Search Results - "Papageorgiou, Sokratis G."
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Current and Future Treatments in Alzheimer Disease: An Update
Published in Journal of Central Nervous System Disease (2020)“…Disease-modifying treatment strategies for Alzheimer disease (AD) are still under extensive research. Nowadays, only symptomatic treatments exist for this…”
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Current and future treatments for Alzheimer’s disease
Published in Therapeutic Advances in Neurological Disorders (01-01-2013)“…Alzheimer’s dementia (AD) is increasingly being recognized as one of the most important medical and social problems in older people in industrialized and…”
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A Novel SNCA A30G Mutation Causes Familial Parkinsonʼs Disease
Published in Movement disorders (01-07-2021)“…ABSTRACT Background The SNCA gene encoding α‐synuclein (αSyn) is the first gene identified to cause autosomal‐dominant Parkinsonʼs disease (PD). Objective We…”
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Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau
Published in Science (American Association for the Advancement of Science) (20-11-2020)“…Neurodegeneration in Alzheimer's disease (AD) is closely associated with the accumulation of pathologic tau aggregates in the form of neurofibrillary tangles…”
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Exploring the Genetic Landscape of Mild Behavioral Impairment as an Early Marker of Cognitive Decline: An Updated Review Focusing on Alzheimer's Disease
Published in International journal of molecular sciences (24-02-2024)“…The clinical features and pathophysiology of neuropsychiatric symptoms (NPSs) in dementia have been extensively studied. However, the genetic architecture and…”
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Environmental Impact on the Epigenetic Mechanisms Underlying Parkinson's Disease Pathogenesis: A Narrative Review
Published in Brain sciences (28-01-2022)“…Parkinson's disease (PD) is the second most common neurodegenerative disorder with an unclear etiology and no disease-modifying treatment to date. PD is…”
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Genetic Insights into the Molecular Pathophysiology of Depression in Parkinson's Disease
Published in Medicina (Kaunas, Lithuania) (01-06-2023)“…: Parkinson's disease (PD) is a clinically heterogeneous disorder with poorly understood pathological contributing factors. Depression presents one of the most…”
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Physical Training In-Game Metrics for Cognitive Assessment: Evidence from Extended Trials with the Fitforall Exergaming Platform
Published in Sensors (Basel, Switzerland) (26-08-2021)“…Conventional clinical cognitive assessment has its limitations, as evidenced by the environmental shortcomings of various neuropsychological tests conducted…”
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Structural and functional impairment of the retina and optic nerve in Alzheimer's disease
Published in Current Alzheimer research (01-09-2012)“…The purpose of this study was to evaluate the macular and retinal nerve fiber layer (RNFL) thickness, and the electrical activity of the macula in patients…”
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Elucidating the Beneficial Effects of Ginger (Zingiber officinale Roscoe) in Parkinson’s Disease
Published in ACS pharmacology & translational science (14-10-2022)“…Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease (AD), and its pathogenesis remains obscure. Current…”
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Driving and Alzheimer’s dementia or mild cognitive impairment: a systematic review of the existing guidelines emphasizing on the neurologist’s role
Published in Neurological sciences (01-12-2021)“…Background Driving is a complex task requiring the integrity and the cooperation of cognition, motor, and somatosensory skills, all of which are impacted by…”
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Unraveling the Potential Underlying Mechanisms of Mild Behavioral Impairment: Focusing on Amyloid and Tau Pathology
Published in Cells (Basel, Switzerland) (08-07-2024)“…The emergence of sustained neuropsychiatric symptoms (NPS) among non-demented individuals in later life, defined as mild behavioral impairment (MBI), is linked…”
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The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group
Published in Alzheimer's research & therapy (17-04-2017)“…Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the…”
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Multimodal Approach to Neurocognitive Function in People Living with HIV in the cART Era: A Comprehensive Review
Published in Life (Basel, Switzerland) (01-04-2024)“…Combination antiretroviral treatment (cART) has revolutionized the management of human immunodeficiency virus (HIV) and has markedly improved the disease…”
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Exploring the Role of ACE2 as a Connecting Link between COVID-19 and Parkinson's Disease
Published in Life (Basel, Switzerland) (01-02-2023)“…Coronavirus disease 2019 (COVID-19) is frequently accompanied by neurological manifestations such as headache, delirium, and epileptic seizures, whereas…”
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Neurological Examination via Telemedicine: An Updated Review Focusing on Movement Disorders
Published in Medicina (Kaunas, Lithuania) (01-06-2024)“…Patients with movement disorders such as Parkinson's disease (PD) living in remote and underserved areas often have limited access to specialized healthcare,…”
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Imaging Markers for Normal Pressure Hydrocephalus: An Overview
Published in Biomedicines (24-04-2023)“…Idiopathic bormal pressure hydrocephalus (iNPH) is a neurological syndrome that clinically presents with Hakim's triad, namely cognitive impairment, gait…”
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Rhythmic cueing, dance, resistance training, and Parkinson's disease: A systematic review and meta-analysis
Published in Frontiers in neurology (09-08-2022)“…Objectives The aim of the present systematic review and meta-analysis was to synthesize evidence associated with the functional and clinical effectiveness of…”
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Pharmacological and Non-Pharmacological Treatments for Depression in Parkinson’s Disease: An Updated Review
Published in Medicina (Kaunas, Lithuania) (01-08-2023)“…Depression represents one of the most common non-motor disorders in Parkinson’s disease (PD) and it has been related to worse life quality, higher levels of…”
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The effects of a computer-based cognitive and physical training program in a healthy and mildly cognitive impaired aging sample
Published in Aging & mental health (03-10-2014)“…Objectives: The Long Lasting Memories (LLM) program concerns a newly integrated platform which combines cognitive exercises with physical activity within the…”
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