Search Results - "Pape, Felix"
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Probing the Origin of Affinity in the GM1-Cholera Toxin Complex through Site-Selective Editing with Fluorine
Published in ACS central science (28-08-2024)“…Carbohydrates regulate an inimitable spectrum of biological functions, yet successfully leveraging this therapeutic avenue continues to be frustrated by low…”
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Photocatalytic E → Z Isomerization of β‑Ionyl Derivatives
Published in Organic letters (06-12-2019)“…An operationally simple E → Z isomerization of activated dienes, based on the β-ionyl motif intrinsic to retinal, is reported using inexpensive (−)-riboflavin…”
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Dealing at Arm's Length: Catalysis with N‐Heterocyclic Carbene Ligands Bearing Anionic Tethers
Published in European journal of organic chemistry (10-08-2017)“…The catalytic transformations enabled by bidentate N‐heterocyclic carbenes bearing anionic substituents (tethered NHCs) are presented. The use of tethered NHCs…”
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Z-Selective Copper(I)-Catalyzed Alkyne Semihydrogenation with Tethered Cu-Alkoxide Complexes
Published in Chemistry : a European journal (02-11-2015)“…A highly stereoselective alkyne semihydrogenation with copper(I) complexes is reported. Copper–N‐heterocyclic carbene complex catalysts, bearing an…”
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Application of Lithiation–Borylation to the Total Synthesis of (−)-Rakicidin F
Published in Organic letters (30-12-2022)“…The stereochemistry of the lipophilic side chain of (+)-rakicidin F had not been determined until recently. Using our lithiation–borylation methodology…”
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Conventional displays of structures in data compared with interactive projection-based clustering (IPBC)
Published in International journal of data science and analytics (01-09-2021)“…Clustering is an important task in knowledge discovery with the goal to identify structures of similar data points in a dataset. Here, the focus lies on…”
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Catalytic Generation and Chemoselective Transfer of Nucleophilic Hydrides from Dihydrogen
Published in Chemistry : a European journal (18-01-2019)“…Copper(I)–N‐heterocyclic‐carbene (NHC) complexes enabled the catalytic generation of nucleophilic hydrides from dihydrogen (H2) and their subsequent transfer…”
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We are MedChem: The Frontiers in Medicinal Chemistry 2024
Published in ChemMedChem (23-09-2024)“…The Frontiers in Medicinal Chemistry (FiMC) is the largest international Medicinal Chemistry conference in Germany and took place from March 17 to 20 2024 in…”
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Back in Person: Frontiers in Medicinal Chemistry 2023
Published in ChemMedChem (04-10-2023)“…The Frontiers in Medicinal Chemistry (FiMC) is the largest international Medicinal Chemistry conference in the German speaking area and took place from April 3…”
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Copper(I)-Catalyzed Allylic Substitutions with a Hydride Nucleophile
Published in Organic letters (20-05-2016)“…An easily accessible copper(I)/N-heterocyclic carbene (NHC) complex enables a regioselective hydride transfer to allylic bromides, an allylic reduction. The…”
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Interactive Machine Learning Tool for Clustering in Visual Analytics
Published in 2020 IEEE 7th International Conference on Data Science and Advanced Analytics (DSAA) (01-10-2020)“…Clustering is an important task in knowledge discovery with the goal of finding groups of similar data points in a dataset. Today there are many different…”
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