Search Results - "Paolo, Emmanuel Di"
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Interaction of Pneumococcal Histidine Triad Proteins with Human Complement
Published in Infection and Immunity (01-05-2010)“…The pneumococcal histidine triad (Pht) proteins PhtA, PhtB, PhtD, and PhtE form a group of conserved pneumococcal surface proteins. Humans produce antibodies…”
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Long-term immunogenicity of measles, mumps and rubella-containing vaccines in healthy young children: A 10-year follow-up
Published in Vaccine (23-08-2019)“…•Measles-mumps-rubella (MMR)-containing vaccines provide robust immune responses up to 10 years.•Antibody levels persisted above seropositivity threshold for…”
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Assessment of Mumps Virus-Specific Antibodies: Comparison of Plaque Reduction Neutralization Test and Enzyme-Linked Immunosorbent Assay Estimates
Published in The Journal of infectious diseases (01-11-2019)“…The plaque reduction neutralization test (PRNT), which measures a subset of immunoglobulin antibodies (functional neutralizing antibodies), and the…”
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Immunogenicity and safety of the adjuvanted recombinant zoster vaccine in patients with solid tumors, vaccinated before or during chemotherapy: A randomized trial
Published in Cancer (15-04-2019)“…Background The adjuvanted recombinant zoster vaccine (RZV) has demonstrated >90% efficacy against herpes zoster in adults ≥50 years of age and 68% efficacy in…”
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The Adjuvanted Recombinant Zoster Vaccine in Adults Aged ≥65 Years Previously Vaccinated With a Live-Attenuated Herpes Zoster Vaccine
Published in The Journal of infectious diseases (13-10-2021)“…Abstract Background Efficacy of the live-attenuated herpes zoster (HZ) vaccine (ZVL) wanes substantially over time. We evaluated immunogenicity and safety of…”
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Persistence of HBsAg‐specific antibodies and immune memory two to three decades after hepatitis B vaccination in adults
Published in Journal of viral hepatitis (01-09-2019)“…The duration of protection after hepatitis B vaccination is not exactly known. This phase IV study evaluated antibody persistence and immune memory 20‐30 years…”
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UspA2 is a cross-protective Moraxella catarrhalis vaccine antigen
Published in Vaccine (15-09-2021)“…•UspA2 is a potential Moraxella catarrhalis (Mcat) vaccine antigen.•UspA2 was shown to be immunogenic and to protect against lung colonization in mice.•UspA2…”
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Comparison of a glycoprotein E-based ELISA with a varicella-zoster whole-virus ELISA for the quantification of varicella vaccine immune responses in young children
Published in Vaccine (09-04-2020)“…Antibody response against varicella-zoster virus (VZV) is frequently assessed by whole-virus- (anti-VZV) or glycoprotein-based ELISAs. This study compared…”
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Adjuvanted recombinant zoster vaccine in adult autologous stem cell transplant recipients: polyfunctional immune responses and lessons for clinical practice
Published in Human vaccines & immunotherapeutics (02-11-2021)“…Immunocompromised individuals, particularly autologous hematopoietic stem cell transplant (auHSCT) recipients, are at high risk for herpes zoster (HZ). We…”
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Transcriptional regulation, occurrence and putative role of the Pht family of Streptococcus pneumoniae
Published in Microbiology (Society for General Microbiology) (01-02-2011)“…Restricted to the genus Streptococcus, the Pht protein family comprises four members: PhtA, PhtB, PhtD and PhtE. This family has the potential to provide a…”
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Preclinical evaluation of a chemically detoxified pneumolysin as pneumococcal vaccine antigen
Published in Human vaccines & immunotherapeutics (02-01-2017)“…The use of protein antigens able to protect against the majority of Streptococcus pneumoniae serotypes is envisaged as stand-alone and/or complement to the…”
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Immunogenicity and Safety of the Adjuvanted Recombinant Zoster Vaccine in Chronically Immunosuppressed Adults Following Renal Transplant: A Phase 3, Randomized Clinical Trial
Published in Clinical infectious diseases (02-01-2020)“…Abstract Background The incidence of herpes zoster is up to 9 times higher in immunosuppressed solid organ transplant recipients than in the general…”
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Persistence of HB sAg‐specific antibodies and immune memory two to three decades after hepatitis B vaccination in adults
Published in Journal of viral hepatitis (01-09-2019)“…Abstract The duration of protection after hepatitis B vaccination is not exactly known. This phase IV study evaluated antibody persistence and immune memory…”
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Pneumococcal serotype 3 otitis media, limited effect of polysaccharide conjugate immunisation and strain characteristics
Published in Vaccine (21-05-2009)“…Abstract Background In contrast to the other vaccine serotypes, no protection could be demonstrated in the POET study against serotype 3 acute otitis media…”
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Properties of the VIP-PACAP type II receptor stably expressed in CHO cells
Published in Regulatory peptides (15-12-1994)“…The VIP receptor cloned from rat lung (VIP1 receptor from the group of the PACAP-VIP type II receptors) was inserted into a mammalian expression vector and…”
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149. Immunogenicity, Safety, and Post-hoc Efficacy Assessment of the Adjuvanted Recombinant Zoster Vaccine in Adults with Hematologic Malignancies: A Phase 3, Randomized Clinical Trial
Published in Open forum infectious diseases (26-11-2018)“…Abstract Background Patients with hematologic malignancies treated with anticancer immunosuppressive therapies (ITs) are at increased risk of herpes zoster…”
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Properties of a recombinant human secretin receptor : A comparison with the rat and rabbit receptors
Published in Pancreas (01-07-1999)“…A secretin receptor was cloned from a commercial human pancreatic complementary DNA (cDNA) bank. The amino acid sequence deduced from the nucleotide sequence…”
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Contribution of the second transmembrane helix of the secretin receptor to the positioning of secretin
Published in FEBS letters (13-03-1998)“…The secretin amino-terminal residues are essential for high affinity binding to its cognate receptor and for its biological activity. Mutation of the [Asp 3]…”
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Properties of Chimeric Secretin and VIP Receptor Proteins Indicate the Importance of the N-Terminal Domain for Ligand Discrimination
Published in Biochemical and biophysical research communications (26-06-1995)“…Two chimeras were obtained by substituting the DNA sequence encoding the N-terminal extracellular domain of the VIP and secretin receptors by the homologous…”
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