Search Results - "Paone, Stephanie"

Endothelial cell apoptosis and the role of endothelial cell-derived extracellular vesicles in the progression of atherosclerosis by Paone, Stephanie, Baxter, Amy A., Hulett, Mark D., Poon, Ivan K. H.

“…To maintain physiological homeostasis, cell turnover occurs every day in the body via a form of programmed cell death called apoptosis. During apoptosis, cells…”
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A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure by Atkin-Smith, Georgia K., Tixeira, Rochelle, Paone, Stephanie, Mathivanan, Suresh, Collins, Christine, Liem, Michael, Goodall, Katharine J., Ravichandran, Kodi S., Hulett, Mark D., Poon, Ivan K.H.

“…Disassembly of apoptotic cells into smaller fragments (a form of extracellular vesicle called apoptotic bodies) can facilitate removal of apoptotic debris and…”
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Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles in vitro by Poon, Ivan K. H., Parkes, Michael A. F., Jiang, Lanzhou, Atkin-Smith, Georgia K., Tixeira, Rochelle, Gregory, Christopher D., Ozkocak, Dilara C., Rutter, Stephanie F., Caruso, Sarah, Santavanond, Jascinta P., Paone, Stephanie, Shi, Bo, Hodge, Amy L., Hulett, Mark D., Chow, Jenny D. Y., Phan, Thanh Kha, Baxter, Amy A.

“…Apoptosis is a form of programmed cell death that occurs throughout life as part of normal development as well as pathologic processes including chronic…”
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Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly by Atkin-Smith, Georgia K., Miles, Mark A., Tixeira, Rochelle, Lay, Fung T., Duan, Mubing, Hawkins, Christine J., Phan, Thanh Kha, Paone, Stephanie, Mathivanan, Suresh, Hulett, Mark D., Chen, Weisan, Poon, Ivan K.H.

“…Billions of cells undergo apoptosis daily and often fragment into small, membrane-bound extracellular vesicles termed apoptotic bodies (ApoBDs). We demonstrate…”
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Heparanase: A Novel Therapeutic Target for the Treatment of Atherosclerosis by Nguyen, Tien K, Paone, Stephanie, Chan, Enoch, Poon, Ivan K H, Baxter, Amy A, Thomas, Shane R, Hulett, Mark D

“…Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, and its management places a huge burden on healthcare systems through…”
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Determining the contents and cell origins of apoptotic bodies by flow cytometry by Jiang, Lanzhou, Paone, Stephanie, Caruso, Sarah, Atkin-Smith, Georgia K., Phan, Thanh Kha, Hulett, Mark D., Poon, Ivan K. H.

“…Over 200 billion cells undergo apoptosis every day in the human body in order to maintain tissue homeostasis. Increased apoptosis can also occur under…”
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Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry by Jiang, Lanzhou, Tixeira, Rochelle, Caruso, Sarah, Atkin-Smith, Georgia K, Baxter, Amy A, Paone, Stephanie, Hulett, Mark D, Poon, Ivan K H

“…Annexin A5 and TO-PRO-3 (a nucleic acid–binding dye that stains early apoptotic and necrotic cells differentially) are used to distinguish six types of…”
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Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting by Atkin-Smith, Georgia K., Paone, Stephanie, Zanker, Damien J., Duan, Mubing, Phan, Than K., Chen, Weisan, Hulett, Mark D., Poon, Ivan K. H.

“…Apoptotic bodies (ApoBDs) are membrane-bound extracellular vesicles that can mediate intercellular communication in physiological and pathological settings. By…”
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Heparanase promotes the onset and progression of atherosclerosis in apolipoprotein E gene knockout mice by Nguyen, Tien K., Paone, Stephanie, Baxter, Amy A., Mayfosh, Alyce J., Phan, Thanh Kha, Chan, Enoch, Peter, Karlheinz, Poon, Ivan K.H., Thomas, Shane R., Hulett, Mark D.

“…Atherosclerosis is the primary underlying cause of myocardial infarction and stroke, which are the major causes of death globally. Heparanase (Hpse) is a…”
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Defining the morphologic features and products of cell disassembly during apoptosis by Tixeira, Rochelle, Caruso, Sarah, Paone, Stephanie, Baxter, Amy A., Atkin-Smith, Georgia K., Hulett, Mark D., Poon, Ivan K. H.

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Monocyte apoptotic bodies are vehicles for influenza A virus propagation by Atkin-Smith, Georgia K., Duan, Mubing, Zanker, Damien J., Loh, Liyen, Nguyen, Thi H. O., Koutsakos, Marios, Nguyen, Tien, Jiang, Xiangrui, Carrera, Julio, Phan, Thanh Kha, Liu, Chuanxin, Paone, Stephanie, Oveissi, Sara, Hodge, Amy L., Baxter, Amy A., Kedzierska, Katherine, Mackenzie, Jason M., Hulett, Mark D., Bilsel, Pamuk, Chen, Weisan, Poon, Ivan K. H.

“…The disassembly of apoptotic cells into small membrane-bound vesicles termed apoptotic bodies (ApoBDs) is a hallmark of apoptosis; however, the functional…”
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