Search Results - "Papatheodorou, Angelos"
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Activin A more prominently regulates muscle mass in primates than does GDF8
Published in Nature communications (28-04-2017)“…Growth and differentiation factor 8 (GDF8) is a TGF-β superfamily member, and negative regulator of skeletal muscle mass. GDF8 inhibition results in prominent…”
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Inflammation induces irreversible biophysical changes in isolated nucleus pulposus cells
Published in PloS one (17-06-2014)“…Intervertebral disc degeneration is accompanied by elevated levels of inflammatory cytokines that have been implicated in disease etiology and matrix…”
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Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity
Published in Proceedings of the National Academy of Sciences - PNAS (21-06-2011)“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of pathogenic autoantibodies, many of which are directed…”
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Age and Other Risk Factors Influencing Long-Term Mortality in Patients With Traumatic Cervical Spine Fracture
Published in Geriatric orthopaedic surgery & rehabilitation (2018)“…Objective: To identify clinical or demographic variables that influence long-term mortality, as well as in-hospital mortality, with a particular focus on the…”
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High-Mobility Group Box 1 (HMGB1) Is Elevated Systemically in Persons with Acute or Chronic Traumatic Spinal Cord Injury
Published in Journal of neurotrauma (01-02-2017)“…Inflammation in traumatic spinal cord injury (SCI) has been proposed to promote damage acutely and oppose functional recovery chronically. However, we do not…”
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Elevated levels of IgA and IgG2 in individuals with chronic spinal cord injury
Published in The journal of spinal cord medicine (03-09-2022)“…To determine circulating levels of antibodies (IgA, IgM, IgG1-4) in individuals with SCI as compared to uninjured individuals. Prospective, observational…”
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Highly conserved molecular pathways, including Wnt signaling, promote functional recovery from spinal cord injury in lampreys
Published in Scientific reports (15-01-2018)“…In mammals, spinal cord injury (SCI) leads to dramatic losses in neurons and synaptic connections, and consequently function. Unlike mammals, lampreys are…”
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Amending HIV Drugs: A Novel Small-Molecule Approach To Target Lupus Anti-DNA Antibodies
Published in Journal of medicinal chemistry (13-10-2016)“…Systemic lupus erythematosus is an autoimmune disease that can affect numerous tissues and is characterized by the production of nuclear antigen-directed…”
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