Search Results - "Paoloni, Francesca"

Safety and Efficacy of Intensive Insulin Therapy in Critical Neurosurgical Patients by BILOTTA, Federico, CARAMIA, Remo, PAOLONI, Francesca P, DELFINI, Roberto, ROSA, Giovanni

“…Intensive insulin therapy to maintain blood glucose at or below 6.11 mM reduces morbidity and mortality after cardiac surgery and morbidity in medical…”
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AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance by Avvisati, Giuseppe, Lo-Coco, Francesco, Paoloni, Francesca Paola, Petti, Maria Concetta, Diverio, Daniela, Vignetti, Marco, Latagliata, Roberto, Specchia, Giorgina, Baccarani, Michele, Di Bona, Eros, Fioritoni, Giuseppe, Marmont, Filippo, Rambaldi, Alessandro, Di Raimondo, Francesco, Kropp, Maria Grazia, Pizzolo, Giovanni, Pogliani, Enrico M., Rossi, Giuseppe, Cantore, Nicola, Nobile, Francesco, Gabbas, Attilio, Ferrara, Felicetto, Fazi, Paola, Amadori, Sergio, Mandelli, Franco

“…All-trans-retinoic acid (ATRA) has greatly modified the prognosis of acute promyelocytic leukemia; however, the role of maintenance in patients in molecular…”
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IKZF1 (Ikaros) Deletions in BCR-ABL1–Positive Acute Lymphoblastic Leukemia Are Associated With Short Disease-Free Survival and High Rate of Cumulative Incidence of Relapse: A GIMEMA AL WP Report by MARTINELLI, Giovanni, IACOBUCCI, Ilaria, PAPAYANNIDIS, Cristina, PAOLINI, Stefania, ELIA, Loredana, FAZI, Paola, MELONI, Giovanna, AMADORI, Sergio, SAGLIO, Giuseppe, PANE, Fabrizio, BACCARANI, Michele, FOA, Robin, TIZIAVA STORLAZZI, Clelia, VIGNETTI, Marco, PAOLONI, Francesca, CILLONI, Daniela, SOVERINI, Simona, VITALE, Antonella, CHIARETTI, Sabina, CIMINO, Giuseppe

“…The causes of the aggressive nature of BCR-ABL1-positive adult acute lymphoblastic leukemia (ALL) are unknown. To identify, at the submicroscopic level,…”
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Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia by Flex, Elisabetta, Petrangeli, Valentina, Stella, Lorenzo, Chiaretti, Sabina, Hornakova, Tekla, Knoops, Laurent, Ariola, Cristina, Fodale, Valentina, Clappier, Emmanuelle, Paoloni, Francesca, Martinelli, Simone, Fragale, Alessandra, Sanchez, Massimo, Tavolaro, Simona, Messina, Monica, Cazzaniga, Giovanni, Camera, Andrea, Pizzolo, Giovanni, Tornesello, Assunta, Vignetti, Marco, Battistini, Angela, Cavé, Hélène, Gelb, Bruce D, Renauld, Jean-Christophe, Biondi, Andrea, Constantinescu, Stefan N, Foà, Robin, Tartaglia, Marco

“…Aberrant signal transduction contributes substantially to leukemogenesis. The Janus kinase 1 (JAK1) gene encodes a cytoplasmic tyrosine kinase that…”
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IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia by Iacobucci, Ilaria, Iraci, Nunzio, Messina, Monica, Lonetti, Annalisa, Chiaretti, Sabina, Valli, Emanuele, Ferrari, Anna, Papayannidis, Cristina, Paoloni, Francesca, Vitale, Antonella, Storlazzi, Clelia Tiziana, Ottaviani, Emanuela, Guadagnuolo, Viviana, Durante, Sandra, Vignetti, Marco, Soverini, Simona, Pane, Fabrizio, Foà, Robin, Baccarani, Michele, Müschen, Markus, Perini, Giovanni, Martinelli, Giovanni

“…Deletions of IKAROS (IKZF1) frequently occur in B-cell precursor acute lymphoblastic leukemia (B-ALL) but the mechanisms by which they influence pathogenesis…”
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ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression by GUARINI, Anna, MARINELLI, Marilisa, NANNI, Mauro, DEL GIUDICE, Ilaria, ROMANA MAURO, Francesca, TORRENTE, Isabella, FOA, Robin, TAVOLARO, Simona, BELLACCHIO, Emanuele, MAGLIOZZI, Monia, CHIARETTI, Sabina, DE PROPRIS, Maria Stefania, PERAGINE, Nadia, SANTANGELO, Simona, PAOLONI, Francesca

“…The genetic characterization of chronic lymphocytic leukemia cells correlates with the behavior, progression and response to treatment of the disease. Our aim…”
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RNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications by Gianfelici, Valentina, Chiaretti, Sabina, Demeyer, Sofie, Di Giacomo, Filomena, Messina, Monica, La Starza, Roberta, Peragine, Nadia, Paoloni, Francesca, Geerdens, Ellen, Pierini, Valentina, Elia, Loredana, Mancini, Marco, De Propris, Maria Stefania, Apicella, Valerio, Gaidano, Gianluca, Testi, Anna Maria, Vitale, Antonella, Vignetti, Marco, Mecucci, Cristina, Guarini, Anna, Cools, Jan, Foà, Robin

“…Despite therapeutic improvements, a sizable number of patients with T-cell acute lymphoblastic leukemia still have a poor outcome. To unravel the genomic…”
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TP53 mutations are frequent in adult acute lymphoblastic leukemia cases negative for recurrent fusion genes and correlate with poor response to induction therapy by Chiaretti, Sabina, Brugnoletti, Fulvia, Tavolaro, Simona, Bonina, Silvia, Paoloni, Francesca, Marinelli, Marilisa, Patten, Nancy, Bonifacio, Massimiliano, Kropp, Maria Grazia, Sica, Simona, Guarini, Anna, Foà, Robin

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Early postoperative cognitive dysfunction and postoperative delirium after anaesthesia with various hypnotics: study protocol for a randomised controlled trial--the PINOCCHIO trial by Bilotta, Federico, Doronzio, Andrea, Stazi, Elisabetta, Titi, Luca, Zeppa, Ivan Orlando, Cianchi, Antonella, Rosa, Giovanni, Paoloni, Francesca Paola, Bergese, Sergio, Asouhidou, Irene, Ioannou, Polimnia, Abramowicz, Apolonia Elisabeth, Spinelli, Allison, Delphin, Ellise, Ayrian, Eugenia, Zelman, Vladimir, Lumb, Philip

“…Postoperative delirium can result in increased postoperative morbidity and mortality, major demand for postoperative care and higher hospital costs. Hypnotics…”
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P523: THE COMPARISON OF VFLAI, FLAI AND 3 + 7 REGIMENS BY MULTILEVEL PROPENSITY SCORE WEIGHTING HIGHLIGHTS THE BENEFIT OF THE ADDITION OF VENETOCLAX IN NO LOW‐RISK AML TREATED IN GIMEMA TRIALS AND REAL WORLD by Piciocchi, Alfonso, Marconi, Giovanni, Cipriani, Marta, Messina, Monica, Guolo, Fabio, Minetto, Paola, Paoloni, Francesca, Cotugno, Francesca, DI Donato, Laura, Simonetti, Giorgia, Palmieri, Raffaele, Buccisano, Francesco, Fazi, Paola, Vignetti, Marco, M. Lemoni, Roberto, Venditti, Adriano, Martinelli, Giovanni

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P553: PRELIMINARY RESULTS OF MRD ANALYSIS OF AML1718, A PHASE 2 OPEN‐LABEL STUDY OF VENETOCLAX, FLUDARABINE, IDARUBICIN AND CYTARABINE (V‐FLAI) IN THE INDUCTION THERAPY OF NON LOW‐RISK AML by Minetto, Paola, Guolo, Fabio, Rosellini, Sara, Piciocchi, Alfonso, Marconi, Giovanni, Audisio, Ernesta, Priolo, Giorgio, Papayannidis, Cristina, Martelli, Maurizio, Paoloni, Francesca, Bocchia, Monica, Lanza, Francesco, Lico, Albana, Ciceri, Fabio, Giovanni Della Porta, Matteo, Frigeni, Marco, Giaccone, Luisa, Beltrami, Germana, Borlenghi, Erika, Chiara DI Chio, Maria, Selleri, Carmine, Crea, Enrico, Urbino, Irene, Sartor, Chiara, Minotti, Clara, Arena, Valentina, Nanni, Jacopo, Simonetti, Giorgia, Teresa Bochicchio, Maria, Saglio, Giuseppe, Venditti, Adrianno, Vignetti, Marco, Fazi, Paola, Tedone, Elisabetta, Martinelli, Giovanni, Massimo Lemoli, Roberto

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All Glucose Measurements Are Not Equal by Bilotta, Federico, Caramia, Remo, Paoloni, Francesca P., Delfini, Roberto, Rosa, Giovanni

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The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party by IACOBUCCI, Ilaria, LONETTI, Annalisa, PAOLINI, Stefania, ELIA, Loredana, MESSINA, Monica, VITALE, Antonella, MELONI, Giovanna, SOVERINI, Simona, PANE, Fabrizio, BACCARANI, Michele, FOA, Robin, MARTINELLI, Giovanni, PAOLONI, Francesca, PAPAYANNIDIS, Cristina, FERRARI, Anna, TIZIANA STORLAZZI, Clelia, VIGNETTI, Marco, CILLONI, Daniela, MESSA, Francesca, GUADAGNUOLO, Viviana

“…Recently, in genome-wide analyses of DNA copy number abnormalities using single nucleotide polymorphism microarrays, genetic alterations targeting PAX5 were…”
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White blood cell count at diagnosis and immunoglobulin variable region gene mutations are independent predictors of treatment-free survival in young patients with stage A chronic lymphocytic leukemia by DEL GIUDICE, Ilaria, ROMANA MAURO, Francesca, ARMIENTO, Daniele, PAOLONI, Francesca, GUARINI, Anna, FOA, Robin, STEFANIA DE PROPRIS, Maria, SANTANGELO, Simona, MARINELLI, Marilisa, PERAGINE, Nadia, DI MAIO, Valeria, NANNI, Mauro, BARZOTTI, Rita, MANCINI, Francesca

“…A comprehensive panel of clinical-biological parameters was prospectively evaluated at presentation in 112 patients with chronic lymphocytic leukemia (<65…”
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The therapeutic response and clinical outcome of adults with ALL1(MLL)/AF4 fusion positive acute lymphoblastic leukemia according to the GIMEMA experience by CIMINO, Giuseppe, CENFRA, Natalia, ELIA, Loredana, SICA, Simona, LUPPI, Mario, MELONI, Giovanna, VIGNETTI, Marco, PAOLONI, Francesca, FOA, Robin, MANDELLI, Franco

“…The clinical outcome of 21 adults with ALL1(MLL)/AF4 positive acute lymphoblastic leukemia enrolled in the GIMEMA LAL 2000 trial and of 25 patients entered…”
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Gemtuzumab Ozogamicin Versus Best Supportive Care in Older Patients With Newly Diagnosed Acute Myeloid Leukemia Unsuitable for Intensive Chemotherapy: Results of the Randomized Phase III EORTC-GIMEMA AML-19 Trial by Amadori, Sergio, Suciu, Stefan, Selleslag, Dominik, Aversa, Franco, Gaidano, Gianluca, Musso, Maurizio, Annino, Luciana, Venditti, Adriano, Voso, Maria Teresa, Mazzone, Carla, Magro, Domenico, De Fabritiis, Paolo, Muus, Petra, Alimena, Giuliana, Mancini, Marco, Hagemeijer, Anne, Paoloni, Francesca, Vignetti, Marco, Fazi, Paola, Meert, Liv, Ramadan, Safaa Mahmoud, Willemze, Roel, de Witte, Theo, Baron, Frédéric

“…To compare single-agent gemtuzumab ozogamicin (GO) with best supportive care (BSC) including hydroxyurea as first-line therapy in older patients with acute…”
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Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial by Platzbecker, Uwe, Avvisati, Giuseppe, Cicconi, Laura, Thiede, Christian, Paoloni, Francesca, Vignetti, Marco, Ferrara, Felicetto, Divona, Mariadomenica, Albano, Francesco, Efficace, Fabio, Fazi, Paola, Sborgia, Marco, Di Bona, Eros, Breccia, Massimo, Borlenghi, Erika, Cairoli, Roberto, Rambaldi, Alessandro, Melillo, Lorella, La Nasa, Giorgio, Fiedler, Walter, Brossart, Peter, Hertenstein, Bernd, Salih, Helmut R, Wattad, Mohammed, Lübbert, Michael, Brandts, Christian H, Hänel, Mathias, Röllig, Christoph, Schmitz, Norbert, Link, Hartmut, Frairia, Chiara, Pogliani, Enrico Maria, Fozza, Claudio, D'Arco, Alfonso Maria, Di Renzo, Nicola, Cortelezzi, Agostino, Fabbiano, Francesco, Döhner, Konstanze, Ganser, Arnold, Döhner, Hartmut, Amadori, Sergio, Mandelli, Franco, Ehninger, Gerhard, Schlenk, Richard F, Lo-Coco, Francesco

“…Purpose The initial results of the APL0406 trial showed that the combination of all- trans-retinoic acid (ATRA) and arsenic trioxide (ATO) is at least not…”
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Short course of bortezomib in anemic patients with relapsed cold agglutinin disease: a phase 2 prospective GIMEMA study by Rossi, Giuseppe, Gramegna, Doriana, Paoloni, Francesca, Fattizzo, Bruno, Binda, Francesca, D'Adda, Mariella, Farina, Mirko, Lucchini, Elisa, Mauro, Francesca Romana, Salvi, Flavia, Marchetti, Monia, Fazi, Paola, Zaja, Francesco, Barcellini, Wilma

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Dasatinib as first-line treatment for adult patients with Philadelphia chromosome–positive acute lymphoblastic leukemia by Foà, Robin, Vitale, Antonella, Vignetti, Marco, Meloni, Giovanna, Guarini, Anna, De Propris, Maria Stefania, Elia, Loredana, Paoloni, Francesca, Fazi, Paola, Cimino, Giuseppe, Nobile, Francesco, Ferrara, Felicetto, Castagnola, Carlo, Sica, Simona, Leoni, Pietro, Zuffa, Eliana, Fozza, Claudio, Luppi, Mario, Candoni, Anna, Iacobucci, Ilaria, Soverini, Simona, Mandelli, Franco, Martinelli, Giovanni, Baccarani, Michele

“…Dasatinib is a potent BCR-ABL inhibitor effective in chronic myeloid leukemia and Ph+ acute lymphoblastic leukemia (ALL) resistant/intolerant to imatinib. In…”
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The Addition of Venetoclax to Induction Chemotherapy in No Low-Risk AML Patients: A Propensity Score-Matched Analysis of the Gimema AML1718 and AML1310 Trials by Piciocchi, Alfonso, Messina, Monica, Cipriani, Marta, Paoloni, Francesca, Simonetti, Giorgia, Palmieri, Raffaele, Marconi, Giovanni, Buccisano, Francesco, Fazi, Paola, Vignetti, Marco, Martinelli, Giovanni, Venditti, Adriano

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