Search Results - "Papadopoulos, Panayiota"

Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease by Zhang, Luqing, Papadopoulos, Panayiota, Hamel, Edith

“…Background and Purpose Transient receptor potential vanilloid type 4 (TRPV4) channels are expressed in brain endothelial cells, but their role in regulating…”
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Pioglitazone improves reversal learning and exerts mixed cerebrovascular effects in a mouse model of Alzheimer's disease with combined amyloid-β and cerebrovascular pathology by Papadopoulos, Panayiota, Rosa-Neto, Pedro, Rochford, Joseph, Hamel, Edith

“…Animal models of Alzheimer's disease (AD) are invaluable in dissecting the pathogenic mechanisms and assessing the efficacy of potential new therapies. Here,…”
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Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer’s disease model by Ongali, Brice, Nicolakakis, Nektaria, Tong, Xin-Kang, Aboulkassim, Tahar, Papadopoulos, Panayiota, Rosa-Neto, Pedro, Lecrux, Clotilde, Imboden, Hans, Hamel, Edith

“…Abstract Angiotensin II (AngII) receptor blockers that bind selectively AngII type 1 (AT1) receptors may protect from Alzheimer’s disease (AD). We studied the…”
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Brain endothelial TAK1 and NEMO safeguard the neurovascular unit by Ridder, Dirk A, Wenzel, Jan, Müller, Kristin, Töllner, Kathrin, Tong, Xin-Kang, Assmann, Julian C, Stroobants, Stijn, Weber, Tobias, Niturad, Cristina, Fischer, Lisanne, Lembrich, Beate, Wolburg, Hartwig, Grand'Maison, Marilyn, Papadopoulos, Panayiota, Korpos, Eva, Truchetet, Francois, Rades, Dirk, Sorokin, Lydia M, Schmidt-Supprian, Marc, Bedell, Barry J, Pasparakis, Manolis, Balschun, Detlef, D'Hooge, Rudi, Löscher, Wolfgang, Hamel, Edith, Schwaninger, Markus

“…Inactivating mutations of the NF-κB essential modulator (NEMO), a key component of NF-κB signaling, cause the genetic disease incontinentia pigmenti (IP). This…”
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Selective benefits of simvastatin in bitransgenic APPSwe,Ind /TGF-β1 mice by Papadopoulos, Panayiota, Tong, Xin-Kang, Hamel, Edith

“…Abstract Cognitive and cerebrovascular deficits are 2 landmarks of Alzheimer's disease (AD) to target for effective therapy. Here, we evaluated the efficacy of…”
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Transgenic Mice Overexpressing APP and Transforming Growth Factor-β1 Feature Cognitive and Vascular Hallmarks of Alzheimer's Disease by Ongali, Brice, Nicolakakis, Nektaria, Lecrux, Clotilde, Aboulkassim, Tahar, Rosa-Neto, Pedro, Papadopoulos, Panayiota, Tong, Xin-Kang, Hamel, Edith

“…High brain levels of amyloid-β (Aβ) and transforming growth factor-β1 (TGF-β1) have been implicated in the cognitive and cerebrovascular alterations of…”
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Losartan improves cerebrovascular function in a mouse model of Alzheimer's disease with combined overproduction of amyloid-β and transforming growth factor-β1 by Papadopoulos, Panayiota, Tong, Xin-Kang, Imboden, Hans, Hamel, Edith

“…Alterations of the renin-angiotensin system have been implicated in the pathogenesis of Alzheimer's disease. We tested the efficacy of losartan (10 mg/kg/day…”
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Triple inhaled therapy for asthma in Canada by Chapman, Kenneth R., Balter, Meyer, Bhinder, Sacha, Kaplan, Alan, McIvor, Andrew, Papadopoulos, Panayiota, Godbout, Krystelle

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Selective benefits of simvastatin in bitransgenic APPSwe,Ind/TGF- beta 1 mice by Papadopoulos, Panayiota, Tong, Xin-Kang, Hamel, Edith

“…Cognitive and cerebrovascular deficits are 2 landmarks of Alzheimer's disease (AD) to target for effective therapy. Here, we evaluated the efficacy of…”
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Endothelial TRPV 4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to A lzheimer's disease by Zhang, Luqing, Papadopoulos, Panayiota, Hamel, Edith

“…Background and Purpose Transient receptor potential vanilloid type 4 ( TRPV 4) channels are expressed in brain endothelial cells, but their role in regulating…”
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Urotensin-II and cardiovascular remodeling by Papadopoulos, Panayiota, Bousette, Nicolas, Giaid, Adel

“…Urotensin-II (U-II), a cyclic undecapeptide, and its receptor, UT, have been linked to vascular and cardiac remodeling. In patients with coronary artery…”
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Brain endothelial TAK1 and NEMO safeguard the neurovascular unit by Ridder, Dirk A., Wenzel, Jan, Müller, Kristin, Töllner, Kathrin, Tong, Xin-Kang, Assmann, Julian Christopher, Stroobants, Stijn, Weber, Tobias, Niturad, Cristina Elena, Fischer, Lisanne, Lembrich, Beate, Wolburg, Hartwig, Grand'Maison, Marilyn, Papadopoulos, Panayiota, Korpos, Eva, Truchetet, Francois, Rades, Dirk, Sorokin, Lydia, Schmidt-Supprian, Marc, Bedell, Barry, Pasparakis, Manolis, Balschun, Detlef, D'Hooge, Rudi, Löscher, Wolfgang, Hamel, Edith, Schwaninger, Markus

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Urotensin-II and cardiovascular remodeling: Urotensin II, urotensin II-related peptide and their receptors by PAPADOPOULOS, Panayiota, BOUSETTE, Nicolas, GIAID, Adel

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Targeted overexpression of the human urotensin receptor transgene in smooth muscle cells: Effect of UT antagonism in ApoE knockout mice fed with Western diet by Papadopoulos, Panayiota, Bousette, Nicolas, Al-Ramli, Wisam, You, Zhipeng, Behm, David J, Ohlstein, Eliot H, Harrison, Stephen M, Douglas, Stephen A, Giaid, Adel

“…Abstract Urotensin II (UII) and its receptor UT are upregulated in the pathological setting of various cardiovascular diseases including atherosclerosis…”
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Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimers Disease with Combined Amyloid- beta and Cerebrovascular Pathology. e68612 by Papadopoulos, Panayiota, Rosa-Neto, Pedro, Rochford, Joseph, Hamel, Edith

“…Animal models of Alzheimer's disease (AD) are invaluable in dissecting the pathogenic mechanisms and assessing the efficacy of potential new therapies. Here,…”
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Selective in vivo antagonism of endothelin receptors in transforming growth factor-beta1 transgenic mice that mimic the vascular pathology of Alzheimer's disease by Papadopoulos, Panayiota, Ongali, Brice, Hamel, Edith

“…Increased levels of transforming growth factor-beta1 (TGF-beta1) induce a vascular pathology that shares similarities with that seen in Alzheimer's disease,…”
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Augmented aortic atherosclerosis in ApoE deficient mice with targeted overexpression of urotensin-II receptor by Papadopoulos, Panayiota

“…Urotensin-II (U-II) and its receptor UT are upregulated in the pathological setting of various cardiovascular diseases including atherosclerosis. However,…”
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Transgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's disease by Ongali, Brice, Nicolakakis, Nektaria, Lecrux, Clotilde, Aboulkassim, Tahar, Rosa-Neto, Pedro, Papadopoulos, Panayiota, Tong, Xin-Kang, Hamel, Edith

“…High brain levels of amyloid-β (Aβ) and transforming growth factor-β1 (TGF-β1) have been implicated in the cognitive and cerebrovascular alterations of…”
Get full text