Search Results - "Papageorgiou, Sokratis"
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Current and Future Treatments in Alzheimer Disease: An Update
Published in Journal of Central Nervous System Disease (2020)“…Disease-modifying treatment strategies for Alzheimer disease (AD) are still under extensive research. Nowadays, only symptomatic treatments exist for this…”
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Current and future treatments for Alzheimer’s disease
Published in Therapeutic Advances in Neurological Disorders (01-01-2013)“…Alzheimer’s dementia (AD) is increasingly being recognized as one of the most important medical and social problems in older people in industrialized and…”
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Book Review Journal Article -
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APOE Genotype and Alzheimer’s Disease: The Influence of Lifestyle and Environmental Factors
Published in ACS chemical neuroscience (04-08-2021)“…Alzheimer’s disease (AD) is the most common neurodegenerative disorder with obscure pathogenesis and no disease-modifying therapy to date. AD is multifactorial…”
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A Novel SNCA A30G Mutation Causes Familial Parkinsonʼs Disease
Published in Movement disorders (01-07-2021)“…ABSTRACT Background The SNCA gene encoding α‐synuclein (αSyn) is the first gene identified to cause autosomal‐dominant Parkinsonʼs disease (PD). Objective We…”
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Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau
Published in Science (American Association for the Advancement of Science) (20-11-2020)“…Neurodegeneration in Alzheimer's disease (AD) is closely associated with the accumulation of pathologic tau aggregates in the form of neurofibrillary tangles…”
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The impact of COVID‐19 pandemic on people with mild cognitive impairment/dementia and on their caregivers
Published in International journal of geriatric psychiatry (01-04-2021)“…Background The novel coronavirus disease (COVID‐19) was first detected in Mainland China in December 2019, and soon it spread throughout the world, with…”
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Emerging Therapeutic Potential of Fluoxetine on Cognitive Decline in Alzheimer's Disease: Systematic Review
Published in International journal of molecular sciences (13-06-2024)“…Fluoxetine, a commonly prescribed medication for depression, has been studied in Alzheimer's disease (AD) patients for its effectiveness on cognitive symptoms…”
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Exploring the Genetic Landscape of Mild Behavioral Impairment as an Early Marker of Cognitive Decline: An Updated Review Focusing on Alzheimer's Disease
Published in International journal of molecular sciences (24-02-2024)“…The clinical features and pathophysiology of neuropsychiatric symptoms (NPSs) in dementia have been extensively studied. However, the genetic architecture and…”
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Genetic Insights into the Molecular Pathophysiology of Depression in Parkinson's Disease
Published in Medicina (Kaunas, Lithuania) (01-06-2023)“…: Parkinson's disease (PD) is a clinically heterogeneous disorder with poorly understood pathological contributing factors. Depression presents one of the most…”
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Environmental Impact on the Epigenetic Mechanisms Underlying Parkinson's Disease Pathogenesis: A Narrative Review
Published in Brain sciences (28-01-2022)“…Parkinson's disease (PD) is the second most common neurodegenerative disorder with an unclear etiology and no disease-modifying treatment to date. PD is…”
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Episodic Memory in Alzheimer Disease, Frontotemporal Dementia, and Dementia With Lewy Bodies/Parkinson Disease Dementia: Disentangling Retrieval From Consolidation
Published in Alzheimer disease and associated disorders (01-01-2016)“…Differences in episodic memory performance in patients with Alzheimer disease (AD), frontotemporal dementia (FTD), dementia with Lewy bodies (DLB)/Parkinson…”
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The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group
Published in Alzheimer's research & therapy (17-04-2017)“…Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the…”
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A case of corticobasal syndrome possibly associated with anti-Yo antibodies
Published in Current medical research and opinion (02-10-2024)“…Corticobasal syndrome (CBS) is a rare form of atypical parkinsonism, most commonly caused by neurodegenerative disorders. Autoimmune underlying conditions are…”
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Predictors of accidents in people with mild cognitive impairment, mild dementia due to Alzheimer's disease and healthy controls in simulated driving
Published in International journal of geriatric psychiatry (01-08-2020)“…Summary Objectives To examine the driving variables that predict accident probability in mild dementia due to Alzheimer's disease (AD), mild cognitive…”
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Structural and functional impairment of the retina and optic nerve in Alzheimer's disease
Published in Current Alzheimer research (01-09-2012)“…The purpose of this study was to evaluate the macular and retinal nerve fiber layer (RNFL) thickness, and the electrical activity of the macula in patients…”
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Psychosis in Parkinson’s Disease: A Lesson from Genetics
Published in Genes (20-06-2022)“…Psychosis in Parkinson’s disease (PDP) represents a common and debilitating condition that complicates Parkinson’s disease (PD), mainly in the later stages…”
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Physical Training In-Game Metrics for Cognitive Assessment: Evidence from Extended Trials with the Fitforall Exergaming Platform
Published in Sensors (Basel, Switzerland) (26-08-2021)“…Conventional clinical cognitive assessment has its limitations, as evidenced by the environmental shortcomings of various neuropsychological tests conducted…”
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The nonverbal BriefScreen: A cognitive screening method for patients with limited language and motor abilities
Published in Applied neuropsychology. Adult (04-03-2023)“…Dementia and significant cognitive decline are frequent sequelae of stroke, but are difficult to evaluate when aphasia and/or motor impairment are present. The…”
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Motor and Nonmotor Features of Carriers of the p.A53T Alpha-Synuclein Mutation: A Longitudinal Study
Published in Movement disorders (01-08-2016)“…ABSTRACT Background G209A SNCA mutation carriers represent an important group of genetic PD. We describe motor and nonmotor features of G209A SNCA mutation…”
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Elucidating the Beneficial Effects of Ginger (Zingiber officinale Roscoe) in Parkinson’s Disease
Published in ACS pharmacology & translational science (14-10-2022)“…Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease (AD), and its pathogenesis remains obscure. Current…”
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