Search Results - "Paolo, Maria Luisa Di"
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Fyn specifically Regulates the activity of red cell glucose-6-phosphate-dehydrogenase
Published in Redox biology (01-09-2020)“…Fyn is a tyrosine kinase belonging to the Src family (Src-Family-Kinase, SFK), ubiquitously expressed. Previously, we report that Fyn is important in stress…”
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2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles
Published in Pharmaceuticals (Basel, Switzerland) (09-05-2023)“…A potent nontoxic antitumor drug, 2-hydroxyoleic acid ( , 2OHOA) used for membrane lipid therapy, was selected as a self-assembly inducer due to its ability to…”
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3
Cardiolipin drives the catalytic activity of GPX4 on membranes: Insights from the R152H mutant
Published in Redox biology (01-08-2023)“…The aim of this study was to examine, in biochemical detail, the functional role of the Arg152 residue in the selenoprotein Glutathione Peroxidase 4 (GPX4),…”
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Insight into the mechanism of ferroptosis inhibition by ferrostatin-1
Published in Redox biology (01-01-2020)“…Ferroptosis is a form of cell death primed by iron and lipid hydroperoxides and prevented by GPx4. Ferrostatin-1 (fer-1) inhibits ferroptosis much more…”
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5
Preliminary studies of the effects of vascular adhesion protein-1 inhibitors on experimental corneal neovascularization
Published in Journal of Neural Transmission (01-07-2011)“…Vascular adhesion protein-1 (VAP-1) controls the adhesion of lymphocytes to endothelial cells and is upregulated at sites of inflammation. Moreover, it…”
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6
Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets
Published in Molecules (Basel, Switzerland) (01-11-2023)“…Oxidative stress and neuroinflammation play a pivotal role in triggering the neurodegenerative pathological cascades which characterize neurodegenerative…”
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trans -Dichloro(triphenylarsino)( N , N -dialkylamino)platinum(II) Complexes: In Search of New Scaffolds to Circumvent Cisplatin Resistance
Published in Molecules (Basel, Switzerland) (19-01-2022)“…The high incidence of the resistance phenomenon represents one of the most important limitations to the clinical usefulness of cisplatin as an anticancer drug…”
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Serum Vascular Adhesion Protein-1 and Endothelial Dysfunction in Hepatic Cirrhosis: Searching for New Prognostic Markers
Published in International journal of molecular sciences (03-07-2024)“…Endothelial dysfunction plays a key role in the development of liver cirrhosis. Among the biomarkers of endothelial dysfunction, the soluble form of Vascular…”
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Cannabidiol as Self-Assembly Inducer for Anticancer Drug-Based Nanoparticles
Published in Molecules (Basel, Switzerland) (23-12-2022)“…Cannabidiol (CBD) is a biologically active compound present in the plants of the family, used as anticonvulsant, anti-inflammatory, anti-anxiety, and more…”
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10
From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs
Published in Molecules (Basel, Switzerland) (29-08-2023)“…Monoamine oxidases (MAOs) are well-known pharmacological targets in neurological and neurodegenerative diseases. However, recent studies have revealed a new…”
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11
Dibromo- and Dichlorotriphenylphosphino N-Acyclic Carbene Complexes of Platinum(II)—Synthesis and Cytotoxicity
Published in Inorganics (01-09-2023)“…Some new dichloro- and dibromotriphenylphosphino isonitrile and N-acyclic (NAC) carbene complexes of platinum(II) were synthesized, starting from suitable…”
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12
Spermine Oxidase–Substrate Electrostatic Interactions: The Modulation of Enzyme Function by Neighboring Colloidal ɣ-Fe2O3
Published in Biomolecules (Basel, Switzerland) (15-12-2023)“…Protein–nanoparticle hybridization can ideally lead to novel biological entities characterized by emerging properties that can sensibly differ from those of…”
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13
Coinage Metal Compounds With 4-Methoxy-Diphenylphosphane Benzoate Ligand Inhibit Female Cancer Cell Growth
Published in Frontiers in chemistry (13-07-2022)“…In the continuous effort to find new metal-based compounds as alternatives to platinum-related anticancer drugs, 11 th group metal phosphane compounds have…”
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14
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2019)“…Fourteen polyamine analogues, asymmetric or symmetric substituted spermine (1-9) or methoctramine (10-14) analogues, were evaluated as potential inhibitors or…”
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15
Interaction of copper with cysteine: stability of cuprous complexes and catalytic role of cupric ions in anaerobic thiol oxidation
Published in Journal of inorganic biochemistry (01-09-2004)“…Copper complexes with cysteine have been investigated by optical spectroscopy, NMR and ESR. Cuprous ions strongly bind to the thiol group of Cys forming…”
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Preparation, morphological characterization, and activity of thin films of horseradish peroxidase
Published in Biotechnology and bioengineering (05-06-2000)“…Active uniform films of horseradish peroxidase (HRP) have been prepared by covalent binding on Si/SiO2 or glass supports previously activated by silanization…”
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Dietary ω-3 Fatty Acid Supplementation Improves Murine Sickle Cell Bone Disease and Reprograms Adipogenesis
Published in Antioxidants (18-05-2021)“…Sickle cell disease (SCD) is a genetic disorder of hemoglobin, leading to chronic hemolytic anemia and multiple organ damage. Among chronic organ…”
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Phosphonium compounds as new and specific inhibitors of bovine serum amine oxidase
Published in Biochemical journal (15-12-2004)“…TPP+ (tetraphenylphosphonium ion) and its analogues were found to act as powerful competitive inhibitors of BSAO (bovine serum amine oxidase). The binding of…”
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Tyrosine Phosphorylation Modulates Peroxiredoxin-2 Activity in Normal and Diseased Red Cells
Published in Antioxidants (01-02-2021)“…Peroxiredoxin-2 (Prx2) is the third most abundant cytoplasmic protein in red blood cells. Prx2 belongs to a well-known family of antioxidants, the…”
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Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study
Published in Amino acids (01-02-2012)“…In the last few decades, medicinal chemists have carried out extensive research on synthetic polyamines for use as anticancer drugs and multitarget-directed…”
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