Search Results - "Papas, Brian N."

UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin by Saini, Natalie, Giacobone, Camille K, Klimczak, Leszek J, Papas, Brian N, Burkholder, Adam B, Li, Jian-Liang, Fargo, David C, Bai, Re, Gerrish, Kevin, Innes, Cynthia L, Schurman, Shepherd H, Gordenin, Dmitry A

“…Human skin is continuously exposed to environmental DNA damage leading to the accumulation of somatic mutations over the lifetime of an individual. Mutagenesis…”
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Developmental estrogen exposure in mice disrupts uterine epithelial cell differentiation and causes adenocarcinoma via Wnt/β-catenin and PI3K/AKT signaling by Padilla-Banks, Elizabeth, Jefferson, Wendy N, Papas, Brian N, Suen, Alisa A, Xu, Xin, Carreon, Diana V, Willson, Cynthia J, Quist, Erin M, Williams, Carmen J

“…Tissue development entails genetically programmed differentiation of immature cell types to mature, fully differentiated cells. Exposure during development to…”
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Essential role of Mg2+ in mouse preimplantation embryo development revealed by TRPM7 chanzyme-deficient gametes by Gupta, Neha, Soriano-Úbeda, Cristina, Stein, Paula, Savy, Virginia, Papas, Brian N., Ardestani, Goli, Carvacho, Ingrid, Alfandari, Dominique, Williams, Carmen J., Fissore, Rafael A.

“…TRPM7 (transient receptor potential cation channel subfamily M member 7) is a chanzyme with channel and kinase domains essential for embryo development. Using…”
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TUT4/7-mediated uridylation of a coronavirus subgenomic RNAs delays viral replication by Gupta, Ankit, Li, Yin, Chen, Shih-Heng, Papas, Brian N., Martin, Negin P., Morgan, Marcos

“…Coronaviruses are positive-strand RNA viruses with 3′ polyadenylated genomes and subgenomic transcripts. The lengths of the viral poly(A) tails change during…”
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A unique poly(A) tail profile uncovers the stability and translational activation of TOP transcripts during neuronal differentiation by Baptissart, Marine, Papas, Brian N., Chi, Ru-pin Alicia, Li, Yin, Lee, Dongwon, Puviindran, Bhairavy, Morgan, Marcos

“…Cell differentiation is associated with global changes in translational activity. Here, we characterize how mRNA poly(A) tail processing supports this dynamic…”
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Interplay of Permanent Charge and Hydrophobicity in the Electrospray Ionization of Glycans by Walker, S. Hunter, Papas, Brian N, Comins, Daniel L, Muddiman, David C

“…The analysis of N-linked glycans by mass spectrometry (MS) has been characterized by low signal-to-noise ratios and high limits of detection due to their…”
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Patterns, Profiles, and Parsimony: Dissecting Transcriptional Signatures From Minimal Single-Cell RNA-Seq Output With SALSA by Lozoya, Oswaldo A, McClelland, Kathryn S, Papas, Brian N, Li, Jian-Liang, Yao, Humphrey H-C

“…Single-cell RNA sequencing (scRNA-seq) technologies have precipitated the development of bioinformatic tools to reconstruct cell lineage specification and…”
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Functional Pdgfra fibroblast heterogeneity in normal and fibrotic mouse lung by Trempus, Carol S, Papas, Brian N, Sifre, Maria I, Bortner, Carl D, Scappini, Erica, Tucker, Charles J, Xu, Xin, Johnson, Katina L, Deterding, Leesa J, Williams, Jason G, Johnson, Dylan J, Li, Jian-Liang, Sutton, Deloris, Ganta, Charan, Mahapatra, Debabrata, Arif, Muhammad, Basu, Abhishek, Pommerolle, Lenny, Cinar, Resat, Perl, Anne K, Garantziotis, Stavros

“…Aberrant fibroblast function plays a key role in the pathogenesis of idiopathic pulmonary fibrosis, a devastating disease of unrelenting extracellular matrix…”
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Adsorption of copper on a γ-alumina support by Papas, Brian N., Whitten, Jerry L.

“…The interaction of a Cu atom with two model γ-alumina surfaces was examined using configuration interaction theory. These two surfaces are centered on Td and…”
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Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation by Gambini, Andrés, Stein, Paula, Savy, Virginia, Grow, Edward J., Papas, Brian N., Zhang, Yingpei, Kenan, Anna C., Padilla-Banks, Elizabeth, Cairns, Bradley R., Williams, Carmen J.

“…Embryonic genome activation (EGA) is orchestrated by an intrinsic developmental program initiated during oocyte maturation with translation of stored maternal…”
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Single-cell RNA sequencing reveals a heterogeneous response to Glucocorticoids in breast cancer cells by Hoffman, Jackson A., Papas, Brian N., Trotter, Kevin W., Archer, Trevor K.

“…Steroid hormone receptors such as the Glucocorticoid Receptor (GR) mediate transcriptional responses to hormones and are frequently targeted in the treatment…”
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CI and DFT Studies of the Adsorption of the Nerve Agent Sarin on Surfaces by Papas, Brian N, Petsalakis, Ioannis D, Theodorakopoulos, Giannoula, Whitten, Jerry L

“…A theoretical study is presented on the adsorption of the sarin molecule, a nerve agent, on three model solid surfaces: aliphatic (graphane), aromatic…”
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Dissociation of water on a palladium nanoparticle by Papas, Brian N., Whitten, Jerry L.

“…Ab initio SCF‐CI theory has been used to examine the interactions of a single water molecule with a 31‐atom nanocluster of palladium. Calculations are…”
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Barrier To Linearity and Anharmonic Force Field of the Ketenyl Radical by Simmonett, Andrew C, Stibrich, Nathan J, Papas, Brian N, Schaefer, Henry F, Allen, Wesley D

“…The troublesome barrier to linearity of the ketenyl radical (HCCO) is precisely determined using state-of-the-art computations within the focal point approach,…”
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Concerning the precision of standard density functional programs: Gaussian, Molpro, NWChem, Q-Chem, and Gamess by Papas, Brian N., Schaefer, Henry F.

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Naphthalenyl, Anthracenyl, Tetracenyl, and Pentacenyl Radicals and Their Anions by Papas, Brian N, Wang, Suyun, DeYonker, Nathan J, Woodcock, Henry L, Schaefer, Henry F

“…Electronic structure theory has been applied to the naphthalene-, anthracene-, tetracene-, and pentacene-based radicals and their anions. Five different…”
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Developmental estrogen exposure in mice disrupts uterine epithelial cell differentiation and causes adenocarcinoma via Wnt/[beta]-catenin and PI3K/AKT signaling by Padilla-Banks, Elizabeth, Jefferson, Wendy N, Papas, Brian N, Suen, Alisa A, Xu, Xin, Carreon, Diana V, Willson, Cynthia J, Quist, Erin M, Williams, Carmen J

“…Tissue development entails genetically programmed differentiation of immature cell types to mature, fully differentiated cells. Exposure during development to…”
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Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing by Xiao, Wenming, Ren, Luyao, Chen, Zhong, Fang, Li Tai, Zhao, Yongmei, Lack, Justin, Guan, Meijian, Zhu, Bin, Jaeger, Erich, Kerrigan, Liz, Blomquist, Thomas M., Hung, Tiffany, Sultan, Marc, Idler, Kenneth, Lu, Charles, Scherer, Andreas, Kusko, Rebecca, Moos, Malcolm, Xiao, Chunlin, Sherry, Stephen T., Abaan, Ogan D., Chen, Wanqiu, Chen, Xin, Nordlund, Jessica, Liljedahl, Ulrika, Maestro, Roberta, Polano, Maurizio, Drabek, Jiri, Vojta, Petr, Kõks, Sulev, Reimann, Ene, Madala, Bindu Swapna, Mercer, Timothy, Miller, Chris, Jacob, Howard, Truong, Tiffany, Moshrefi, Ali, Natarajan, Aparna, Granat, Ana, Schroth, Gary P., Kalamegham, Rasika, Peters, Eric, Petitjean, Virginie, Walton, Ashley, Shen, Tsai-Wei, Talsania, Keyur, Vera, Cristobal Juan, Langenbach, Kurt, de Mars, Maryellen, Hipp, Jennifer A., Willey, James C., Wang, Jing, Shetty, Jyoti, Kriga, Yuliya, Raziuddin, Arati, Tran, Bao, Zheng, Yuanting, Yu, Ying, Cam, Margaret, Jailwala, Parthav, Nguyen, Cu, Meerzaman, Daoud, Chen, Qingrong, Yan, Chunhua, Ernest, Ben, Mehra, Urvashi, Jensen, Roderick V., Jones, Wendell, Li, Jian-Liang, Papas, Brian N., Pirooznia, Mehdi, Chen, Yun-Ching, Seifuddin, Fayaz, Li, Zhipan, Liu, Xuelu, Resch, Wolfgang, Wang, Jingya, Wu, Leihong, Yavas, Gokhan, Miles, Corey, Ning, Baitang, Tong, Weida, Mason, Christopher E., Donaldson, Eric, Lababidi, Samir, Staudt, Louis M., Tezak, Zivana, Hong, Huixiao, Wang, Charles, Shi, Leming

“…Clinical applications of precision oncology require accurate tests that can distinguish true cancer-specific mutations from errors introduced at each step of…”
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Essential role of Mg 2+ in mouse preimplantation embryo development revealed by TRPM7 chanzyme-deficient gametes by Gupta, Neha, Soriano-Úbeda, Cristina, Stein, Paula, Savy, Virginia, Papas, Brian N, Ardestani, Goli, Carvacho, Ingrid, Alfandari, Dominique, Williams, Carmen J, Fissore, Rafael A

“…TRPM7 (transient receptor potential cation channel subfamily M member 7) is a chanzyme with channel and kinase domains essential for embryo development. Using…”
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Concerning the precision of standard density functional programs: Gaussian, M olpro, NWC hem, Q-C hem, and G amess by Papas, Brian N., Schaefer, Henry F.

“…The density functionals BLYP and B3LYP in five major quantum chemistry packages have been applied to 83 molecules found in the G2/97 test set. The goal of this…”
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