Search Results - "Papaconstantinou, Matthew"
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Thrombin Functions through Its RGD Sequence in a Non-canonical Conformation
Published in The Journal of biological chemistry (19-08-2005)“…Previous studies have suggested that thrombin interacts with integrins in endothelial cells through its RGD (Arg-187, Gly-188, Asp-189) sequence. All existing…”
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Thrombin mediates mitogenesis and survival of human endothelial cells through distinct mechanisms
Published in American Journal of Physiology: Cell Physiology (01-05-2008)“…Thrombin has been reported to play a pivotal role in the initiation of angiogenesis by indirectly regulating and organizing a network of angiogenic molecules…”
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On the mode of action of thrombin-induced angiogenesis: thrombin peptide, TP508, mediates effects in endothelial cells via alphavbeta3 integrin
Published in Thrombosis and haemostasis (01-10-2004)“…In a previous report we have presented evidence that thrombin interacts with alpha(v)beta(3) integrin in endothelial cells at the molecular and cellular level…”
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