Search Results - "Papakostas, G I"

Assessment of a multi-assay, serum-based biological diagnostic test for major depressive disorder: a Pilot and Replication Study by Papakostas, G I, Shelton, R C, Kinrys, G, Henry, M E, Bakow, B R, Lipkin, S H, Pi, B, Thurmond, L, Bilello, J A

“…Despite decades of intensive research, the development of a diagnostic test for major depressive disorder (MDD) had proven to be a formidable and elusive task,…”
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A phase 2, double-blind, placebo-controlled study of NSI-189 phosphate, a neurogenic compound, among outpatients with major depressive disorder by Papakostas, G. I., Johe, K., Hand, H., Drouillard, A., Russo, P., Kay, G., Kashambwa, R., Hoeppner, B., Flynn, M., Yeung, A., Martinson, M. A., Fava, M.

“…NSI-189 is a novel neurogenic compound independent of monoamine reuptake pathways. This trial evaluated oral NSI-189 as monotherapy in major depressive…”
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Efficacy of the sequential integration of psychotherapy and pharmacotherapy in major depressive disorder: a preliminary meta-analysis by Guidi, J, Fava, G A, Fava, M, Papakostas, G I

“…Prevention of relapse and recurrence represents an important task in the successful treatment of major depressive disorder (MDD). The aim of this meta-analysis…”
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A meta-analysis of clinical trials comparing mirtazapine with selective serotonin reuptake inhibitors for the treatment of major depressive disorder by Papakostas, GI, Homberger, CH, Fava, M.

“…Over the past few years, a number of studies have suggested that the treatment of major depressive disorder (MDD) with anti-depressants enhancing both…”
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A detailed examination of cytokine abnormalities in Major Depressive Disorder by Simon, N.M, McNamara, K, Chow, C.W, Maser, R.S, Papakostas, G.I, Pollack, M.H, Nierenberg, A.A, Fava, M, Wong, K.K

“…Abstract Recent technological advances offer an opportunity to further elucidate the complex cytokine network in Major Depressive Disorder (MDD). Twenty…”
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Towards new mechanisms: an update on therapeutics for treatment-resistant major depressive disorder by Papakostas, G I, Ionescu, D F

“…Depression is a devastating disorder that places a significant burden on both the individual and society. As such, the discovery of novel therapeutics and…”
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SAMe and sexual functioning by Dording, C.M, Mischoulon, D, Shyu, I, Alpert, J.E, Papakostas, G.I

“…Abstract Background Sexual dysfunction is a known side effect of antidepressant treatment (ADT), affecting up to 58–73% of those who receive ADT, potentially…”
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Effects of S-adenosylmethionine augmentation of serotonin-reuptake inhibitor antidepressants on cognitive symptoms of major depressive disorder by Levkovitz, Y, Alpert, J.E, Brintz, C.E, Mischoulon, D, Papakostas, G.I

“…Abstract Major depressive disorder (MDD) is often accompanied by significant cognitive impairment, and there are limited interventions specific to this…”
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Experimental medication treatment approaches for depression by Ionescu, D F, Papakostas, G I

“…Depression is one of the most common psychiatric conditions. Symptoms can lead to significant disability, which result in impairments in overall quality of…”
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Reduced frontal-subcortical white matter connectivity in association with suicidal ideation in major depressive disorder by Myung, W, Han, C E, Fava, M, Mischoulon, D, Papakostas, G I, Heo, J-Y, Kim, K W, Kim, S T, Kim, D J H, Kim, D K, Seo, S W, Seong, J-K, Jeon, H J

“…Major depressive disorder (MDD) and suicidal behavior have been associated with structural and functional changes in the brain. However, little is known…”
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Continuation cognitive-behavioural therapy maintains attributional style improvement in depressed patients responding acutely to fluoxetine by Petersen, T, Harley, R, Papakostas, G I, Montoya, H D, Fava, M, Alpert, J E

“…Little is known about how continuation and maintenance cognitive-behavioural therapy (CBT) influences important psychological constructs that may be associated…”
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Is S-Adenosyl Methionine (SAMe) for Depression Only Effective in Males? A Re-Analysis of Data from a Randomized Clinical Trial by Sarris, J, Price, L H, Carpenter, L L, Tyrka, A R, Ng, C H, Papakostas, G I, Jaeger, A, Fava, M, Mischoulon, D

“…The aim of this study was to examine whether gender differences may have affected treatment response to S-adenosyl methionine (SAMe) in a recent failed…”
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Pharmacologic and therapeutic strategies in treatment-resistant depression. Switching antidepressants vs. conventional augmentation strategies by Papakostas, G I

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Augmentation of antidepressants for treatment-resistant major depressive disorder in the post-STARD Era: Evidence for newer agents by Papakostas, G I

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Predictors, moderators, and mediators of symptom improvement in major depressive disorder: Overview, definition, and significance by Papakostas, G.I

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Efficacy of Antidepressants for Late-Life Depression: A Meta-Analysis and Meta-Regression of Placebo-Controlled Randomized Trials by TEDESCHINI, Enrico, LEVKOVITZ, Yeciel, LOVIENO, Nadia, AMERAL, Victoria E, CRAIG NELSON, J, PAPAKOSTAS, George L

“…Late-life depression is an important public health issue, given the growing proportion of the elderly relative to the general population in the developed…”
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Treatment-resistant depression and Axis II comorbidity by Petersen, Timothy, Hughes, Megan, Papakostas, George I, Kant, Alexis, Fava, Maurizio, Rosenbaum, Jerrold F, Nierenberg, Andrew A

“…Researchers of unipolar depression have speculated that personality disturbance is a contributing factor in the development of treatment resistance. The…”
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Effects of psychiatric disorders and psychotropic medications on prolactin and bone metabolism by MISRA, Madhusmita, PAPAKOSTAS, George I, KLIBANSKI, Anne

“…Osteoporosis occurs in common psychiatric conditions and causes significant morbidity. Many neuroleptic medications can cause hyperprolactinemia, which can…”
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A cross-sectional study of the prevalence of cognitive and physical symptoms during long-term antidepressant treatment by FAVA, Maurizio, GRAVES, Lesley M, BENAZZI, Franco, SCALIA, Margaret J, IOSIFESCU, Dan V, ALPERT, Jonathan E, PAPAKOSTAS, George I

“…Antidepressant therapies have been associated with a variety of side effects of both physical and psychological nature. Until recently, however, the majority…”
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Resolution of Sleepiness and Fatigue in Major Depressive Disorder: A Comparison of Bupropion and the Selective Serotonin Reuptake Inhibitors by Papakostas, George I., Nutt, David J., Hallett, Lindsay A., Tucker, Vivian L., Krishen, Alok, Fava, Maurizio

“…The purpose of this study was to examine whether the treatment of major depressive disorder (MDD) with the norepinephrine-dopamine reuptake inhibitor (NDRI)…”
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