Magnitude of reactive thrombocytosis and associated clinical conditions in dogs

Magnitude of reactive thrombocytosis and associated clinical conditions in dogs

Previous studies on the underlying causes of thrombocytosis have raised scientific interest in its clinical relevance in dogs. The purpose of this study was: (1) to explore the clinical conditions associated with thrombocytosis; (2) to compare platelet counts among these conditions; and (3) to ident...

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Bibliographic Details
Published in:Veterinary record Vol. 181; no. 10; p. 267
Main Authors: Athanasiou, Labrini V, Polizopoulou, Zoe S, Papavasileiou, Eleftheria G, Mpairamoglou, Efstathios L, Kantere, Maria C, Rousou, Xanthi A
Format: Journal Article
Language:English
Published: England BMJ Publishing Group Limited 01-09-2017
Blackwell Publishing Ltd
Subjects:
anaemia
Anemia
Anemia - diagnosis
Anemia - veterinary
Animals
Blood Cell Count - veterinary
Blood platelets
Cats
Diagnosis, Differential
dog
Dog Diseases - diagnosis
Dogs
Family medical history
Female
Geriatrics
Hematology
inflammation
Liver cancer
Male
Medical records
Multivariate analysis
neoplasia
Neoplasms - diagnosis
Neoplasms - veterinary
Platelet Count - veterinary
platelets
Prevalence
reactive thrombocytosis
Thrombocytosis - complications
Thrombocytosis - epidemiology
Thrombocytosis - veterinary
Variables
Veterinary medicine
anaemia
inflammation
dog
reactive thrombocytosis
neoplasia
platelets
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Summary:Previous studies on the underlying causes of thrombocytosis have raised scientific interest in its clinical relevance in dogs. The purpose of this study was: (1) to explore the clinical conditions associated with thrombocytosis; (2) to compare platelet counts among these conditions; and (3) to identify possible interactions with other haematological variables and associated conditions. Medical records of 195 dogs with thrombocytosis (platelet count >500×103/μL) were reviewed for signalment, complete blood count results and definitive diagnosis. The prevalence of thrombocytosis was 6.02%. All cases included had reactive thrombocytosis, with non-neoplastic, non-inflammatory underlying conditions in 48.2%, inflammatory processes in 34.4% and neoplastic processes in 17.4%. Haemoglobin and white blood cell counts were negatively and positively associated with platelet count, respectively. This study revealed that mean platelet count in dogs with neoplasia and a packed cell volume of 35% or below was significantly higher than that for dogs with other disease categories. Therefore, for dogs with marked thrombocytosis and anaemia, it is recommended that neoplasia should be included in the list of differential diagnoses.
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SourceType-Scholarly Journals-1
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ISSN:0042-4900
2042-7670
DOI:10.1136/vr.104042