Search Results - "Papagiouvannis, Georgios"
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Trolox, Ferulic, Sinapic, and Cinnamic Acid Derivatives of Proline and GABA with Antioxidant and/or Anti-Inflammatory Properties
Published in Molecules (Basel, Switzerland) (08-08-2024)“…Degenerative conditions, such as neurodegenerative disorders (Alzheimer's disease (AD), Parkinson's disease (PD)) and cardiovascular diseases, are complex,…”
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Lipoic acid. Kinetics and pluripotent biological properties and derivatives
Published in Molecular biology reports (01-09-2021)“…Lipoic acid (LA) is globally known and its supplements are widely used. Despite its importance for the organism it is not considered a vitamin any more. The…”
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Nipecotic Acid Derivatives as Potent Agents against Neurodegeneration: A Preliminary Study
Published in Molecules (Basel, Switzerland) (01-10-2022)“…Alzheimer’s Disease (AD) is a common neurodegenerative disorder characterized by memory loss and cognitive impairment. Its pathology has not been fully…”
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Ferulic, Sinapic, 3,4-Dimethoxycinnamic Acid and Indomethacin Derivatives with Antioxidant, Anti-Inflammatory and Hypolipidemic Functionality
Published in Antioxidants (01-07-2023)“…A series of thiomorpholine and cinnamyl alcohol derivatives, conjugated with cinnamic acid-containing moieties, such as ferulic acid, sinapic acid and…”
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Enhancement of the Anti-Inflammatory Activity of NSAIDs by Their Conjugation with 3,4,5-Trimethoxybenzyl Alcohol
Published in Molecules (Basel, Switzerland) (24-03-2022)“…The synthesis of derivatives of three nonspecific COX-1 and COX-2 inhibitors, ibuprofen, ketoprofen, naproxen is presented. These acids were connected via an…”
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Active Anti-Inflammatory and Hypolipidemic Derivatives of Lorazepam
Published in Molecules (Basel, Switzerland) (09-09-2019)“…Novel derivatives of some non steroidal anti-inflammatory drugs, as well as of the antioxidants α-lipoic acid, trolox and (…”
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Antioxidant Serine-(NSAID) Hybrids with Anti-Inflammatory and Hypolipidemic Potency
Published in Molecules (Basel, Switzerland) (02-07-2021)“…A series of L-serine amides of antioxidant acids, such as Trolox, (E)-3-(3,5-di-tert-butyl-4-hydroxyphenyl)acrylic acid (phenolic derivative of cinnamic acid)…”
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Multi-Target Directed Compounds with Antioxidant and/or Anti- Inflammatory Properties as Potent Agents for Alzheimer's Disease
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-01-2021)“…Alzheimer's Disease (AD) is one of the most common neurodegenerative disorders, characterized by memory deficits and cognitive impairment. Acetylcholinesterase…”
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Design, synthesis, and pharmacological evaluation of indazole carboxamides of N-substituted pyrrole derivatives as soybean lipoxygenase inhibitors
Published in Molecular diversity (25-12-2023)“…In this paper, we attempted to develop a novel class of compounds against lipoxygenase, a key enzyme in the biosynthesis of leukotrienes implicated in a series…”
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COVID-19 and liver injury: An ongoing challenge
Published in World journal of gastroenterology : WJG (14-01-2023)“…The new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified in December 2019, in Wuhan, China. The virus was rapidly spread…”
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