Search Results - "Papagiannouli, Fani"
-
1
Endocytosis at the Crossroad of Polarity and Signaling Regulation: Learning from Drosophila melanogaster and Beyond
Published in International journal of molecular sciences (23-04-2022)“…Cellular trafficking through the endosomal-lysosomal system is essential for the transport of cargo proteins, receptors and lipids from the plasma membrane…”
Get full text
Journal Article -
2
The HOX-Apoptosis Regulatory Interplay in Development and Disease
Published in Current topics in developmental biology (2015)“…Apoptosis is a cellular suicide program, which is on the one hand used to remove superfluous cells thereby promoting tissue or organ morphogenesis. On the…”
Get full text
Journal Article -
3
The Dlg Module and Clathrin-Mediated Endocytosis Regulate EGFR Signaling and Cyst Cell-Germline Coordination in the Drosophila Testis
Published in Stem cell reports (14-05-2019)“…Tissue homeostasis and repair relies on proper communication of stem cells and their differentiating daughters with the local tissue microenvironment. In the…”
Get full text
Journal Article -
4
Decoding the Regulatory Logic of the Drosophila Male Stem Cell System
Published in Cell reports (Cambridge) (11-09-2018)“…The niche critically controls stem cell behavior, but its regulatory input at the whole-genome level is poorly understood. We elucidated transcriptional…”
Get full text
Journal Article -
5
Antagonistic regulation of apoptosis and differentiation by the Cut transcription factor represents a tumor-suppressing mechanism in Drosophila
Published in PLoS genetics (01-03-2012)“…Apoptosis is essential to prevent oncogenic transformation by triggering self-destruction of harmful cells, including those unable to differentiate. However,…”
Get full text
Journal Article -
6
Stage-specific control of stem cell niche architecture in the Drosophila testis by the posterior Hox gene Abd-B
Published in Computational and structural biotechnology journal (01-01-2015)“…A fundamental question in biology is how complex structures are maintained after their initial specification. We address this question by reviewing the role of…”
Get full text
Journal Article -
7
discs large in the Drosophila testis: an old player on a new task
Published in Fly (Austin, Tex.) (01-10-2010)“…Gamete development requires a coordinated soma-germ line interaction that ensures renewal and differentiation of germline and somatic stem cells. The physical…”
Get full text
Journal Article -
8
The internal structure of embryonic gonads and testis development in Drosophila melanogaster requires scrib, lgl and dlg activity in the soma
Published in The International journal of developmental biology (2013)“…Interest in the mechanism leading to the formation of the germline and its differentiation during Drosophila development, initiated even as soon as the first…”
Get full text
Journal Article -
9
The Hox Gene Abd-B Controls Stem Cell Niche Function in the Drosophila Testis
Published in Developmental cell (27-01-2014)“…Proper niche architecture is critical for stem cell function, yet only few upstream regulators are known. Here, we report that the Hox transcription factor…”
Get full text
Journal Article -
10
Shaping the niche: Lessons from the Drosophila testis and other model systems
Published in Biotechnology journal (01-06-2012)“…Stem cells are fascinating, as they supply the cells that construct our adult bodies and replenish, as we age, worn out, damaged, and diseased tissues. Stem…”
Get full text
Journal Article -
11
The Hox Gene Abd-B Controls Stem Cell Niche Function in the Drosophila Testis
Published in Developmental cell (24-02-2014)Get full text
Journal Article -
12
discs large regulates somatic cyst cell survival and expansion in Drosophila testis
Published in Cell research (01-10-2009)“…Gonad development requires a coordinated soma-germline interaction that ensures renewal and differentiation of germline and somatic stem cells to ultimately…”
Get full text
Journal Article -
13
The cis-regulatory code of Hox function in Drosophila
Published in The EMBO journal (01-08-2012)“…Precise gene expression is a fundamental aspect of organismal function and depends on the combinatorial interplay of transcription factors (TFs) with cis…”
Get full text
Journal Article -
14
Erratum To: The cis‐regulatory code of Hox function in Drosophila
Published in The EMBO journal (12-11-2015)“…Graphical Abstract…”
Get full text
Journal Article -
15
The cis-regulatory code of Hox function in Drosophila
Published in The EMBO journal (12-11-2015)Get full text
Journal Article -
16
Developmental Control of Nuclear Size and Shape by kugelkern and kurzkern
Published in Current biology (21-03-2006)“…The shape of a nucleus depends on the nuclear lamina, which is tightly associated with the inner nuclear membrane and on the interaction with the cytoskeleton…”
Get full text
Journal Article -
17
Stage-specific control of niche positioning and integrity in the Drosophila testis
Published in Mechanisms of development (01-11-2015)“…A fundamental question is how complex structures are maintained after their initial specification. Stem cells reside in a specialized microenvironment, called…”
Get full text
Journal Article -
18
Requirements for scribble expression in newly formed gonads of Drosophila embryos
Published in Gene Expression Patterns (01-05-2003)“…The tumour suppressor gene scribble ( scrib) is required for epithelial polarity and growth control in Drosophila, and encodes two protein isoforms. Here, we…”
Get full text
Journal Article