chr 3A1-A3 by Chan, Ka Tak, Papeta, Natalia, Martino, Jeremiah, Zheng, Zongyu, Frankel, Rachelle, Klotman, Paul E., D’Agati, Vivette D., Lifton, Richard P., Gharavi, Ali G.

“…HIV-1 transgenic mice on the FVB/NJ background (TgFVB) represent a well-validated model of HIV-associated nephropathy (HIVAN). A mapping study between TgFVB…”
Get full text

A Retrotransposon Insertion in the 5' Regulatory Domain of Ptf1a Results in Ectopic Gene Expression and Multiple Congenital Defects in Danforth's Short Tail Mouse. e1003206 by Lugani, Francesca, Arora, Ripla, Papeta, Natalia, Patel, Ami, Zheng, Zongyu, Sterken, Roel, Singer, Ruth A, Caridi, Gianluca, Mendelsohn, Cathy, Sussel, Lori

“…Danforth's short tail mutant (Sd) mouse, first described in 1930, is a classic spontaneous mutant exhibiting defects of the axial skeleton, hindgut, and…”
Get full text

Murine Melanomas Expressing High Levels of SDF-1 Repel and Escape Control by Tumor Specific T-Cells by Vianello, Fabrizio, Papeta, Natalia, Kircher, Moritz F., Toner, Mehmet, Weissleder, Ralph, Irimia, Daniel, Poznansky, Mark C.

“…Most antigenic tumors are able to evade the immune system despite T cell recognition of tumor specific antigens. The chemokine, stromal derived factor- 1…”
Get full text